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- Multi Collagen instant coffee mocha mix with Kona coffee all-in-one
- 5 types of collagen including types I, II, III, V, and X in this collagen coffee creamer
- Boost your morning routine and revitalize your afternoon with a delicious collagen powder supplement that you can mix in hot and color liquids
- Collagen protein can be found in your skin, hair, nails, joints, and bones
- Codeage instant coffee collagen features 18 amino acids
- 5 different food sources including grass-fed and pasture-raised hydrolyzed bovine collagen peptides, organic chicken bone broth, organic beef bone broth, hydrolyzed wild-caught fish collagen peptides, and eggshell membrane collagen
- Gourmet Kona coffee is considered to be one of the best ground, low-acid coffees in the world, and comes from Hawaii
- Simply add one scoop to 8oz of hot water for a delicious collagen coffee - Try it cold! Mix in a blender with ice for a delicious iced coffee treat!
- Low-acid collagen coffee: Kona coffee beans have a low acid profile making them an ideal ingredient for a flavorful collagen coffee drink
- This multi collagen protein peptides formula is non-GMO
- Gluten, dairy, and soy free
- No shellfish
- Only 1g of sugarĀ and 58 calories per serving
- 1-month supply
- Third-party tested
- Manufactured in a cGMP-certified facility in the USA
Description
Product Details
Featured Ingredients
Kona Instant Coffee
Gourmet coffee from Hawaii
Grass-Fed Hydrolyzed Bovine Collagen Peptides
Types 1 & 3 collagen
Organic Chicken Bone Broth
Type 2 collagen
Organic Beef Bone Broth
Collagen of types 1, 2, and 3
Wild Caught Hydrolyzed Fish Collagen
Types 1 & 3 collagen from white fish
Hawaiian coffee beans
The ultimate coffee lover solution. 5 collagen types enriched with the delicious taste of Kona coffee beans, one of the most exclusive coffees in the world. Treat yourself to a wonderfully smooth instant coffee while enjoying your collagen drink!
Suggested use
Adults take 1-2 scoops of Codeage Multi Collagen Peptides Mocha with 8-12 ounces of water or your favorite beverage or as directed by a qualified healthcare practitioner.
CAUTION: Do not exceed recommended dose. DO NOT use this product If you have any allergies or sensitivities to egg, fish or any of the listed ingredients. If gastrointestinal discomfort (including bloating, cramps, diarrhea, or other digestive upset) or other sensitivity is experienced STOP taking the product immediately. Pregnant or nursing mothers and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Use this product as a food supplement only. Do not use for weight reduction.
Additional Details
Hawaiian coffee beans
The ultimate coffee lover solution. 5 collagen types enriched with the delicious taste of Kona coffee beans, one of the most exclusive coffees in the world. Treat yourself to a wonderfully smooth instant coffee while enjoying your collagen drink!
See all ingredients
Ingredients:
Multi-Collagen Complex: Grass-Fed Hydrolyzed Bovine Collagen Peptides, Organic Beef Bone Broth, Organic Chicken Bone Broth, Wild-Caught Hydrolyzed Fish Collagen Peptides, Eggshell Membrane Collagen, Kona Instant Coffee. Other Ingredients: Cocoa Flavoring, Natural Vanilla Flavoring.
Amino acid profile (average milligrams per serving): Alanine 867 mg, Arginine 737 mg, Aspartic Acid 558 mg, Glutamic Acid 979 mg, Glycine 2334 mg, Histidine 73 mg, Hydroxylysine 85 mg, Hydroxyproline 1134 mg, Isoleucine 149 mg, Leucine 285 mg, Lysine 358 mg, Methionine 86 mg, Phenylalanine 189 mg, Proline 1354 mg, Serine 325 mg, Threonine 177 mg, Tyrosine 50 mg, Valine 220 mg. Average milligrams per serving naturally occurring; absolute values may vary. Contains 8 of 9 essential amino acids. Not a significant source of protein. Collagen protein does not count toward the FDA recommended Percent Daily Value for protein because it lacks one essential amino acid: tryptophan. Packaged by weight, not volume. Settling may occur.
Pairs With
References
Kona Instant Coffee
Carlsen MH, Halvorsen BL, Holte K, et al. The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide. Nutr J. 2010;9:3. Published 2010 Jan 22. doi: 10.1186/1475-2891-9-3
Yashin A, Yashin Y, Wang JY, Nemzer B. Antioxidant and Antiradical Activity of Coffee. Antioxidants (Basel). 2013;2(4):230ā245. Published 2013 Oct 15. doi: 10.3390/antiox2040230
See more
Fusco D, Colloca G, Lo Monaco MR, Cesari M. Effects of antioxidant supplementation on the aging process. Clin Interv Aging. 2007;2(3):377ā387. PMCID: PMC2685276
JI, L.L., LEEUWENBURGH, C., LEICHTWEIS, S., GORE, M., FIEBIG, R., HOLLANDER, J. and BEJMA, J. (1998), Oxidative Stress and Aging: Role of Exercise and Its Influences on Antioxidant Systems. Annals of the New York Academy of Sciences, 854: 102-117. DOI: 10.1111/j.1749-6632.1998.tb09896.x
De la Fuente, M. Effects of antioxidants on immune system ageing. Eur J Clin Nutr 56, S5āS8 (2002). DOI: 10.1038/sj.ejcn.1601476
Bonnefoy, M., Drai, J., & Kostka, T. (2002). [Antioxidants to slow aging, facts and perspectives]. Presse medicale, 31 25, 1174-84 .
JOYE K. WILLCOX, SARAH L. ASH & GEORGE L. CATIGNANI (2004) Antioxidants and Prevention of Chronic Disease, Critical Reviews in Food Science and Nutrition, 44:4, 275-295, DOI: 10.1080/10408690490468489
Grass-Fed Hydrolyzed Bovine Collagen Peptides
Vollmer DL, West VA, Lephart ED. Enhancing Skin Health: By Oral Administration of Natural Compounds and Minerals with Implications to the Dermal Microbiome. Int J Mol Sci. 2018;19(10):3059. Published 2018 Oct 7. doi: 10.3390/ijms19103059
Saha A, Alam MJ, Ashraf KU, Mannan A. Computational analysis of bovine alpha-1 collagen sequences. Bioinformation. 2013;9(1):42ā48. doi: 10.6026/97320630009042
LeĆ³n-LĆ³pez A, Morales-PeƱaloza A, MartĆnez-JuĆ”rez VM, Vargas-Torres A, Zeugolis DI, Aguirre-Ćlvarez G. Hydrolyzed Collagen-Sources and Applications. Molecules. 2019;24(22):4031. Published 2019 Nov 7. doi: 10.3390/molecules24224031
K. Henriksen, M.A. Karsdal, in Biochemistry of Collagens, Laminins and Elastin, 2016
Albaugh VL, Mukherjee K, Barbul A. Proline Precursors and Collagen Synthesis: Biochemical Challenges of Nutrient Supplementation and Wound Healing. J Nutr. 2017;147(11):2011ā2017. doi:10.3945/jn.117.256404
Avila RodrĆguez, MI, RodrĆguez Barroso, LG, SĆ”nchez, ML. Collagen: A review on its sources and potential cosmetic applications. J Cosmet. Dermatol. 2018; 17: 20ā 26. DOI: 10.1111/jocd.12450
Paul C, Leser S, Oesser S. Significant Amounts of Functional Collagen Peptides Can Be Incorporated in the Diet While Maintaining Indispensable Amino Acid Balance. Nutrients. 2019;11(5):1079. Published 2019 May 15. doi: 10.3945/jn.117.256404
Proksch, E., Segger, D., Degwert, J., Schunck, M., Zague, V., & Oesser, S. (2014). Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin pharmacology and physiology, 27(1), 47ā55. DOI: 10.1159/000351376
Zdzieblik D, Oesser S, Baumstark MW, Gollhofer A, Kƶnig D. Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcopenic men: a randomised controlled trial. Br J Nutr. 2015;114(8):1237ā1245. doi: 10.1017/S0007114515002810
Organic Chicken Bone Broth
Crowley DC, Lau FC, Sharma P, et al. Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial. Int J Med Sci. 2009;6(6):312ā321. Published 2009 Oct 9. doi: 10.7150/ijms.6.312
Bakilan F, Armagan O, Ozgen M, Tascioglu F, Bolluk O, Alatas O. Effects of Native Type II Collagen Treatment on Knee Osteoarthritis: A Randomized Controlled Trial. Eurasian J Med. 2016;48(2):95ā101. doi: 10.5152/eurasianjmed.2015.15030
Lugo, J.P., Saiyed, Z.M. & Lane, N.E. Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study. Nutr J 15, 14 (2015). DOI: 10.1186/s12937-016-0130-8
Bagchi, D., Misner, B., Bagchi, M., Kothari, S. C., Downs, B. W., Fafard, R. D., & Preuss, H. G. (2002). Effects of orally administered undenatured type II collagen against arthritic inflammatory diseases: a mechanistic exploration. International journal of clinical pharmacology research, 22(3-4), 101ā110.
Zhu, P., Li, X. Y., Wang, H. K., Jia, J. F., Zheng, Z. H., Ding, J., & Fan, C. M. (2007). Oral administration of type-II collagen peptide 250-270 suppresses specific cellular and humoral immune response in collagen-induced arthritis. Clinical immunology (Orlando, Fla.), 122(1), 75ā84. DOI: 10.1016/j.clim.2006.08.004
Barnett, M. L., Kremer, J. M., St Clair, E. W., Clegg, D. O., Furst, D., Weisman, M., Fletcher, M. J., Chasan-Taber, S., Finger, E., Morales, A., Le, C. H., & Trentham, D. E. (1998). Treatment of rheumatoid arthritis with oral type II collagen. Results of a multicenter, double-blind, placebo-controlled trial. Arthritis and rheumatism, 41(2), 290ā297. DOI: 10.1002/1529-0131(199802)41:2<290::AID-ART13>3.0.CO;2-R
Yoshinari, O., Moriyama, H., & Shiojima, Y. (2015). An overview of a novel, water-soluble undenatured type II collagen (NEXT-II). Journal of the American College of Nutrition, 34(3), 255ā262. DOI: 10.1080/07315724.2014.919541
Paul, C., Leser, S., & Oesser, S. (2019). Significant Amounts of Functional Collagen Peptides Can Be Incorporated in the Diet While Maintaining Indispensable Amino Acid Balance. Nutrients, 11(5), 1079. DOI: 10.3390/nu11051079
Darling, A. L., Manders, R., Sahni, S., Zhu, K., Hewitt, C. E., Prince, R. L., Millward, D. J., & Lanham-New, S. A. (2019). Dietary protein and bone health across the life-course: an updated systematic review and meta-analysis over 40 years. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 30(4), 741ā761. DOI: 10.1007/s00198-019-04933-8
Lerman, R. H., Chang, J. L., Konda, V., Desai, A., & Montalto, M. B. (2015). Nutritional Approach for Relief of Joint Discomfort: A 12-week, Open-case Series and Illustrative Case Report. Integrative medicine (Encinitas, Calif.), 14(5), 52ā61. PMCID: PMC4712866
Organic Beef Bone Broth
Di Lullo GA, Sweeney SM, Korkko J, Ala-Kokko L, San Antonio JD. Mapping the ligand-binding sites and disease-associated mutations on the most abundant protein in the human, type I collagen. The Journal of Biological Chemistry. 2002 Feb;277(6):4223-4231. DOI: 10.1074/jbc.M110709200
Xin Liu, Hong Wu, Michael Byrne, Stephen Krane, and Rudolf Jaenisch. Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascularādevelopment. PNAS March 4, 1997 94 (5) 1852-1856. DOI: 10.1073/pnas.94.5.1852
Rebello, C. J., Liu, A. G., Greenway, F. L., & Dhurandhar, N. V. (2013). Dietary strategies to increase satiety. Advances in food and nutrition research, 69, 105ā182. DOI: 10.1016/B978-0-12-410540-9.00003-X
Rubio, I. G., Castro, G., Zanini, A. C., & Medeiros-Neto, G. (2008). Oral ingestion of a hydrolyzed gelatin meal in subjects with normal weight and in obese patients: Postprandial effect on circulating gut peptides, glucose and... Eating and weight disorders : EWD, 13(1), 48ā53. DOI: 10.1007/BF03327784
Veldhorst, M. A., Nieuwenhuizen, A. G., Hochstenbach-Waelen, A., Westerterp, K. R., Engelen, M. P., Brummer, R. J., Deutz, N. E., & Westerterp-Plantenga, M. S. (2009). A breakfast with alpha-lactalbumin, gelatin, or gelatin + TRP lowers energy intake at lunch compared with a breakfast with casein, soy, whey, or whey-GMP. Clinical nutrition (Edinburgh, Scotland), 28(2), 147ā155. DOI: 10.1016/j.clnu.2008.12.003
Hochstenbach-Waelen, A., Westerterp-Plantenga, M. S., Veldhorst, M. A., & Westerterp, K. R. (2009). Single-protein casein and gelatin diets affect energy expenditure similarly but substrate balance and appetite differently in adults. The Journal of nutrition, 139(12), 2285ā2292. DOI: 10.3945/jn.109.110403
Schunck, M., Zague, V., Oesser, S., & Proksch, E. (2015). Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology. Journal of medicinal food, 18(12), 1340ā1348. DOI: 10.1089/jmf.2015.0022
Wild Caught Hydrolyzed Fish Collagen
Sanchez A, Blanco M, Correa B, Perez-Martin RI, Sotelo CG. Effect of Fish Collagen Hydrolysates on Type I Collagen mRNA Levels of Human Dermal Fibroblast Culture. Mar Drugs. 2018;16(5):144. Published 2018 Apr 26. doi: 10.3390/md16050144
Kƶnig D, Oesser S, Scharla S, Zdzieblik D, Gollhofer A. Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women-A Randomized Controlled Study. Nutrients. 2018;10(1):97. Published 2018 Jan 16. doi: 10.3390/nu10010097
PorfĆrio, ElisĆ¢ngela & Fanaro, Gustavo. (2016). Collagen supplementation as a complementary therapy for the prevention and treatment of osteoporosis and osteoarthritis: a systematic review. Revista Brasileira de Geriatria e Gerontologia. 19. 153-164. DOI: 10.1590/1809-9823.2016.14145
De Luca C, Mikhal'chik EV, Suprun MV, Papacharalambous M, Truhanov AI, Korkina LG. Skin Antiageing and Systemic Redox Effects of Supplementation with Marine Collagen Peptides and Plant-Derived Antioxidants: A Single-Blind Case-Control Clinical Study. Oxid Med Cell Longev. 2016;2016:4389410. doi: 10.1155/2016/4389410
Glynis A. A Double-blind, Placebo-controlled Study Evaluating the Efficacy of an Oral Supplement in Women with Self-perceived Thinning Hair. J Clin Aesthet Dermatol. 2012;5(11):28ā34. PMCID: PMC3509882
Proksch, E., Schunck, M., Zague, V., Segger, D., Degwert, J., & Oesser, S. (2014). Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis. Skin pharmacology and physiology, 27(3), 113ā119. DOI: 10.1159/000355523
Proksch, E., Segger, D., Degwert, J., Schunck, M., Zague, V., & Oesser, S. (2014). Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin pharmacology and physiology, 27(1), 47ā55. DOI: 10.1159/000351376
Supplement Facts
Ingredients
Suggested Use
References
Product Details
- Multi Collagen instant coffee mocha mix with Kona coffee all-in-one
- 5 types of collagen including types I, II, III, V, and X in this collagen coffee creamer
- Boost your morning routine and revitalize your afternoon with a delicious collagen powder supplement that you can mix in hot and color liquids
- Collagen protein can be found in your skin, hair, nails, joints, and bones
- Codeage instant coffee collagen features 18 amino acids
- 5 different food sources including grass-fed and pasture-raised hydrolyzed bovine collagen peptides, organic chicken bone broth, organic beef bone broth, hydrolyzed wild-caught fish collagen peptides, and eggshell membrane collagen
- Gourmet Kona coffee is considered to be one of the best ground, low-acid coffees in the world, and comes from Hawaii
- Simply add one scoop to 8oz of hot water for a delicious collagen coffee - Try it cold! Mix in a blender with ice for a delicious iced coffee treat!
- Low-acid collagen coffee: Kona coffee beans have a low acid profile making them an ideal ingredient for a flavorful collagen coffee drink
- This multi collagen protein peptides formula is non-GMO
- Gluten, dairy, and soy free
- No shellfish
- Only 1g of sugarĀ and 58 calories per serving
- 1-month supply
- Third-party tested
- Manufactured in a cGMP-certified facility in the USA
Featured Ingredients
Kona Instant Coffee
Gourmet coffee from Hawaii
Grass-Fed Hydrolyzed Bovine Collagen Peptides
Types 1 & 3 collagen
Organic Chicken Bone Broth
Type 2 collagen
Organic Beef Bone Broth
Collagen of types 1, 2, and 3
Wild Caught Hydrolyzed Fish Collagen
Types 1 & 3 collagen from white fish
Hawaiian coffee beans
The ultimate coffee lover solution. 5 collagen types enriched with the delicious taste of Kona coffee beans, one of the most exclusive coffees in the world. Treat yourself to a wonderfully smooth instant coffee while enjoying your collagen drink!
Suggested use
Adults take 1-2 scoops of Codeage Multi Collagen Peptides Mocha with 8-12 ounces of water or your favorite beverage or as directed by a qualified healthcare practitioner.
CAUTION: Do not exceed recommended dose. DO NOT use this product If you have any allergies or sensitivities to egg, fish or any of the listed ingredients. If gastrointestinal discomfort (including bloating, cramps, diarrhea, or other digestive upset) or other sensitivity is experienced STOP taking the product immediately. Pregnant or nursing mothers and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Use this product as a food supplement only. Do not use for weight reduction.
Additional Details
Hawaiian coffee beans
The ultimate coffee lover solution. 5 collagen types enriched with the delicious taste of Kona coffee beans, one of the most exclusive coffees in the world. Treat yourself to a wonderfully smooth instant coffee while enjoying your collagen drink!
See all ingredients
Ingredients:
Multi-Collagen Complex: Grass-Fed Hydrolyzed Bovine Collagen Peptides, Organic Beef Bone Broth, Organic Chicken Bone Broth, Wild-Caught Hydrolyzed Fish Collagen Peptides, Eggshell Membrane Collagen, Kona Instant Coffee. Other Ingredients: Cocoa Flavoring, Natural Vanilla Flavoring.
Amino acid profile (average milligrams per serving): Alanine 867 mg, Arginine 737 mg, Aspartic Acid 558 mg, Glutamic Acid 979 mg, Glycine 2334 mg, Histidine 73 mg, Hydroxylysine 85 mg, Hydroxyproline 1134 mg, Isoleucine 149 mg, Leucine 285 mg, Lysine 358 mg, Methionine 86 mg, Phenylalanine 189 mg, Proline 1354 mg, Serine 325 mg, Threonine 177 mg, Tyrosine 50 mg, Valine 220 mg. Average milligrams per serving naturally occurring; absolute values may vary. Contains 8 of 9 essential amino acids. Not a significant source of protein. Collagen protein does not count toward the FDA recommended Percent Daily Value for protein because it lacks one essential amino acid: tryptophan. Packaged by weight, not volume. Settling may occur.
Pairs With
References
Kona Instant Coffee
Carlsen MH, Halvorsen BL, Holte K, et al. The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide. Nutr J. 2010;9:3. Published 2010 Jan 22. doi: 10.1186/1475-2891-9-3
Yashin A, Yashin Y, Wang JY, Nemzer B. Antioxidant and Antiradical Activity of Coffee. Antioxidants (Basel). 2013;2(4):230ā245. Published 2013 Oct 15. doi: 10.3390/antiox2040230
See more
Fusco D, Colloca G, Lo Monaco MR, Cesari M. Effects of antioxidant supplementation on the aging process. Clin Interv Aging. 2007;2(3):377ā387. PMCID: PMC2685276
JI, L.L., LEEUWENBURGH, C., LEICHTWEIS, S., GORE, M., FIEBIG, R., HOLLANDER, J. and BEJMA, J. (1998), Oxidative Stress and Aging: Role of Exercise and Its Influences on Antioxidant Systems. Annals of the New York Academy of Sciences, 854: 102-117. DOI: 10.1111/j.1749-6632.1998.tb09896.x
De la Fuente, M. Effects of antioxidants on immune system ageing. Eur J Clin Nutr 56, S5āS8 (2002). DOI: 10.1038/sj.ejcn.1601476
Bonnefoy, M., Drai, J., & Kostka, T. (2002). [Antioxidants to slow aging, facts and perspectives]. Presse medicale, 31 25, 1174-84 .
JOYE K. WILLCOX, SARAH L. ASH & GEORGE L. CATIGNANI (2004) Antioxidants and Prevention of Chronic Disease, Critical Reviews in Food Science and Nutrition, 44:4, 275-295, DOI: 10.1080/10408690490468489
Grass-Fed Hydrolyzed Bovine Collagen Peptides
Vollmer DL, West VA, Lephart ED. Enhancing Skin Health: By Oral Administration of Natural Compounds and Minerals with Implications to the Dermal Microbiome. Int J Mol Sci. 2018;19(10):3059. Published 2018 Oct 7. doi: 10.3390/ijms19103059
Saha A, Alam MJ, Ashraf KU, Mannan A. Computational analysis of bovine alpha-1 collagen sequences. Bioinformation. 2013;9(1):42ā48. doi: 10.6026/97320630009042
LeĆ³n-LĆ³pez A, Morales-PeƱaloza A, MartĆnez-JuĆ”rez VM, Vargas-Torres A, Zeugolis DI, Aguirre-Ćlvarez G. Hydrolyzed Collagen-Sources and Applications. Molecules. 2019;24(22):4031. Published 2019 Nov 7. doi: 10.3390/molecules24224031
K. Henriksen, M.A. Karsdal, in Biochemistry of Collagens, Laminins and Elastin, 2016
Albaugh VL, Mukherjee K, Barbul A. Proline Precursors and Collagen Synthesis: Biochemical Challenges of Nutrient Supplementation and Wound Healing. J Nutr. 2017;147(11):2011ā2017. doi:10.3945/jn.117.256404
Avila RodrĆguez, MI, RodrĆguez Barroso, LG, SĆ”nchez, ML. Collagen: A review on its sources and potential cosmetic applications. J Cosmet. Dermatol. 2018; 17: 20ā 26. DOI: 10.1111/jocd.12450
Paul C, Leser S, Oesser S. Significant Amounts of Functional Collagen Peptides Can Be Incorporated in the Diet While Maintaining Indispensable Amino Acid Balance. Nutrients. 2019;11(5):1079. Published 2019 May 15. doi: 10.3945/jn.117.256404
Proksch, E., Segger, D., Degwert, J., Schunck, M., Zague, V., & Oesser, S. (2014). Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin pharmacology and physiology, 27(1), 47ā55. DOI: 10.1159/000351376
Zdzieblik D, Oesser S, Baumstark MW, Gollhofer A, Kƶnig D. Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcopenic men: a randomised controlled trial. Br J Nutr. 2015;114(8):1237ā1245. doi: 10.1017/S0007114515002810
Organic Chicken Bone Broth
Crowley DC, Lau FC, Sharma P, et al. Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial. Int J Med Sci. 2009;6(6):312ā321. Published 2009 Oct 9. doi: 10.7150/ijms.6.312
Bakilan F, Armagan O, Ozgen M, Tascioglu F, Bolluk O, Alatas O. Effects of Native Type II Collagen Treatment on Knee Osteoarthritis: A Randomized Controlled Trial. Eurasian J Med. 2016;48(2):95ā101. doi: 10.5152/eurasianjmed.2015.15030
Lugo, J.P., Saiyed, Z.M. & Lane, N.E. Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study. Nutr J 15, 14 (2015). DOI: 10.1186/s12937-016-0130-8
Bagchi, D., Misner, B., Bagchi, M., Kothari, S. C., Downs, B. W., Fafard, R. D., & Preuss, H. G. (2002). Effects of orally administered undenatured type II collagen against arthritic inflammatory diseases: a mechanistic exploration. International journal of clinical pharmacology research, 22(3-4), 101ā110.
Zhu, P., Li, X. Y., Wang, H. K., Jia, J. F., Zheng, Z. H., Ding, J., & Fan, C. M. (2007). Oral administration of type-II collagen peptide 250-270 suppresses specific cellular and humoral immune response in collagen-induced arthritis. Clinical immunology (Orlando, Fla.), 122(1), 75ā84. DOI: 10.1016/j.clim.2006.08.004
Barnett, M. L., Kremer, J. M., St Clair, E. W., Clegg, D. O., Furst, D., Weisman, M., Fletcher, M. J., Chasan-Taber, S., Finger, E., Morales, A., Le, C. H., & Trentham, D. E. (1998). Treatment of rheumatoid arthritis with oral type II collagen. Results of a multicenter, double-blind, placebo-controlled trial. Arthritis and rheumatism, 41(2), 290ā297. DOI: 10.1002/1529-0131(199802)41:2<290::AID-ART13>3.0.CO;2-R
Yoshinari, O., Moriyama, H., & Shiojima, Y. (2015). An overview of a novel, water-soluble undenatured type II collagen (NEXT-II). Journal of the American College of Nutrition, 34(3), 255ā262. DOI: 10.1080/07315724.2014.919541
Paul, C., Leser, S., & Oesser, S. (2019). Significant Amounts of Functional Collagen Peptides Can Be Incorporated in the Diet While Maintaining Indispensable Amino Acid Balance. Nutrients, 11(5), 1079. DOI: 10.3390/nu11051079
Darling, A. L., Manders, R., Sahni, S., Zhu, K., Hewitt, C. E., Prince, R. L., Millward, D. J., & Lanham-New, S. A. (2019). Dietary protein and bone health across the life-course: an updated systematic review and meta-analysis over 40 years. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 30(4), 741ā761. DOI: 10.1007/s00198-019-04933-8
Lerman, R. H., Chang, J. L., Konda, V., Desai, A., & Montalto, M. B. (2015). Nutritional Approach for Relief of Joint Discomfort: A 12-week, Open-case Series and Illustrative Case Report. Integrative medicine (Encinitas, Calif.), 14(5), 52ā61. PMCID: PMC4712866
Organic Beef Bone Broth
Di Lullo GA, Sweeney SM, Korkko J, Ala-Kokko L, San Antonio JD. Mapping the ligand-binding sites and disease-associated mutations on the most abundant protein in the human, type I collagen. The Journal of Biological Chemistry. 2002 Feb;277(6):4223-4231. DOI: 10.1074/jbc.M110709200
Xin Liu, Hong Wu, Michael Byrne, Stephen Krane, and Rudolf Jaenisch. Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascularādevelopment. PNAS March 4, 1997 94 (5) 1852-1856. DOI: 10.1073/pnas.94.5.1852
Rebello, C. J., Liu, A. G., Greenway, F. L., & Dhurandhar, N. V. (2013). Dietary strategies to increase satiety. Advances in food and nutrition research, 69, 105ā182. DOI: 10.1016/B978-0-12-410540-9.00003-X
Rubio, I. G., Castro, G., Zanini, A. C., & Medeiros-Neto, G. (2008). Oral ingestion of a hydrolyzed gelatin meal in subjects with normal weight and in obese patients: Postprandial effect on circulating gut peptides, glucose and... Eating and weight disorders : EWD, 13(1), 48ā53. DOI: 10.1007/BF03327784
Veldhorst, M. A., Nieuwenhuizen, A. G., Hochstenbach-Waelen, A., Westerterp, K. R., Engelen, M. P., Brummer, R. J., Deutz, N. E., & Westerterp-Plantenga, M. S. (2009). A breakfast with alpha-lactalbumin, gelatin, or gelatin + TRP lowers energy intake at lunch compared with a breakfast with casein, soy, whey, or whey-GMP. Clinical nutrition (Edinburgh, Scotland), 28(2), 147ā155. DOI: 10.1016/j.clnu.2008.12.003
Hochstenbach-Waelen, A., Westerterp-Plantenga, M. S., Veldhorst, M. A., & Westerterp, K. R. (2009). Single-protein casein and gelatin diets affect energy expenditure similarly but substrate balance and appetite differently in adults. The Journal of nutrition, 139(12), 2285ā2292. DOI: 10.3945/jn.109.110403
Schunck, M., Zague, V., Oesser, S., & Proksch, E. (2015). Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology. Journal of medicinal food, 18(12), 1340ā1348. DOI: 10.1089/jmf.2015.0022
Wild Caught Hydrolyzed Fish Collagen
Sanchez A, Blanco M, Correa B, Perez-Martin RI, Sotelo CG. Effect of Fish Collagen Hydrolysates on Type I Collagen mRNA Levels of Human Dermal Fibroblast Culture. Mar Drugs. 2018;16(5):144. Published 2018 Apr 26. doi: 10.3390/md16050144
Kƶnig D, Oesser S, Scharla S, Zdzieblik D, Gollhofer A. Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women-A Randomized Controlled Study. Nutrients. 2018;10(1):97. Published 2018 Jan 16. doi: 10.3390/nu10010097
PorfĆrio, ElisĆ¢ngela & Fanaro, Gustavo. (2016). Collagen supplementation as a complementary therapy for the prevention and treatment of osteoporosis and osteoarthritis: a systematic review. Revista Brasileira de Geriatria e Gerontologia. 19. 153-164. DOI: 10.1590/1809-9823.2016.14145
De Luca C, Mikhal'chik EV, Suprun MV, Papacharalambous M, Truhanov AI, Korkina LG. Skin Antiageing and Systemic Redox Effects of Supplementation with Marine Collagen Peptides and Plant-Derived Antioxidants: A Single-Blind Case-Control Clinical Study. Oxid Med Cell Longev. 2016;2016:4389410. doi: 10.1155/2016/4389410
Glynis A. A Double-blind, Placebo-controlled Study Evaluating the Efficacy of an Oral Supplement in Women with Self-perceived Thinning Hair. J Clin Aesthet Dermatol. 2012;5(11):28ā34. PMCID: PMC3509882
Proksch, E., Schunck, M., Zague, V., Segger, D., Degwert, J., & Oesser, S. (2014). Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis. Skin pharmacology and physiology, 27(3), 113ā119. DOI: 10.1159/000355523
Proksch, E., Segger, D., Degwert, J., Schunck, M., Zague, V., & Oesser, S. (2014). Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin pharmacology and physiology, 27(1), 47ā55. DOI: 10.1159/000351376
Multi-Collagen Complex: Grass-Fed Hydrolyzed Bovine Collagen Peptides, Organic Beef Bone Broth, Organic Chicken Bone Broth, Wild-Caught Hydrolyzed Fish Collagen Peptides, Eggshell Membrane Collagen, Kona Instant Coffee. Other Ingredients: Cocoa Flavoring, Natural Vanilla Flavoring.
Amino acid profile (average milligrams per serving): Alanine 867 mg, Arginine 737 mg, Aspartic Acid 558 mg, Glutamic Acid 979 mg, Glycine 2334 mg, Histidine 73 mg, Hydroxylysine 85 mg, Hydroxyproline 1134 mg, Isoleucine 149 mg, Leucine 285 mg, Lysine 358 mg, Methionine 86 mg, Phenylalanine 189 mg, Proline 1354 mg, Serine 325 mg, Threonine 177 mg, Tyrosine 50 mg, Valine 220 mg. Average milligrams per serving naturally occurring; absolute values may vary. Contains 8 of 9 essential amino acids. Not a significant source of protein. Collagen protein does not count toward the FDA recommended Percent Daily Value for protein because it lacks one essential amino acid: tryptophan. Packaged by weight, not volume. Settling may occur.
Adults take 1-2 scoops of Codeage Multi Collagen Peptides Mocha with 8-12 ounces of water or your favorite beverage or as directed by a qualified healthcare practitioner.
CAUTION: Do not exceed recommended dose. DO NOT use this product If you have any allergies or sensitivities to egg, fish or any of the listed ingredients. If gastrointestinal discomfort (including bloating, cramps, diarrhea, or other digestive upset) or other sensitivity is experienced STOP taking the product immediately. Pregnant or nursing mothers and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Use this product as a food supplement only. Do not use for weight reduction.
Kona Instant Coffee
Carlsen MH, Halvorsen BL, Holte K, et al. The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide. Nutr J. 2010;9:3. Published 2010 Jan 22. doi: 10.1186/1475-2891-9-3
Yashin A, Yashin Y, Wang JY, Nemzer B. Antioxidant and Antiradical Activity of Coffee. Antioxidants (Basel). 2013;2(4):230ā245. Published 2013 Oct 15. doi: 10.3390/antiox2040230
Fusco D, Colloca G, Lo Monaco MR, Cesari M. Effects of antioxidant supplementation on the aging process. Clin Interv Aging. 2007;2(3):377ā387. PMCID: PMC2685276
JI, L.L., LEEUWENBURGH, C., LEICHTWEIS, S., GORE, M., FIEBIG, R., HOLLANDER, J. and BEJMA, J. (1998), Oxidative Stress and Aging: Role of Exercise and Its Influences on Antioxidant Systems. Annals of the New York Academy of Sciences, 854: 102-117. DOI: 10.1111/j.1749-6632.1998.tb09896.x
De la Fuente, M. Effects of antioxidants on immune system ageing. Eur J Clin Nutr 56, S5āS8 (2002). DOI: 10.1038/sj.ejcn.1601476
Bonnefoy, M., Drai, J., & Kostka, T. (2002). [Antioxidants to slow aging, facts and perspectives]. Presse medicale, 31 25, 1174-84 .
JOYE K. WILLCOX, SARAH L. ASH & GEORGE L. CATIGNANI (2004) Antioxidants and Prevention of Chronic Disease, Critical Reviews in Food Science and Nutrition, 44:4, 275-295, DOI: 10.1080/10408690490468489
Grass-Fed Hydrolyzed Bovine Collagen Peptides
Vollmer DL, West VA, Lephart ED. Enhancing Skin Health: By Oral Administration of Natural Compounds and Minerals with Implications to the Dermal Microbiome. Int J Mol Sci. 2018;19(10):3059. Published 2018 Oct 7. doi: 10.3390/ijms19103059
Saha A, Alam MJ, Ashraf KU, Mannan A. Computational analysis of bovine alpha-1 collagen sequences. Bioinformation. 2013;9(1):42ā48. doi: 10.6026/97320630009042
LeĆ³n-LĆ³pez A, Morales-PeƱaloza A, MartĆnez-JuĆ”rez VM, Vargas-Torres A, Zeugolis DI, Aguirre-Ćlvarez G. Hydrolyzed Collagen-Sources and Applications. Molecules. 2019;24(22):4031. Published 2019 Nov 7. doi: 10.3390/molecules24224031
K. Henriksen, M.A. Karsdal, in Biochemistry of Collagens, Laminins and Elastin, 2016
Albaugh VL, Mukherjee K, Barbul A. Proline Precursors and Collagen Synthesis: Biochemical Challenges of Nutrient Supplementation and Wound Healing. J Nutr. 2017;147(11):2011ā2017. doi:10.3945/jn.117.256404
Avila RodrĆguez, MI, RodrĆguez Barroso, LG, SĆ”nchez, ML. Collagen: A review on its sources and potential cosmetic applications. J Cosmet. Dermatol. 2018; 17: 20ā 26. DOI: 10.1111/jocd.12450
Paul C, Leser S, Oesser S. Significant Amounts of Functional Collagen Peptides Can Be Incorporated in the Diet While Maintaining Indispensable Amino Acid Balance. Nutrients. 2019;11(5):1079. Published 2019 May 15. doi: 10.3945/jn.117.256404
Proksch, E., Segger, D., Degwert, J., Schunck, M., Zague, V., & Oesser, S. (2014). Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin pharmacology and physiology, 27(1), 47ā55. DOI: 10.1159/000351376
Zdzieblik D, Oesser S, Baumstark MW, Gollhofer A, Kƶnig D. Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcopenic men: a randomised controlled trial. Br J Nutr. 2015;114(8):1237ā1245. doi: 10.1017/S0007114515002810
Organic Chicken Bone Broth
Crowley DC, Lau FC, Sharma P, et al. Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial. Int J Med Sci. 2009;6(6):312ā321. Published 2009 Oct 9. doi: 10.7150/ijms.6.312
Bakilan F, Armagan O, Ozgen M, Tascioglu F, Bolluk O, Alatas O. Effects of Native Type II Collagen Treatment on Knee Osteoarthritis: A Randomized Controlled Trial. Eurasian J Med. 2016;48(2):95ā101. doi: 10.5152/eurasianjmed.2015.15030
Lugo, J.P., Saiyed, Z.M. & Lane, N.E. Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study. Nutr J 15, 14 (2015). DOI: 10.1186/s12937-016-0130-8
Bagchi, D., Misner, B., Bagchi, M., Kothari, S. C., Downs, B. W., Fafard, R. D., & Preuss, H. G. (2002). Effects of orally administered undenatured type II collagen against arthritic inflammatory diseases: a mechanistic exploration. International journal of clinical pharmacology research, 22(3-4), 101ā110.
Zhu, P., Li, X. Y., Wang, H. K., Jia, J. F., Zheng, Z. H., Ding, J., & Fan, C. M. (2007). Oral administration of type-II collagen peptide 250-270 suppresses specific cellular and humoral immune response in collagen-induced arthritis. Clinical immunology (Orlando, Fla.), 122(1), 75ā84. DOI: 10.1016/j.clim.2006.08.004
Barnett, M. L., Kremer, J. M., St Clair, E. W., Clegg, D. O., Furst, D., Weisman, M., Fletcher, M. J., Chasan-Taber, S., Finger, E., Morales, A., Le, C. H., & Trentham, D. E. (1998). Treatment of rheumatoid arthritis with oral type II collagen. Results of a multicenter, double-blind, placebo-controlled trial. Arthritis and rheumatism, 41(2), 290ā297. DOI: 10.1002/1529-0131(199802)41:2<290::AID-ART13>3.0.CO;2-R
Yoshinari, O., Moriyama, H., & Shiojima, Y. (2015). An overview of a novel, water-soluble undenatured type II collagen (NEXT-II). Journal of the American College of Nutrition, 34(3), 255ā262. DOI: 10.1080/07315724.2014.919541
Paul, C., Leser, S., & Oesser, S. (2019). Significant Amounts of Functional Collagen Peptides Can Be Incorporated in the Diet While Maintaining Indispensable Amino Acid Balance. Nutrients, 11(5), 1079. DOI: 10.3390/nu11051079
Darling, A. L., Manders, R., Sahni, S., Zhu, K., Hewitt, C. E., Prince, R. L., Millward, D. J., & Lanham-New, S. A. (2019). Dietary protein and bone health across the life-course: an updated systematic review and meta-analysis over 40 years. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 30(4), 741ā761. DOI: 10.1007/s00198-019-04933-8
Lerman, R. H., Chang, J. L., Konda, V., Desai, A., & Montalto, M. B. (2015). Nutritional Approach for Relief of Joint Discomfort: A 12-week, Open-case Series and Illustrative Case Report. Integrative medicine (Encinitas, Calif.), 14(5), 52ā61. PMCID: PMC4712866
Organic Beef Bone Broth
Di Lullo GA, Sweeney SM, Korkko J, Ala-Kokko L, San Antonio JD. Mapping the ligand-binding sites and disease-associated mutations on the most abundant protein in the human, type I collagen. The Journal of Biological Chemistry. 2002 Feb;277(6):4223-4231. DOI: 10.1074/jbc.M110709200
Xin Liu, Hong Wu, Michael Byrne, Stephen Krane, and Rudolf Jaenisch. Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascularādevelopment. PNAS March 4, 1997 94 (5) 1852-1856. DOI: 10.1073/pnas.94.5.1852
Rebello, C. J., Liu, A. G., Greenway, F. L., & Dhurandhar, N. V. (2013). Dietary strategies to increase satiety. Advances in food and nutrition research, 69, 105ā182. DOI: 10.1016/B978-0-12-410540-9.00003-X
Rubio, I. G., Castro, G., Zanini, A. C., & Medeiros-Neto, G. (2008). Oral ingestion of a hydrolyzed gelatin meal in subjects with normal weight and in obese patients: Postprandial effect on circulating gut peptides, glucose and... Eating and weight disorders : EWD, 13(1), 48ā53. DOI: 10.1007/BF03327784
Veldhorst, M. A., Nieuwenhuizen, A. G., Hochstenbach-Waelen, A., Westerterp, K. R., Engelen, M. P., Brummer, R. J., Deutz, N. E., & Westerterp-Plantenga, M. S. (2009). A breakfast with alpha-lactalbumin, gelatin, or gelatin + TRP lowers energy intake at lunch compared with a breakfast with casein, soy, whey, or whey-GMP. Clinical nutrition (Edinburgh, Scotland), 28(2), 147ā155. DOI: 10.1016/j.clnu.2008.12.003
Hochstenbach-Waelen, A., Westerterp-Plantenga, M. S., Veldhorst, M. A., & Westerterp, K. R. (2009). Single-protein casein and gelatin diets affect energy expenditure similarly but substrate balance and appetite differently in adults. The Journal of nutrition, 139(12), 2285ā2292. DOI: 10.3945/jn.109.110403
Schunck, M., Zague, V., Oesser, S., & Proksch, E. (2015). Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology. Journal of medicinal food, 18(12), 1340ā1348. DOI: 10.1089/jmf.2015.0022
Wild Caught Hydrolyzed Fish Collagen
Sanchez A, Blanco M, Correa B, Perez-Martin RI, Sotelo CG. Effect of Fish Collagen Hydrolysates on Type I Collagen mRNA Levels of Human Dermal Fibroblast Culture. Mar Drugs. 2018;16(5):144. Published 2018 Apr 26. doi: 10.3390/md16050144
Kƶnig D, Oesser S, Scharla S, Zdzieblik D, Gollhofer A. Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women-A Randomized Controlled Study. Nutrients. 2018;10(1):97. Published 2018 Jan 16. doi: 10.3390/nu10010097
PorfĆrio, ElisĆ¢ngela & Fanaro, Gustavo. (2016). Collagen supplementation as a complementary therapy for the prevention and treatment of osteoporosis and osteoarthritis: a systematic review. Revista Brasileira de Geriatria e Gerontologia. 19. 153-164. DOI: 10.1590/1809-9823.2016.14145
De Luca C, Mikhal'chik EV, Suprun MV, Papacharalambous M, Truhanov AI, Korkina LG. Skin Antiageing and Systemic Redox Effects of Supplementation with Marine Collagen Peptides and Plant-Derived Antioxidants: A Single-Blind Case-Control Clinical Study. Oxid Med Cell Longev. 2016;2016:4389410. doi: 10.1155/2016/4389410
Glynis A. A Double-blind, Placebo-controlled Study Evaluating the Efficacy of an Oral Supplement in Women with Self-perceived Thinning Hair. J Clin Aesthet Dermatol. 2012;5(11):28ā34. PMCID: PMC3509882
Proksch, E., Schunck, M., Zague, V., Segger, D., Degwert, J., & Oesser, S. (2014). Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis. Skin pharmacology and physiology, 27(3), 113ā119. DOI: 10.1159/000355523
Proksch, E., Segger, D., Degwert, J., Schunck, M., Zague, V., & Oesser, S. (2014). Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin pharmacology and physiology, 27(1), 47ā55. DOI: 10.1159/000351376
