Methylation
Methylfolate B Complex+
For the pathways within. Codeage Methylfolate B Complex+ brings together folate as Quatrefolic® 5-MTHF, vitamin B12 as methylcobalamin, riboflavin and vitamin B6 in their phosphorylated forms, and betaine as trimethylglycine. 2-month supply.
- Folate as Quatrefolic® [6S]-5-methyltetrahydrofolate
- Methylcobalamin B12 with phosphorylated B2 and B6
- Betaine as trimethylglycine, with a 2-month supply
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- Third-party tested
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Manufactured in the USA
Produced with global ingredients in a cGMP-certified facility.
NSF Certified
Independently tested by a trusted third party for purity, potency, and label accuracy.
Non-GMO, Vegan & Clean
Non-GMO, vegan, dairy-, soy-, and gluten-free.
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The Formula
The Methylated Forms
Four B vitamins in their methylated and phosphorylated forms, with betaine beside them.
Folate
1,360mcg DFE
As Quatrefolic® [6S]-5-methyltetrahydrofolate.
Vitamin B12
1,000mcg
As methylcobalamin.
Betaine
600mg
As trimethylglycine, TMG.
Phosphorylated B
+2
Riboflavin-5'-phosphate and pyridoxal-5'-phosphate.
Everything else
The details, when you want them.
Supplement Facts

Product Details
- Folate as Quatrefolic® 5-MTHF: Codeage Methylfolate B Complex+ is built on folate as Quatrefolic® [6S]-5-methyltetrahydrofolate with glucosamine salt.
- Vitamin B12 as Methylcobalamin: Vitamin B12 appears here as methylcobalamin rather than as cyanocobalamin, alongside the folate.
- Phosphorylated B2 and B6: Riboflavin as riboflavin-5’-phosphate and vitamin B6 as pyridoxal-5’-phosphate complete the four B vitamins on the panel.
- Betaine as Trimethylglycine: Betaine sits beside the B vitamins as trimethylglycine, in a formula designed for adults building a daily B-vitamin routine.
- NSF Certified & Manufactured in the USA: Produced in a cGMP-certified facility in the USA with global ingredients, non-GMO, and formulated without dairy, soy, or gluten, in vegetable capsules.
How to Use
Adults take 2 capsules daily, or as recommended by your healthcare practitioner, with 8 ounces of water or your favorite beverage. May be taken with or without food.
CAUTION: Do not exceed recommended dose. Pregnant or nursing mothers, children under 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Discontinue use two weeks prior to surgery. Please use caution if you have allergies or sensitivities to any of the listed ingredients. Keep out of reach of children and pets. Store in a cool, dry place.
Ingredients
Riboflavin (as Riboflavin-5'-Phosphate), Vitamin B6 (as Pyridoxal-5'-Phosphate), Folate (as Quatrefolic® [6S]-5-Methyltetrahydrofolate, Glucosamine Salt), Vitamin B12 (as Methylcobalamin), Betaine (as Trimethylglycine). Other Ingredients: Methylcellulose Capsule, Microcrystalline Cellulose, L-Leucine.
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Questions
Asked and answered.
What is Methylfolate B Complex+?
Methylfolate B Complex+ is a B vitamin formulation built around methylated and phosphorylated forms of key B vitamins, including folate as Quatrefolic 5-MTHF, vitamin B12 as methylcobalamin, riboflavin as riboflavin-5'-phosphate, vitamin B6 as pyridoxal-5'-phosphate, and betaine as trimethylglycine. It comes in vegetable capsules and is formulated for adults building a daily B vitamin routine.
What ingredients are in this formula and in what forms?
Each serving provides riboflavin as riboflavin-5'-phosphate, vitamin B6 as pyridoxal-5'-phosphate, folate as Quatrefolic [6S]-5-methyltetrahydrofolate with glucosamine salt, vitamin B12 as methylcobalamin, and betaine as trimethylglycine. The capsule itself is made of methylcellulose, with microcrystalline cellulose and L-leucine as other ingredients.
Who is this supplement formulated for?
This formula is formulated for adults who want a daily B vitamin routine built on methylated and phosphorylated forms. Read the label for indications and warnings.
How is this product manufactured and verified?
Methylfolate B Complex+ is produced in a cGMP-certified facility in the United States using globally sourced ingredients, and it carries NSF certification. Manufactured in the USA.
Is this formula free from common allergens?
Yes. Methylfolate B Complex+ is formulated without dairy, soy, or gluten, is non-GMO, and is made in vegetable capsules. Formulated without dairy, soy, or gluten. Non-GMO. Manufactured in the USA in a cGMP-certified facility with global ingredients.
What makes the composition of this B complex distinct?
This formula pairs folate as Quatrefolic 5-MTHF with vitamin B12 as methylcobalamin rather than cyanocobalamin, and includes riboflavin and vitamin B6 in their phosphorylated forms, riboflavin-5'-phosphate and pyridoxal-5'-phosphate. Betaine as trimethylglycine is also included alongside these four B vitamins, giving the formula a methylation-focused ingredient profile.
Can this be taken alongside prescription medications or other supplements?
Yes, consulting a healthcare professional before starting any dietary supplement is a sound practice for everyone. This is especially important if you are taking prescription medications or other supplements, have a known medical condition, are pregnant or nursing, or are under eighteen.
Can this be taken with or without food?
Yes. Methylfolate B Complex+ can be taken with or without food, mixed with about eight ounces of water or another beverage of your choice.
How many capsules are in a supply, and how often would I take them?
This product is designed as a two-month supply based on the suggested use of two capsules per day. It is intended to be taken once daily as part of a regular routine.
Does this product disclose the specific chemical form of each ingredient?
Yes. Methylfolate B Complex+ names the specific form of each B vitamin: riboflavin as riboflavin-5'-phosphate, vitamin B6 as pyridoxal-5'-phosphate, folate as Quatrefolic [6S]-5-methyltetrahydrofolate with glucosamine salt, vitamin B12 as methylcobalamin, and betaine as trimethylglycine.
What form does this supplement come in?
Methylfolate B Complex+ is delivered in vegetable capsules, taken two per day with water or another beverage, rather than as a powder or liquid.
Still deciding? Our team answers by chat, phone, or email. AI-generated beta content may contain errors and may not have been reviewed by our team. This is not medical advice; always consult a qualified healthcare professional before using any supplement.
The Longevity Code
Build your longevity routine.
| Where it sits | The daily base | The body's scaffolding | The molecular layer | The systemic layer |
|---|---|---|---|---|
| Key nutrients | Riboflavin, B6, methylfolate, B12, betaine | Marine collagen peptides, biotin, vitamin C, vitamin E, hyaluronic acid | NAD+, betaine anhydrous | CognatiQ, DHH-B, GABA, ashwagandha, organic mushroom blend, blueberry blend |
| Serving | 2 capsules daily | 2 capsules daily | 2 capsules daily | 2 capsules daily |
| Supply | 60 days | — Not listed | 30 days | 30 days |
| Delivery | Capsule | Capsule | Helix liposomal | Capsule |
| Who is it for | For adults building a daily B-vitamin routine | For those adding collagen to their day | For anyone building a daily cellular longevity routine | For anyone building a daily mind-focused routine |
| Regular price $36.99 |
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AI-generated beta content may contain errors and may not have been reviewed by our team. This is not medical advice; always consult a qualified healthcare professional before using any supplement.