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Liposomal Vitamin C +

Advanced Vitamin C Capsules. 2 Months Supply.
    $35.99
    160 reviews
    1500mg Vitamin C

    Description

    Product Details

    • 1500 mg of vitamin C per serving
    • Citrus bioflavonoid complex with grapefruit, lemon, and orange powder
    • 15 mg of zinc
    • Quercetin
    • Elderberry
    • Rosehips extract
    • Alpha lipoic acid
    • Features non-GMO sunflower phosphatidylcholine (from lecithin) for liposomal delivery
    • Vegan
    • Non-GMO
    • Soy-free, and plant based
    • Vegan capsules
    • Manufactured in the USA in a cGMP facility
    • Third-party tested
    • 2 months supply
    • Also exists in liquid format

    Featured Ingredients

    Vitamin C

    1,500mg  

    Citrus Bioflavonoid Complex

    Grapefruit, lemon, and orange powder

    Elderberry Powder

    Antioxidant properties*

    Quercetin

    50 mg 

    Zinc 

    15 mg

    The modern vitamin C

    High dose of 1,500mg vitamin C, zinc, citrus bioflavonoids with grapefruit, lemon, and orange powders. Features elderberry powder, quercetin, and rosehips extracts.

    Suggested use

    Take 3 capsules daily with 8 ounces of water or your favorite beverage. May be taken with or without food.

    See caution

    CAUTION: Do not exceed recommended dose. Please use caution if you have allergies or sensitivities to any of the listed ingredients. Pregnant or nursing mothers and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Use only as directed. If gastrointestinal discomfort (including bloating, cramps, diarrhea, or other digestive upset) or other sensitivity is experienced stop taking the product immediately. If you are pregnant, nursing, or have a medical condition, please consult with your physician before use. If you have any questions about consuming this dietary supplement, consult with your health care professional before using. If you use prescription drugs or over-the-counter medications, are unaware of your current medical condition or have a pre-existing medical condition(s), consult with your health care professional before using. Discontinue use immediately if you experience any adverse symptoms or reactions while taking this product. Discontinue use 2 weeks prior to surgery. Do not use if your health status is unknown. Do not use if safety seal is damaged or missing. Keep out of reach of children and pets. Store in a cool, dry place, away from heat moisture. Use this product as a food supplement only. Do not use for weight reduction.

    Additional Details

    The modern vitamin C

    High dose of 1,500mg vitamin C, zinc, citrus bioflavonoids with grapefruit, lemon, and orange powders. Features elderberry powder, quercetin, and rosehips extracts.

    See all ingredients

    Ingredients:

    Vitamin C (as Ascorbic Acid), Zinc (as Amino Acid Chelate), Phosphatidylcholine (from Sunflower Lecithin), Alpha Lipoic Acid, Citrus Bioflavonoid Complex: Grapefruit Powder (Fruit), Lemon Powder (Peel), Orange Powder (Fruit), Quercetin Dihydrate, Rosehips Extract (Fruit), Elderberry Powder (Fruit). Other Ingredients: Methylcellulose Capsule.

    Pairs With

    References

    Vitamin C

    Chambial S, Dwivedi S, Shukla KK, John PJ, Sharma P. Vitamin C in disease prevention and cure: an overview. Indian J Clin Biochem. 2013;28(4):314328.  doi: 10.1007/s12291-013-0375-3

    Traber MG, Stevens JF. Vitamins C and E: beneficial effects from a mechanistic perspective. Free Radic Biol Med. 2011;51(5):10001013. doi: 10.1016/j.freeradbiomed.2011.05.017

    See more

    Padayatty, S. J., Katz, A., Wang, Y., Eck, P., Kwon, O., Lee, J. H., Chen, S., Corpe, C., Dutta, A., Dutta, S. K., & Levine, M. (2003). Vitamin C as an antioxidant: evaluation of its role in disease prevention. Journal of the American College of Nutrition, 22(1), 1835. DOI: 10.1080/07315724.2003.10719272

    Pehlivan, Fadime. (2017). Vitamin C: An Antioxidant Agent. 10.5772/intechopen.69660. DOI: 10.5772/intechopen.69660

    A. Bendich, L.J. Machlin, O. Scandurra, G.W. Burton, D.D.M. Wayner, The antioxidant role of vitamin C, Advances in Free Radical Biology & Medicine, Volume 2, Issue 2, 1986, 419-444, 8755-9668. https://doi.org/10.1016/S8755-9668(86)80021-7

    Marc Bürzle, Matthias A. Hediger. Chapter Eleven: Functional and Physiological Role of Vitamin C Transporters. Mark O. Bevensee. Current Topics in Membranes. Academic Press. 70. 2012. 357-375. 1063-5823. 9780123943163. https://doi.org/10.1016/B978-0-12-394316-3.00011-9

    Akbari, Abolfazl & Jelodar, Gholamali & Nazifi, Saeed & Sajedianfard, Javad. (2016). An Overview of The characteristics and Function of Vitamin C in Various Tissues: Relying on its Antioxidant Function. Zahedan Journal of Research in Medical Sciences. In Press. DOI: 10.17795/zjrms-4037

    Chakraborthy, Aratirika & Ramani, Pratibha & Sherlin, Herald & Premkumar, Priya & Natesan, Anuja. (2014). Antioxidant and pro-oxidant activity of Vitamin C in oral environment. Indian journal of dental research : official publication of Indian Society for Dental Research. 25. 499-504. DOI: 10.4103/0970-9290.142547

    Sirmali, Rana & Giniş, Zeynep & Sirmali, Mehmet & Solak, Okan & Şeliman, Bengü & Ağaçkiran, Yetkin & Delibaş, Namık. (2014). Vitamin C as an antioxidant: evaluation of its role on pulmonary contusion experimental model. Turkish journal of medical sciences. 44. 905-13. DOI: 10.3906/sag-1309-139

    Citrus Bioflavonoid Complex

    Stevens, Y., Rymenant, E. V., Grootaert, C., Camp, J. V., Possemiers, S., Masclee, A., & Jonkers, D. (2019). The Intestinal Fate of Citrus Flavanones and Their Effects on Gastrointestinal Health. Nutrients, 11(7), 1464. DOI: 10.3390/nu11071464

    Testai L, Calderone V. Nutraceutical Value of Citrus Flavanones and Their Implications in Cardiovascular Disease. Nutrients. 2017;9(5):502. Published 2017 May 16. doi: 10.3390/nu9050502

    Barreca, D., Gattuso, G., Bellocco, E., Calderaro, A., Trombetta, D., Smeriglio, A., Laganà, G., Daglia, M., Meneghini, S., & Nabavi, S. M. (2017). Flavanones: Citrus phytochemical with health-promoting properties. BioFactors (Oxford, England), 43(4), 495506. DOI: 10.1002/biof.1363

    Sharma, M., Akhtar, N., Sambhav, K., Shete, G., Bansal, A. K., & Sharma, S. S. (2015). Emerging potential of citrus flavanones as an antioxidant in diabetes and its complications. Current topics in medicinal chemistry, 15(2), 187195. DOI: 10.2174/1568026615666141209163013

    Chanet, A., Milenkovic, D., Manach, C., Mazur, A., & Morand, C. (2012). Citrus flavanones: what is their role in cardiovascular protection?. Journal of agricultural and food chemistry, 60(36), 88098822. DOI: 10.1021/jf300669s

    Zaidun, N. H., Thent, Z. C., & Latiff, A. A. (2018). Combating oxidative stress disorders with citrus flavonoid: Naringenin. Life sciences, 208, 111122. DOI: 10.1016/j.lfs.2018.07.017

    Assini, J. M., Mulvihill, E. E., & Huff, M. W. (2013). Citrus flavonoids and lipid metabolism. Current opinion in lipidology, 24(1), 3440. DOI: 10.1097/MOL.0b013e32835c07fd

    Asgary, S., Naderi, G., & Askari, N. (2005). Protective effect of flavonoids against red blood cell hemolysis by free radicals. Experimental and clinical cardiology, 10(2), 8890. PMCID: PMC2716227

    Elderberry Powder

    Sidor, Andrzej & Gramza Michalowska, Anna. (2014). Advanced research on the antioxidant and health benefit of elderberry (Sambucus nigra) in food a review. Journal of Functional Foods. 18. DOI: 10.1016/j.jff.2014.07.012

    Porter, R. S., & Bode, R. F. (2017). A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products. Phytotherapy research : PTR, 31(4), 533554. DOI: 10.1002/ptr.5782

    Zakay-Rones, Z., Thom, E., Wollan, T., & Wadstein, J. (2004). Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections. The Journal of international medical research, 32(2), 132140. DOI: 10.1177/147323000403200205

    Barak, V., Halperin, T., & Kalickman, I. (2001). The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. European cytokine network, 12(2), 290296. PMID: 11399518

    Hawkins, J., Baker, C., Cherry, L., & Dunne, E. (2019). Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials. Complementary therapies in medicine, 42, 361365. DOI: 10.1016/j.ctim.2018.12.004

    Tiralongo E, Wee SS, Lea RA. Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial. Nutrients. 2016;8(4):182. Published 2016 Mar 24. doi: 10.3390/nu8040182

    Porter, R. S., & Bode, R. F. (2017). A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products. Phytotherapy research : PTR, 31(4), 533554. DOI: 10.1002/ptr.5782

    Quercetin

    Selamoglu, Zeliha. (2016). Antioxidant Activity of Quercetin: A Mechanistic Review. Turkish Journal of Agriculture - Food Science and Technology. 4. 10.24925/turjaf.v4i12.1134-1138.1069. DOI: 10.24925/turjaf.v4i12.1134-1138.1069

    Anand David AV, Arulmoli R, Parasuraman S. Overviews of Biological Importance of Quercetin: A Bioactive Flavonoid. Pharmacogn Rev. 2016;10(20):8489. doi: 10.4103/0973-7847.194044

    Serban, M. C., Sahebkar, A., Zanchetti, A., Mikhailidis, D. P., Howard, G., Antal, D., Andrica, F., Ahmed, A., Aronow, W. S., Muntner, P., Lip, G. Y., Graham, I., Wong, N., Rysz, J., Banach, M., & Lipid and Blood Pressure Metaanalysis Collaboration (LBPMC) Group (2016). Effects of Quercetin on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Journal of the American Heart Association, 5(7), e002713. DOI: 10.1161/JAHA.115.002713

    Xu D, Hu MJ, Wang YQ, Cui YL. Antioxidant Activities of Quercetin and Its Complexes for Medicinal Application. Molecules. 2019;24(6):1123. Published 2019 Mar 21. doi: 10.3390/molecules24061123

    Alía, M., Mateos, R., Ramos, S., Lecumberri, E., Bravo, L., & Goya, L. (2006). Influence of quercetin and rutin on growth and antioxidant defense system of a human hepatoma cell line (HepG2). European journal of nutrition, 45(1), 1928. DOI: 10.1007/s00394-005-0558-7

    Robaszkiewicz, A., Balcerczyk, A., & Bartosz, G. (2007). Antioxidative and prooxidative effects of quercetin on A549 cells. Cell biology international, 31(10), 12451250. DOI: 10.1016/j.cellbi.2007.04.009

    Kim, G. N., & Jang, H. D. (2009). Protective mechanism of quercetin and rutin using glutathione metabolism on HO-induced oxidative stress in HepG2 cells. Annals of the New York Academy of Sciences, 1171, 530537. DOI: 10.1111/j.1749-6632.2009.04690.x

    Baghel, Satyendra & Shrivastava, Nikhil & Baghel, PA & Rajput, Sarlesh. (2012). A review of quercetin: Antioxidant and anticancer properties. World J Pharm Pharmaceutical Sci. 1. 146 - 160.

    Zinc 

    Kaltenberg, J., Plum, L. M., Ober-Blöbaum, J. L., Hönscheid, A., Rink, L., & Haase, H. (2010). Zinc signals promote IL-2-dependent proliferation of T cells. European journal of immunology, 40(5), 14961503. DOI: 10.1002/eji.200939574

    Shankar, A. H., & Prasad, A. S. (1998). Zinc and immune function: the biological basis of altered resistance to infection. The American journal of clinical nutrition, 68(2 Suppl), 447S463S. DOI: 10.1093/ajcn/68.2.447S

    Barnett, J. B., Dao, M. C., Hamer, D. H., Kandel, R., Brandeis, G., Wu, D., Dallal, G. E., Jacques, P. F., Schreiber, R., Kong, E., & Meydani, S. N. (2016). Effect of zinc supplementation on serum zinc concentration and T cell proliferation in nursing home elderly: a randomized, double-blind, placebo-controlled trial. The American journal of clinical nutrition, 103(3), 942951. DOI: 10.3945/ajcn.115.115188

    Barnett JB, Hamer DH, Meydani SN. Low zinc status: a new risk factor for pneumonia in the elderly? Nutrition Reviews. 2010 Jan;68(1):30-37. DOI: 10.1111/j.1753-4887.2009.00253.x 

    Yasuda, Hiroshi. (2017). The Situation of Zinc Deficiency: Early Assessment and Intervention Are Essential. Biomedical Research on Trace Elements. 125-140. DOI: 10.11299/brte.27.125

    Hemilä H. Zinc lozenges may shorten the duration of colds: a systematic review. Open Respir Med J. 2011;5:5158. doi: 10.2174/1874306401105010051

    Rerksuppaphol, S., & Rerksuppaphol, L. (2013). A randomized controlled trial of chelated zinc for prevention of the common cold in Thai school children. Paediatrics and international child health, 33(3), 145150. DOI: 10.1179/2046905513Y.0000000064

    [more] Shade CW. Liposomes as Advanced Delivery Systems for Nutraceuticals. Integr Med (Encinitas). 2016;15(1):3336. PMID: 27053934

    Supplement Facts

    Ingredients

    Suggested Use

    References

    Product Details

    • 1500 mg of vitamin C per serving
    • Citrus bioflavonoid complex with grapefruit, lemon, and orange powder
    • 15 mg of zinc
    • Quercetin
    • Elderberry
    • Rosehips extract
    • Alpha lipoic acid
    • Features non-GMO sunflower phosphatidylcholine (from lecithin) for liposomal delivery
    • Vegan
    • Non-GMO
    • Soy-free, and plant based
    • Vegan capsules
    • Manufactured in the USA in a cGMP facility
    • Third-party tested
    • 2 months supply
    • Also exists in liquid format

    Featured Ingredients

    Vitamin C

    1,500mg  

    Citrus Bioflavonoid Complex

    Grapefruit, lemon, and orange powder

    Elderberry Powder

    Antioxidant properties*

    Quercetin

    50 mg 

    Zinc 

    15 mg

    The modern vitamin C

    High dose of 1,500mg vitamin C, zinc, citrus bioflavonoids with grapefruit, lemon, and orange powders. Features elderberry powder, quercetin, and rosehips extracts.

    Suggested use

    Take 3 capsules daily with 8 ounces of water or your favorite beverage. May be taken with or without food.

    See caution

    CAUTION: Do not exceed recommended dose. Please use caution if you have allergies or sensitivities to any of the listed ingredients. Pregnant or nursing mothers and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Use only as directed. If gastrointestinal discomfort (including bloating, cramps, diarrhea, or other digestive upset) or other sensitivity is experienced stop taking the product immediately. If you are pregnant, nursing, or have a medical condition, please consult with your physician before use. If you have any questions about consuming this dietary supplement, consult with your health care professional before using. If you use prescription drugs or over-the-counter medications, are unaware of your current medical condition or have a pre-existing medical condition(s), consult with your health care professional before using. Discontinue use immediately if you experience any adverse symptoms or reactions while taking this product. Discontinue use 2 weeks prior to surgery. Do not use if your health status is unknown. Do not use if safety seal is damaged or missing. Keep out of reach of children and pets. Store in a cool, dry place, away from heat moisture. Use this product as a food supplement only. Do not use for weight reduction.

    Additional Details

    The modern vitamin C

    High dose of 1,500mg vitamin C, zinc, citrus bioflavonoids with grapefruit, lemon, and orange powders. Features elderberry powder, quercetin, and rosehips extracts.

    See all ingredients

    Ingredients:

    Vitamin C (as Ascorbic Acid), Zinc (as Amino Acid Chelate), Phosphatidylcholine (from Sunflower Lecithin), Alpha Lipoic Acid, Citrus Bioflavonoid Complex: Grapefruit Powder (Fruit), Lemon Powder (Peel), Orange Powder (Fruit), Quercetin Dihydrate, Rosehips Extract (Fruit), Elderberry Powder (Fruit). Other Ingredients: Methylcellulose Capsule.

    Pairs With

    References

    Vitamin C

    Chambial S, Dwivedi S, Shukla KK, John PJ, Sharma P. Vitamin C in disease prevention and cure: an overview. Indian J Clin Biochem. 2013;28(4):314328.  doi: 10.1007/s12291-013-0375-3

    Traber MG, Stevens JF. Vitamins C and E: beneficial effects from a mechanistic perspective. Free Radic Biol Med. 2011;51(5):10001013. doi: 10.1016/j.freeradbiomed.2011.05.017

    See more

    Padayatty, S. J., Katz, A., Wang, Y., Eck, P., Kwon, O., Lee, J. H., Chen, S., Corpe, C., Dutta, A., Dutta, S. K., & Levine, M. (2003). Vitamin C as an antioxidant: evaluation of its role in disease prevention. Journal of the American College of Nutrition, 22(1), 1835. DOI: 10.1080/07315724.2003.10719272

    Pehlivan, Fadime. (2017). Vitamin C: An Antioxidant Agent. 10.5772/intechopen.69660. DOI: 10.5772/intechopen.69660

    A. Bendich, L.J. Machlin, O. Scandurra, G.W. Burton, D.D.M. Wayner, The antioxidant role of vitamin C, Advances in Free Radical Biology & Medicine, Volume 2, Issue 2, 1986, 419-444, 8755-9668. https://doi.org/10.1016/S8755-9668(86)80021-7

    Marc Bürzle, Matthias A. Hediger. Chapter Eleven: Functional and Physiological Role of Vitamin C Transporters. Mark O. Bevensee. Current Topics in Membranes. Academic Press. 70. 2012. 357-375. 1063-5823. 9780123943163. https://doi.org/10.1016/B978-0-12-394316-3.00011-9

    Akbari, Abolfazl & Jelodar, Gholamali & Nazifi, Saeed & Sajedianfard, Javad. (2016). An Overview of The characteristics and Function of Vitamin C in Various Tissues: Relying on its Antioxidant Function. Zahedan Journal of Research in Medical Sciences. In Press. DOI: 10.17795/zjrms-4037

    Chakraborthy, Aratirika & Ramani, Pratibha & Sherlin, Herald & Premkumar, Priya & Natesan, Anuja. (2014). Antioxidant and pro-oxidant activity of Vitamin C in oral environment. Indian journal of dental research : official publication of Indian Society for Dental Research. 25. 499-504. DOI: 10.4103/0970-9290.142547

    Sirmali, Rana & Giniş, Zeynep & Sirmali, Mehmet & Solak, Okan & Şeliman, Bengü & Ağaçkiran, Yetkin & Delibaş, Namık. (2014). Vitamin C as an antioxidant: evaluation of its role on pulmonary contusion experimental model. Turkish journal of medical sciences. 44. 905-13. DOI: 10.3906/sag-1309-139

    Citrus Bioflavonoid Complex

    Stevens, Y., Rymenant, E. V., Grootaert, C., Camp, J. V., Possemiers, S., Masclee, A., & Jonkers, D. (2019). The Intestinal Fate of Citrus Flavanones and Their Effects on Gastrointestinal Health. Nutrients, 11(7), 1464. DOI: 10.3390/nu11071464

    Testai L, Calderone V. Nutraceutical Value of Citrus Flavanones and Their Implications in Cardiovascular Disease. Nutrients. 2017;9(5):502. Published 2017 May 16. doi: 10.3390/nu9050502

    Barreca, D., Gattuso, G., Bellocco, E., Calderaro, A., Trombetta, D., Smeriglio, A., Laganà, G., Daglia, M., Meneghini, S., & Nabavi, S. M. (2017). Flavanones: Citrus phytochemical with health-promoting properties. BioFactors (Oxford, England), 43(4), 495506. DOI: 10.1002/biof.1363

    Sharma, M., Akhtar, N., Sambhav, K., Shete, G., Bansal, A. K., & Sharma, S. S. (2015). Emerging potential of citrus flavanones as an antioxidant in diabetes and its complications. Current topics in medicinal chemistry, 15(2), 187195. DOI: 10.2174/1568026615666141209163013

    Chanet, A., Milenkovic, D., Manach, C., Mazur, A., & Morand, C. (2012). Citrus flavanones: what is their role in cardiovascular protection?. Journal of agricultural and food chemistry, 60(36), 88098822. DOI: 10.1021/jf300669s

    Zaidun, N. H., Thent, Z. C., & Latiff, A. A. (2018). Combating oxidative stress disorders with citrus flavonoid: Naringenin. Life sciences, 208, 111122. DOI: 10.1016/j.lfs.2018.07.017

    Assini, J. M., Mulvihill, E. E., & Huff, M. W. (2013). Citrus flavonoids and lipid metabolism. Current opinion in lipidology, 24(1), 3440. DOI: 10.1097/MOL.0b013e32835c07fd

    Asgary, S., Naderi, G., & Askari, N. (2005). Protective effect of flavonoids against red blood cell hemolysis by free radicals. Experimental and clinical cardiology, 10(2), 8890. PMCID: PMC2716227

    Elderberry Powder

    Sidor, Andrzej & Gramza Michalowska, Anna. (2014). Advanced research on the antioxidant and health benefit of elderberry (Sambucus nigra) in food a review. Journal of Functional Foods. 18. DOI: 10.1016/j.jff.2014.07.012

    Porter, R. S., & Bode, R. F. (2017). A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products. Phytotherapy research : PTR, 31(4), 533554. DOI: 10.1002/ptr.5782

    Zakay-Rones, Z., Thom, E., Wollan, T., & Wadstein, J. (2004). Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections. The Journal of international medical research, 32(2), 132140. DOI: 10.1177/147323000403200205

    Barak, V., Halperin, T., & Kalickman, I. (2001). The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. European cytokine network, 12(2), 290296. PMID: 11399518

    Hawkins, J., Baker, C., Cherry, L., & Dunne, E. (2019). Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials. Complementary therapies in medicine, 42, 361365. DOI: 10.1016/j.ctim.2018.12.004

    Tiralongo E, Wee SS, Lea RA. Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial. Nutrients. 2016;8(4):182. Published 2016 Mar 24. doi: 10.3390/nu8040182

    Porter, R. S., & Bode, R. F. (2017). A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products. Phytotherapy research : PTR, 31(4), 533554. DOI: 10.1002/ptr.5782

    Quercetin

    Selamoglu, Zeliha. (2016). Antioxidant Activity of Quercetin: A Mechanistic Review. Turkish Journal of Agriculture - Food Science and Technology. 4. 10.24925/turjaf.v4i12.1134-1138.1069. DOI: 10.24925/turjaf.v4i12.1134-1138.1069

    Anand David AV, Arulmoli R, Parasuraman S. Overviews of Biological Importance of Quercetin: A Bioactive Flavonoid. Pharmacogn Rev. 2016;10(20):8489. doi: 10.4103/0973-7847.194044

    Serban, M. C., Sahebkar, A., Zanchetti, A., Mikhailidis, D. P., Howard, G., Antal, D., Andrica, F., Ahmed, A., Aronow, W. S., Muntner, P., Lip, G. Y., Graham, I., Wong, N., Rysz, J., Banach, M., & Lipid and Blood Pressure Metaanalysis Collaboration (LBPMC) Group (2016). Effects of Quercetin on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Journal of the American Heart Association, 5(7), e002713. DOI: 10.1161/JAHA.115.002713

    Xu D, Hu MJ, Wang YQ, Cui YL. Antioxidant Activities of Quercetin and Its Complexes for Medicinal Application. Molecules. 2019;24(6):1123. Published 2019 Mar 21. doi: 10.3390/molecules24061123

    Alía, M., Mateos, R., Ramos, S., Lecumberri, E., Bravo, L., & Goya, L. (2006). Influence of quercetin and rutin on growth and antioxidant defense system of a human hepatoma cell line (HepG2). European journal of nutrition, 45(1), 1928. DOI: 10.1007/s00394-005-0558-7

    Robaszkiewicz, A., Balcerczyk, A., & Bartosz, G. (2007). Antioxidative and prooxidative effects of quercetin on A549 cells. Cell biology international, 31(10), 12451250. DOI: 10.1016/j.cellbi.2007.04.009

    Kim, G. N., & Jang, H. D. (2009). Protective mechanism of quercetin and rutin using glutathione metabolism on HO-induced oxidative stress in HepG2 cells. Annals of the New York Academy of Sciences, 1171, 530537. DOI: 10.1111/j.1749-6632.2009.04690.x

    Baghel, Satyendra & Shrivastava, Nikhil & Baghel, PA & Rajput, Sarlesh. (2012). A review of quercetin: Antioxidant and anticancer properties. World J Pharm Pharmaceutical Sci. 1. 146 - 160.

    Zinc 

    Kaltenberg, J., Plum, L. M., Ober-Blöbaum, J. L., Hönscheid, A., Rink, L., & Haase, H. (2010). Zinc signals promote IL-2-dependent proliferation of T cells. European journal of immunology, 40(5), 14961503. DOI: 10.1002/eji.200939574

    Shankar, A. H., & Prasad, A. S. (1998). Zinc and immune function: the biological basis of altered resistance to infection. The American journal of clinical nutrition, 68(2 Suppl), 447S463S. DOI: 10.1093/ajcn/68.2.447S

    Barnett, J. B., Dao, M. C., Hamer, D. H., Kandel, R., Brandeis, G., Wu, D., Dallal, G. E., Jacques, P. F., Schreiber, R., Kong, E., & Meydani, S. N. (2016). Effect of zinc supplementation on serum zinc concentration and T cell proliferation in nursing home elderly: a randomized, double-blind, placebo-controlled trial. The American journal of clinical nutrition, 103(3), 942951. DOI: 10.3945/ajcn.115.115188

    Barnett JB, Hamer DH, Meydani SN. Low zinc status: a new risk factor for pneumonia in the elderly? Nutrition Reviews. 2010 Jan;68(1):30-37. DOI: 10.1111/j.1753-4887.2009.00253.x 

    Yasuda, Hiroshi. (2017). The Situation of Zinc Deficiency: Early Assessment and Intervention Are Essential. Biomedical Research on Trace Elements. 125-140. DOI: 10.11299/brte.27.125

    Hemilä H. Zinc lozenges may shorten the duration of colds: a systematic review. Open Respir Med J. 2011;5:5158. doi: 10.2174/1874306401105010051

    Rerksuppaphol, S., & Rerksuppaphol, L. (2013). A randomized controlled trial of chelated zinc for prevention of the common cold in Thai school children. Paediatrics and international child health, 33(3), 145150. DOI: 10.1179/2046905513Y.0000000064

    [more] Shade CW. Liposomes as Advanced Delivery Systems for Nutraceuticals. Integr Med (Encinitas). 2016;15(1):3336. PMID: 27053934

    Vitamin C (as Ascorbic Acid), Zinc (as Amino Acid Chelate), Phosphatidylcholine (from Sunflower Lecithin), Alpha Lipoic Acid, Citrus Bioflavonoid Complex: Grapefruit Powder (Fruit), Lemon Powder (Peel), Orange Powder (Fruit), Quercetin Dihydrate, Rosehips Extract (Fruit), Elderberry Powder (Fruit). Other Ingredients: Methylcellulose Capsule.

    Take 3 capsules daily with 8 ounces of water or your favorite beverage. May be taken with or without food.

    CAUTION: Do not exceed recommended dose. Please use caution if you have allergies or sensitivities to any of the listed ingredients. Pregnant or nursing mothers and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Use only as directed. If gastrointestinal discomfort (including bloating, cramps, diarrhea, or other digestive upset) or other sensitivity is experienced stop taking the product immediately. If you are pregnant, nursing, or have a medical condition, please consult with your physician before use. If you have any questions about consuming this dietary supplement, consult with your health care professional before using. If you use prescription drugs or over-the-counter medications, are unaware of your current medical condition or have a pre-existing medical condition(s), consult with your health care professional before using. Discontinue use immediately if you experience any adverse symptoms or reactions while taking this product. Discontinue use 2 weeks prior to surgery. Do not use if your health status is unknown. Do not use if safety seal is damaged or missing. Keep out of reach of children and pets. Store in a cool, dry place, away from heat moisture. Use this product as a food supplement only. Do not use for weight reduction.

    Vitamin C

    Chambial S, Dwivedi S, Shukla KK, John PJ, Sharma P. Vitamin C in disease prevention and cure: an overview. Indian J Clin Biochem. 2013;28(4):314328.  doi: 10.1007/s12291-013-0375-3

    Traber MG, Stevens JF. Vitamins C and E: beneficial effects from a mechanistic perspective. Free Radic Biol Med. 2011;51(5):10001013. doi: 10.1016/j.freeradbiomed.2011.05.017

    Padayatty, S. J., Katz, A., Wang, Y., Eck, P., Kwon, O., Lee, J. H., Chen, S., Corpe, C., Dutta, A., Dutta, S. K., & Levine, M. (2003). Vitamin C as an antioxidant: evaluation of its role in disease prevention. Journal of the American College of Nutrition, 22(1), 1835. DOI: 10.1080/07315724.2003.10719272

    Pehlivan, Fadime. (2017). Vitamin C: An Antioxidant Agent. 10.5772/intechopen.69660. DOI: 10.5772/intechopen.69660

    A. Bendich, L.J. Machlin, O. Scandurra, G.W. Burton, D.D.M. Wayner, The antioxidant role of vitamin C, Advances in Free Radical Biology & Medicine, Volume 2, Issue 2, 1986, 419-444, 8755-9668. https://doi.org/10.1016/S8755-9668(86)80021-7

    Marc Bürzle, Matthias A. Hediger. Chapter Eleven: Functional and Physiological Role of Vitamin C Transporters. Mark O. Bevensee. Current Topics in Membranes. Academic Press. 70. 2012. 357-375. 1063-5823. 9780123943163. https://doi.org/10.1016/B978-0-12-394316-3.00011-9

    Akbari, Abolfazl & Jelodar, Gholamali & Nazifi, Saeed & Sajedianfard, Javad. (2016). An Overview of The characteristics and Function of Vitamin C in Various Tissues: Relying on its Antioxidant Function. Zahedan Journal of Research in Medical Sciences. In Press. DOI: 10.17795/zjrms-4037

    Chakraborthy, Aratirika & Ramani, Pratibha & Sherlin, Herald & Premkumar, Priya & Natesan, Anuja. (2014). Antioxidant and pro-oxidant activity of Vitamin C in oral environment. Indian journal of dental research : official publication of Indian Society for Dental Research. 25. 499-504. DOI: 10.4103/0970-9290.142547

    Sirmali, Rana & Giniş, Zeynep & Sirmali, Mehmet & Solak, Okan & Şeliman, Bengü & Ağaçkiran, Yetkin & Delibaş, Namık. (2014). Vitamin C as an antioxidant: evaluation of its role on pulmonary contusion experimental model. Turkish journal of medical sciences. 44. 905-13. DOI: 10.3906/sag-1309-139

    Citrus Bioflavonoid Complex

    Stevens, Y., Rymenant, E. V., Grootaert, C., Camp, J. V., Possemiers, S., Masclee, A., & Jonkers, D. (2019). The Intestinal Fate of Citrus Flavanones and Their Effects on Gastrointestinal Health. Nutrients, 11(7), 1464. DOI: 10.3390/nu11071464

    Testai L, Calderone V. Nutraceutical Value of Citrus Flavanones and Their Implications in Cardiovascular Disease. Nutrients. 2017;9(5):502. Published 2017 May 16. doi: 10.3390/nu9050502

    Barreca, D., Gattuso, G., Bellocco, E., Calderaro, A., Trombetta, D., Smeriglio, A., Laganà, G., Daglia, M., Meneghini, S., & Nabavi, S. M. (2017). Flavanones: Citrus phytochemical with health-promoting properties. BioFactors (Oxford, England), 43(4), 495506. DOI: 10.1002/biof.1363

    Sharma, M., Akhtar, N., Sambhav, K., Shete, G., Bansal, A. K., & Sharma, S. S. (2015). Emerging potential of citrus flavanones as an antioxidant in diabetes and its complications. Current topics in medicinal chemistry, 15(2), 187195. DOI: 10.2174/1568026615666141209163013

    Chanet, A., Milenkovic, D., Manach, C., Mazur, A., & Morand, C. (2012). Citrus flavanones: what is their role in cardiovascular protection?. Journal of agricultural and food chemistry, 60(36), 88098822. DOI: 10.1021/jf300669s

    Zaidun, N. H., Thent, Z. C., & Latiff, A. A. (2018). Combating oxidative stress disorders with citrus flavonoid: Naringenin. Life sciences, 208, 111122. DOI: 10.1016/j.lfs.2018.07.017

    Assini, J. M., Mulvihill, E. E., & Huff, M. W. (2013). Citrus flavonoids and lipid metabolism. Current opinion in lipidology, 24(1), 3440. DOI: 10.1097/MOL.0b013e32835c07fd

    Asgary, S., Naderi, G., & Askari, N. (2005). Protective effect of flavonoids against red blood cell hemolysis by free radicals. Experimental and clinical cardiology, 10(2), 8890. PMCID: PMC2716227

    Elderberry Powder

    Sidor, Andrzej & Gramza Michalowska, Anna. (2014). Advanced research on the antioxidant and health benefit of elderberry (Sambucus nigra) in food a review. Journal of Functional Foods. 18. DOI: 10.1016/j.jff.2014.07.012

    Porter, R. S., & Bode, R. F. (2017). A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products. Phytotherapy research : PTR, 31(4), 533554. DOI: 10.1002/ptr.5782

    Zakay-Rones, Z., Thom, E., Wollan, T., & Wadstein, J. (2004). Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections. The Journal of international medical research, 32(2), 132140. DOI: 10.1177/147323000403200205

    Barak, V., Halperin, T., & Kalickman, I. (2001). The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. European cytokine network, 12(2), 290296. PMID: 11399518

    Hawkins, J., Baker, C., Cherry, L., & Dunne, E. (2019). Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials. Complementary therapies in medicine, 42, 361365. DOI: 10.1016/j.ctim.2018.12.004

    Tiralongo E, Wee SS, Lea RA. Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial. Nutrients. 2016;8(4):182. Published 2016 Mar 24. doi: 10.3390/nu8040182

    Porter, R. S., & Bode, R. F. (2017). A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products. Phytotherapy research : PTR, 31(4), 533554. DOI: 10.1002/ptr.5782

    Quercetin

    Selamoglu, Zeliha. (2016). Antioxidant Activity of Quercetin: A Mechanistic Review. Turkish Journal of Agriculture - Food Science and Technology. 4. 10.24925/turjaf.v4i12.1134-1138.1069. DOI: 10.24925/turjaf.v4i12.1134-1138.1069

    Anand David AV, Arulmoli R, Parasuraman S. Overviews of Biological Importance of Quercetin: A Bioactive Flavonoid. Pharmacogn Rev. 2016;10(20):8489. doi: 10.4103/0973-7847.194044

    Serban, M. C., Sahebkar, A., Zanchetti, A., Mikhailidis, D. P., Howard, G., Antal, D., Andrica, F., Ahmed, A., Aronow, W. S., Muntner, P., Lip, G. Y., Graham, I., Wong, N., Rysz, J., Banach, M., & Lipid and Blood Pressure Metaanalysis Collaboration (LBPMC) Group (2016). Effects of Quercetin on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Journal of the American Heart Association, 5(7), e002713. DOI: 10.1161/JAHA.115.002713

    Xu D, Hu MJ, Wang YQ, Cui YL. Antioxidant Activities of Quercetin and Its Complexes for Medicinal Application. Molecules. 2019;24(6):1123. Published 2019 Mar 21. doi: 10.3390/molecules24061123

    Alía, M., Mateos, R., Ramos, S., Lecumberri, E., Bravo, L., & Goya, L. (2006). Influence of quercetin and rutin on growth and antioxidant defense system of a human hepatoma cell line (HepG2). European journal of nutrition, 45(1), 1928. DOI: 10.1007/s00394-005-0558-7

    Robaszkiewicz, A., Balcerczyk, A., & Bartosz, G. (2007). Antioxidative and prooxidative effects of quercetin on A549 cells. Cell biology international, 31(10), 12451250. DOI: 10.1016/j.cellbi.2007.04.009

    Kim, G. N., & Jang, H. D. (2009). Protective mechanism of quercetin and rutin using glutathione metabolism on HO-induced oxidative stress in HepG2 cells. Annals of the New York Academy of Sciences, 1171, 530537. DOI: 10.1111/j.1749-6632.2009.04690.x

    Baghel, Satyendra & Shrivastava, Nikhil & Baghel, PA & Rajput, Sarlesh. (2012). A review of quercetin: Antioxidant and anticancer properties. World J Pharm Pharmaceutical Sci. 1. 146 - 160.

    Zinc 

    Kaltenberg, J., Plum, L. M., Ober-Blöbaum, J. L., Hönscheid, A., Rink, L., & Haase, H. (2010). Zinc signals promote IL-2-dependent proliferation of T cells. European journal of immunology, 40(5), 14961503. DOI: 10.1002/eji.200939574

    Shankar, A. H., & Prasad, A. S. (1998). Zinc and immune function: the biological basis of altered resistance to infection. The American journal of clinical nutrition, 68(2 Suppl), 447S463S. DOI: 10.1093/ajcn/68.2.447S

    Barnett, J. B., Dao, M. C., Hamer, D. H., Kandel, R., Brandeis, G., Wu, D., Dallal, G. E., Jacques, P. F., Schreiber, R., Kong, E., & Meydani, S. N. (2016). Effect of zinc supplementation on serum zinc concentration and T cell proliferation in nursing home elderly: a randomized, double-blind, placebo-controlled trial. The American journal of clinical nutrition, 103(3), 942951. DOI: 10.3945/ajcn.115.115188

    Barnett JB, Hamer DH, Meydani SN. Low zinc status: a new risk factor for pneumonia in the elderly? Nutrition Reviews. 2010 Jan;68(1):30-37. DOI: 10.1111/j.1753-4887.2009.00253.x 

    Yasuda, Hiroshi. (2017). The Situation of Zinc Deficiency: Early Assessment and Intervention Are Essential. Biomedical Research on Trace Elements. 125-140. DOI: 10.11299/brte.27.125

    Hemilä H. Zinc lozenges may shorten the duration of colds: a systematic review. Open Respir Med J. 2011;5:5158. doi: 10.2174/1874306401105010051

    Rerksuppaphol, S., & Rerksuppaphol, L. (2013). A randomized controlled trial of chelated zinc for prevention of the common cold in Thai school children. Paediatrics and international child health, 33(3), 145150. DOI: 10.1179/2046905513Y.0000000064

    [more] Shade CW. Liposomes as Advanced Delivery Systems for Nutraceuticals. Integr Med (Encinitas). 2016;15(1):3336. PMID: 27053934

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    M
    09/13/2022
    Malatino
    United States

    New Customer

    Issues and shipping are the "BEST" . I have taken Collagen Platinum for a month and notice my shoulder joint pain disappeared but now that i started my second month supply they have returned. As for my skin it has a modest improvement with my arms. I will give it two more months. Optimistic.

    AH
    09/11/2022
    Angie H.
    United States United States

    Great product

    Never disappointed with these products! High quality, Easy on the stomach vitamin! Recommend wholeheartedly!

    FD
    09/11/2022
    Francisco D.
    United States United States

    Wonder-C

    The only vitamin C supplement I use daily. Excellent product.

    KT
    09/07/2022
    Kristen T.
    United States United States

    Vit C

    Very good quality, minimal taste

    A Codeage Customer
    ST
    09/04/2022
    Stephen T.
    United States United States

    Additive free

    One of the underlying premise for taking vitamin supplements is to support your health. Companies that choose to add excipients and binders are disingenuous to this purpose. Codeage C had no (cheap) unnecessary additives. Why deliberately introduce more unneeded additives to our bodies? Thank you Codeage for figuring it out.

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