A shaft of warm light across a deep amber-gold wall
The Longevity Code · Healthy Aging

A Molecule Named for Its Rings

Pyrroloquinoline quinone takes its name from its structure: a stack of three ring systems, one after another. A look at what pyrroloquinoline quinone is, how it was named, where it was first found, and the forms it takes.

Its name reads like a set of directions through its own structure: pyrrole, quinoline, quinone, three rings in sequence.

Pyrroloquinoline quinone, usually shortened to PQQ, is a small quinone compound first identified in bacteria. What follows is the story of the molecule and its name: what it is, where it was found, and the forms it takes.

I The name

A molecule, named for its rings

Pyrroloquinoline quinone is a small organic compound, and its name is really a description of its shape. The name stacks three pieces of chemistry in a row: pyrrole, a small ring; quinoline, a fused ring system; and quinone, a ring that carries a pair of carbonyl groups.

Read that way, the name is a map of the molecule. It is usually shortened, mercifully, to PQQ. As a pure compound it is a deep reddish-amber solid, and it was first identified in certain bacteria several decades ago.

This piece follows the molecule and its name: what pyrroloquinoline quinone is, where it was first found, and the forms it takes, set within the wider study of how the body sustains itself across time.

Pyrrole, quinoline, quinone: three rings in sequence
A rough reddish-amber crystalline mineral mass in raking light

The name

Three rings, in sequence

Pyrrole, quinoline, quinone: the name sets down the three ring systems of the molecule, one after another.

II

The molecule

Pyrroloquinoline quinone, in brief

A few of the plain facts about the molecule and its name.

The Name

The name stacks three ring systems: pyrrole, quinoline, and quinone.

A Quinone

It belongs to the quinones, a class of colored organic compounds.

First Found in Bacteria

It was first identified in certain bacteria several decades ago.

Its Forms

It appears as the free acid and as a disodium salt, usually shortened to PQQ.

Warm light refracting through a deep amber translucent form

The rings

Named, ring by ring

Each part of the name marks a ring: the pyrrole, the quinoline, and the quinone that give the molecule its shape.

III

Ring by ring

The name, ring by ring

The parts the name is built from, described by their chemistry, not their use.

The first ring

Pyrrole

Chemistry
A five-membered ring holding one nitrogen
In the name
The "pyrrolo" at the front
Noted for
The smallest of the three rings.
The fused rings

Quinoline

Chemistry
A fused, double-ring system
In the name
The "quinoline" in the middle
Noted for
The core the others attach to.
The last ring

Quinone

Chemistry
A ring carrying two carbonyl groups
In the name
The "quinone" at the end
Noted for
The part that lends the color.
The molecule

The Whole

Chemistry
The three fused into one small compound
In the name
Pyrroloquinoline quinone, or PQQ
Noted for
The complete molecule the name describes.

The molecule

A single molecule

A single translucent faceted crystalline solid, warm amber cast

Beneath the long name and its three rings sits one small compound, a deep reddish-amber solid named for its own shape.

Up close

The molecule, in detail

Extreme macro of a translucent faceted reddish-amber crystalline solid
The compound

Pyrroloquinoline quinone as a pure crystalline solid.

A smooth dark stone under a shaft of warm light
The name

Three rings, set down one after another.

A small cluster of reddish-amber crystals in a shallow dish
The forms

The free acid and the disodium salt.

The molecule, one by one

Pyrroloquinoline quinone, one by one

The plain facts about the molecule and its name, ring by ring:

01
Named for Its Rings
The name stacks three ring systems: pyrrole, quinoline, quinone.
02
A Small Quinone
It belongs to the quinones, a class of colored organic compounds.
03
First Found in Bacteria
It was first identified in certain bacteria several decades ago.
04
A Reddish-Amber Solid
As a pure compound it is a deep reddish-amber crystalline solid.
05
The Free Acid and a Salt
It appears as the free acid and as a disodium salt.
06
Shortened to PQQ
Its long name is usually shortened simply to PQQ.

In the literature

A much-studied molecule

Pyrroloquinoline quinone, the quinone named for its three rings and first found in bacteria, has been examined widely across the scientific literature. The discussion is broad and ongoing, and much of it remains open rather than settled.

On pyrroloquinoline quinone in the research literature

This article is provided for educational and informational purposes only and has been reviewed against FDA and FTC guidelines to ensure it does not make any health, disease, or treatment claim. Any research or studies referenced were conducted independently and did not involve Codeage products; no Codeage product has been used in any study or to establish, prove, or imply any benefit. These statements have not been evaluated by the Food and Drug Administration. Codeage products are not intended to diagnose, treat, cure, or prevent any disease.

The name

A molecule, and its name

Pyrroloquinoline quinone is, in the end, a small compound with a long and literal name: three rings, set down in the order they appear. It is one molecule among many found in the living world, described here by its chemistry and its history alone.

A small quinone named for its own shape: pyrrole, quinoline, quinone.

In closing

Named for its rings

Read from front to back, pyrroloquinoline quinone is a molecule that spells out its own structure: pyrrole, quinoline, and quinone, three rings fused into one small reddish-amber compound, first found in bacteria and usually shortened to PQQ.

None of it is a secret, and none of it is a promise. It is simply what the molecule is, and where its name comes from, one small compound set within the wider story of how the body sustains itself across time.

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