Vitamina D (como colecalciferol de origen vegetal procedente de líquenes silvestres), zinc (de L-carnosina de zinc), L-glutamina, N-acetilglucosamina vegana, ácido butírico, Saccharomyces boulardii (2,3 mil millones de células probióticas viables), regaliz desglicirricinado (DGL). ) Extracto (raíz) (Glycyrrhiza spp.), Bacillus coagulans (probiótico a base de esporas) (1,2 mil millones de células probióticas viables), corteza de canela (Cinnamomum burmannii) en polvo, extracto de cuerpo fructífero del hongo maitake (Grifola frondoa) (30% polisacáridos), Mezcla concentrada de polifenoles: arándano silvestre orgánico, fresa orgánica, frambuesa orgánica, cereza ácida orgánica, saúco orgánico, arándano rojo orgánico, dihidrato de quercetina, olmo resbaladizo (corteza) (Ulmus rubra), extracto de jengibre (Zingiber officinale), pomelo (Citrus paradisi) Extracto de semilla, flor de manzanilla, extracto de malvavisco (raíz) (Althaea officinalis), berberina (de Berberine HCL), extracto de fruto de pimienta negra BioPerine® (Piper nigrum; estándar a 95 % de piperina). Otros ingredientes: Cápsula de metilcelulosa.

Los adultos toman 2 cápsulas con 8 onzas de agua o su bebida favorita. Puede tomarse con o sin alimentos.

PRECAUCIÓN: No exceda la dosis recomendada. Las mujeres embarazadas, las madres lactantes, los niños menores de 18 años y las personas con una afección médica conocida deben consultar a un médico antes de usar este o cualquier suplemento dietético. Tenga cuidado si tiene alergias o sensibilidades a alguno de los ingredientes enumerados. Mantener fuera del alcance de los niños y las mascotas. No lo utilice si el sello de seguridad está dañado o falta. Guardar en un lugar fresco y seco. Utilice este producto únicamente como complemento alimenticio. No utilice para la reducción de peso.

Soil & Plant Based Prebiotic

Davani-Davari D, Negahdaripour M, Karimzadeh I, et al. Prebiotics: Definition, Types, Sources, Mechanisms, and Clinical Applications. Foods. 2019;8(3):92. Published 2019 Mar 9. doi:10.3390/foods8030092

Justin L Carlson, Jennifer M Erickson, Beate B Lloyd, Joanne L Slavin, Health Effects and Sources of Prebiotic Dietary Fiber, Current Developments in Nutrition, Volume 2, Issue 3, March 2018, nzy005, https://doi.org/10.1093/cdn/nzy005

Glenn R. Gibson, Marcel B. Roberfroid, Dietary Modulation of the Human Colonic Microbiota: Introducing the Concept of Prebiotics, The Journal of Nutrition, Volume 125, Issue 6, June 1995, Pages 1401–1412, https://doi.org/10.1093/jn/125.6.1401

McBurney MI, Davis C, Fraser CM, et al. Establishing What Constitutes a Healthy Human Gut Microbiome: State of the Science, Regulatory Considerations, and Future Directions. J Nutr. 2019;149(11):1882‐1895. doi:10.1093/jn/nxz154

Yadav, S., Jha, R. Strategies to modulate the intestinal microbiota and their effects on nutrient utilization, performance, and health of poultry. J Animal Sci Biotechnol 10, 2 (2019). https://doi.org/10.1186/s40104-018-0310-9

Greta Jakobsdottir, Margareta Nyman, Frida Fåk,Designing future prebiotic fiber to target metabolic syndrome, Nutrition, Volume 30, Issue 5, 2014, Pages 497-502, ISSN 0899-9007, https://doi.org/10.1016/j.nut.2013.08.013.

La Fata G, Rastall RA, Lacroix C, et al. Recent Development of Prebiotic Research-Statement from an Expert Workshop. Nutrients. 2017;9(12):1376. Published 2017 Dec 20. doi:10.3390/nu9121376

Soil & Plant Based Probiotic

Foster, K., Schluter, J., Coyte, K. et al. The evolution of the host microbiome as an ecosystem on a leash. Nature 548, 43–51 (2017). https://doi.org/10.1038/nature23292

Cuentas, Ana & Deaton, John & Khan, Sonaina & Davidson, John & St Clair, Courtney. (2017). The Effect of Bacillus subtilis DE111 on the Daily Bowel Movement Profile for People with Occasional Gastrointestinal Irregularity. Journal of Probiotics & Health. 05. DOI: 10.4172/2329-8901.1000189

Elshaghabee Fouad M. F., Rokana Namita, Gulhane Rohini D., Sharma Chetan, Panwar Harsh, Bacillus As Potential Probiotics: Status, Concerns, and Future Perspectives, Frontiers in Microbiology. 2017; 8: 1490. DOI=10.3389/fmicb.2017.01490

Casula G, Cutting SM. Bacillus probiotics: spore germination in the gastrointestinal tract. Appl Environ Microbiol. 2002;68(5):2344‐2352. doi: 10.1128/AEM.68.5.2344-2352.2002

Bittner AC, Croffut RM, Stranahan MC, Yokelson TN. Prescript-assist probiotic-prebiotic treatment for irritable bowel syndrome: an open-label, partially controlled, 1-year extension of a previously published controlled clinical trial. Clinical Therapeutics. 2007 Jun;29(6):1153-1160. DOI: 10.1016/j.clinthera.2007.06.010

Hun L. Bacillus coagulans significantly improved abdominal pain and bloating in patients with IBS. Postgraduate Medicine. 2009 Mar;121(2):119-124. DOI: 10.3810/pgm.2009.03.1984

L-Glutamine

Cruzat V, Macedo Rogero M, Noel Keane K, Curi R, Newsholme P. Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation. Nutrients. 2018;10(11):1564. Published 2018 Oct 23. doi: 10.3390/nu10111564

Michael Gleeson, Dosing and Efficacy of Glutamine Supplementation in Human Exercise and Sport Training, The Journal of Nutrition, Volume 138, Issue 10, October 2008, Pages 2045S–2049S, DOI: 10.1093/jn/138.10.2045S

Rao R, Samak G. Role of Glutamine in Protection of Intestinal Epithelial Tight Junctions. J Epithel Biol Pharmacol. 2012;5(Suppl 1-M7):47‐54. doi: 10.2174/1875044301205010047

Shah, A.M.; Wang, Z.; Ma, J. Glutamine Metabolism and Its Role in Immunity, a Comprehensive Review. Animals 2020, 10, 326. DOI: 10.3390/ani10020326

Kim H. Glutamine as an immunonutrient. Yonsei Med J. 2011;52(6):892‐897. doi: 10.3349/ymj.2011.52.6.892

Calder, P.C., Yaqoob, P. Glutamine and the immune system. Amino Acids 17, 227–241 (1999). https://doi.org/10.1007/BF01366922

Wang, B., Wu, G., Zhou, Z. et al. Glutamine and intestinal barrier function. Amino Acids 47, 2143–2154 (2015). https://doi.org/10.1007/s00726-014-1773-4

Zinc

Maggini S, Pierre A, Calder PC. Immune Function and Micronutrient Requirements Change over the Life Course. Nutrients. 2018;10(10):1531. Published 2018 Oct 17. doi: 10.3390/nu10101531

Gombart AF, Pierre A, Maggini S. A Review of Micronutrients and the Immune System-Working in Harmony to Reduce the Risk of Infection. Nutrients. 2020;12(1):236. Published 2020 Jan 16. doi: 10.3390/nu12010236

Prasad AS. Zinc in human health: effect of zinc on immune cells. Mol Med. 2008;14(5-6):353‐357. doi: 10.2119/2008-00033.Prasad

Melissa L. Zastrow and Vincent L. Pecoraro. Designing Hydrolytic Zinc Metalloenzymes. Biochemistry 2014 53 (6), 957-978. February 7, 2014. DOI: 10.1021/bi4016617

Technical University of Munich (TUM). "Diet lacking in zinc is detrimental to human, animal health: Even moderate zinc deficiency is bad for digestion." ScienceDaily. ScienceDaily, 9 June 2016.