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The Botanical
Architecture of
Circulatory Wellness
A modern case study in considered botanical formulation — where seven plant-derived ingredients and vitamin C converge in a single daily composition.
Codeage Veins Vitamins+ brings together a 1,000 mg proprietary blend of diosmin and hesperidin from immature Citrus sinensis, 300 mg of horse chestnut seed extract standardized to 20% aescin, 150 mg of butcher's broom root extract standardized to 20% ruscogenins, 150 mg of gotu kola 4:1 extract, 150 mg of pine bark extract standardized to 95% proanthocyanidins, 100 mg of dandelion 10:1 leaf extract, and 100 mg of vitamin C — in vegetable capsules featuring Codeage Helix Liposomal Delivery. 30 servings. One month of daily use.
This is a formula in which every botanical carries a lineage—centuries of traditional use, modern scientific inquiry, and precise standardization. Eight ingredients. No ornament. Pure compositional intent.
The Logic of Botanical Composition
A single botanical ingredient has its own merit — a focused compound with a singular identity. But the human circulatory system is not singular. It is an intricate network — arteries, veins, capillaries, and the tissues that surround them — a living architecture that extends throughout the body.
A formula designed with circulatory wellness in mind might consider this complexity. Not by adding botanicals for the sake of a longer label, but by selecting each one for a specific compositional reason — the way a master watchmaker selects each complication not for decoration, but for function.
Codeage Veins Vitamins+ is that kind of composition. Seven botanical inputs and one essential vitamin, each precisely standardized, unified by a liposomal delivery system. A formula where nothing is decorative and nothing is accidental.
The Composition — Eight Ingredients, One Thesis
Every ingredient in this formula was selected with specificity. Not a generic extract, but a named plant species — often a specific plant part — standardized to a defined concentration of active compounds. This level of botanical precision is itself a formulation philosophy.
Diosmin & Hesperidin
Diosmin and hesperidin are citrus bioflavonoids — polyphenolic compounds found naturally in citrus fruits, particularly in the peel and pulp of immature oranges. Diosmin is a flavone glycoside, while hesperidin is a flavanone glycoside. Together, they form the compositional foundation of this formula at 1,000 mg — the largest single dose in the blend.
The sourcing from immature Citrus sinensis is a deliberate upstream decision. Immature citrus fruits contain higher concentrations of these bioflavonoids than their ripe counterparts — a botanical distinction that begins in the orchard, not the laboratory.
Diosmin has been the subject of considerable scientific inquiry. A 2016 review published in Nutrients examined the existing body of research on diosmin and its pharmacological properties, noting that it has been studied across multiple dimensions related to vascular biology and circulatory function support.*
Zheng et al. — "Diosmin: A Review of Pharmacological Activity" · Nutrients, 2016Horse Chestnut Seed Extract
Horse chestnut (Aesculus hippocastanum) is a tree native to the Balkans whose seeds have been used in European botanical traditions for centuries. The active compound of interest is aescin (also written escin) — a mixture of triterpene saponins. This extract is standardized to 20% aescin, ensuring a consistent and defined concentration in every serving.
Standardization to a specific percentage of an active compound is a formulation commitment to consistency. It means the amount of aescin is not left to the natural variability of the plant — it is verified and controlled.
A Cochrane systematic review — one of the most rigorous review formats in evidence-based research — examined multiple randomized controlled trials investigating horse chestnut seed extract in the context of chronic venous insufficiency support.*
Pittler & Ernst — "Horse chestnut seed extract for chronic venous insufficiency" · Cochrane Database of Systematic Reviews, 2012Butcher's Broom Root Extract
Butcher's broom (Ruscus aculeatus) is an evergreen shrub native to the Mediterranean region, with a long history of use in traditional European herbalism. The root and rhizome contain ruscogenins — steroidal saponins that are the primary compounds of interest. This extract is standardized to 20% ruscogenins, a precise concentration that reflects thoughtful raw material selection.
The combination of butcher's broom alongside horse chestnut and citrus bioflavonoids creates a triad of European botanical tradition — three plant families, each with centuries of documented historical use, now unified in a single modern composition.
Gotu Kola 4:1 Extract
Gotu kola (Centella asiatica) is a perennial herb found across tropical and subtropical Asia, with deep roots in Ayurvedic and traditional Chinese botanical practices. Its principal active compounds include triterpenoids — asiaticoside, madecassoside, asiatic acid, and madecassic acid. The 4:1 extract ratio means that four parts of raw plant material are concentrated into one part of extract.
Where the European botanicals in this formula draw from Western traditions, gotu kola introduces an Asian botanical lineage. This is not eclecticism. It is the recognition that botanical wisdom is global.
Pine Bark Extract
Pine bark extract from Pinus pinaster — the maritime pine native to the Mediterranean — is among the most extensively studied botanical extracts in modern phytochemistry. Its primary active constituents are proanthocyanidins (also known as oligomeric proanthocyanidin complexes, or OPCs). This extract is standardized to 95% proanthocyanidins — one of the highest standardization levels available.
Pine bark extract from Pinus pinaster has been the subject of published research. A 2020 review in Phytotherapy Research surveyed the existing scientific literature on pine bark extract and its studied properties in the context of cardiovascular and vascular biology support.*
Malekahmadi et al. — "Effects of Pycnogenol on Cardiometabolic Parameters" · Phytotherapy Research, 2020Dandelion 10:1 Leaf Extract
Dandelion (Taraxacum officinale) is perhaps the most unassuming botanical in this composition — and yet its presence signals the depth of the formulation thinking. Known to most as a common meadow plant, dandelion has been used in traditional herbal practices across European, Chinese, and Native American traditions for centuries. The 10:1 extract ratio provides a concentrated form — ten parts of raw plant material condensed into one part of extract.
Vitamin C
Vitamin C is the sole non-botanical ingredient in this formula — and its presence is anything but incidental. Vitamin C is an essential nutrient that contributes to normal collagen formation, which supports the normal function of blood vessels. At 100 mg per serving (111% of the Daily Value), it serves as both a standalone essential nutrient and a compositional counterpart to the botanical blend.
Standardization as Craft
Four of the seven botanicals in this formula are standardized to specific concentrations of their principal active compounds. This is a detail worth pausing on.
Standardization means that the concentration of the key compound is verified, consistent, and controlled. It is the difference between a plant that may contain a compound and an extract that can deliver a defined amount of it.
A refined botanical formula is not measured by the number of plants it contains. It is measured by the precision with which each plant is prepared.
This is the invisible craftsmanship of phytochemical formulation — the work that happens between the field and the serving, where raw botanical material is transformed into a defined, reproducible extract.
Liposomal Delivery — The Final Layer
Formulation thinking that ends at ingredient selection is incomplete. The final act of this composition is the delivery system itself.
Phospholipids from Non-GMO
Sunflower Lecithin
A lipid-based encapsulation system featuring phosphatidylcholine — creating a structural phospholipid layer around the botanical composition. The delivery system is the invisible architecture that may help carry every ingredient forward.*
The inclusion of a proprietary liposomal system reflects a belief that formulation thinking should extend beyond ingredient selection. The capsule is not just a container. It is the final layer of the composition — from botanical to encapsulation to ritual.
The Refinement Standard
Maintaining a refined profile across a seven-botanical composition with standardized extracts and a liposomal delivery system is a discipline that compounds at every level of the supply chain.
Manufactured in the USA with global ingredients in a cGMP-certified facility for quality and purity. Methylcellulose vegetable capsules.
30 servings.
The Broader Thesis: Botanical Wisdom Is Compositional
Each botanical in this formula carries its own history — some stretching back centuries in European herbalism, others rooted in Asian traditional practice. But the thesis of this formula is not that any one botanical is sufficient. Botanical intelligence is compositional.
Codeage Veins Vitamins+ is a seven-layer botanical composition — bioflavonoids, saponins, polyphenols, triterpenoids, whole-plant extract, micronutrient, and liposomal delivery — unified in four daily capsules.
Conclusion: Seven Botanicals, One Composition
Codeage Veins Vitamins+ brings together a 1,000 mg proprietary blend of diosmin and hesperidin from immature Citrus sinensis, 300 mg of horse chestnut seed extract (standardized to 20% aescin), 150 mg of butcher's broom root extract (standardized to 20% ruscogenins), 150 mg of gotu kola 4:1 extract, 150 mg of pine bark extract (standardized to 95% proanthocyanidins), 100 mg of dandelion 10:1 leaf extract, and 100 mg of vitamin C — in vegetable capsules featuring Codeage Helix Liposomal Delivery.
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