Zoom Amen Vitamin C Citrus Bioflavonoids Capsules Supplement

Amen Vitamin C+

Vitamin C, Zinc, And Citrus Bioflavonoids All-In-One
    $22.99
    16 reviews
    Vitamin C Complex

    Description

    Product Details

    • 1285 mg of vitamin C
    • 15 mg of zinc
    • Bioflavonoids: this daily vitamin c formula features citrus bioflavonoids, including grapefruit, lemon, and orange powders
    • Elderberry extract
    • Quercetin
    • Rose hips extract fruit
    • Vegan
    • Veggie capsules
    • Milk, wheat & soy-free
    • Paleo & keto friendly
    • Non-GMO and gluten-free
    • 2-month supply
    • Manufactured in the USA in a cGMP facility
    • Third-party tested

    Featured Ingredients

    Vitamin C Complex

    1285 mg

    Citrus Bioflavonoids

    Grapefruit, lemon and orange powders

    Elderberry Powder

    A source of vitamins

    Quercetin

    Flavonoid & plant pigment

    Zinc

    15 mg

    2 months supply

    Vegan and non-GMO Vitamin C capsule solution featuring citrus bioflavonoids, quercetin, rose hips, elderberry extracts, and zinc all-in-one.

    Suggested use

    Adults take 2 capsules daily with 8 ounces of water or your favorite beverage.  May be taken with or without food.

    See caution

    CAUTION: Do not exceed recommended dose. Please use caution if you have allergies or sensitivities to any of the listed ingredients. Pregnant or nursing mothers and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Use only as directed. If gastrointestinal discomfort (including bloating, cramps, diarrhea, or other digestive upset) or other sensitivity is experienced stop taking the product immediately. If you are pregnant, nursing, or have a medical condition, please consult with your physician before use. If you have any questions about consuming this dietary supplement, consult with your health care professional before using. If you use prescription drugs or over-the-counter medications, are unaware of your current medical condition or have a pre-existing medical condition(s), consult with your health care professional before using. Discontinue use immediately if you experience any adverse symptoms or reactions while taking this product. Discontinue use 2 weeks prior to surgery. Do not use if your health status is unknown. Do not use if safety seal is damaged or missing. Keep out of reach of children and pets. Store in a cool, dry place, away from heat moisture. Use this product as a food supplement only. Do not use for weight reduction.

    Additional Details

    2 months supply

    Vegan and non-GMO Vitamin C capsule solution featuring citrus bioflavonoids, quercetin, rose hips, elderberry extracts, and zinc all-in-one.

    See all ingredients

    Ingredients:

    Vitamin C (as Ascorbic Acid), Zinc (as Zinc Amino Acid Chelate), Citrus Bioflavonoid Complex: Grapefruit Powder (Fruit), Lemon Powder (Peel), Orange Powder (Fruit), Quercetin Dihydrate, Rose Hips Extract (Fruit), Elderberry Extract (Fruit; Std. to 5% Flavanoids). Other Ingredients: Methylcellulose Capsule.

    Pairs With

    References

    Vitamin C Complex

    Chambial S, Dwivedi S, Shukla KK, John PJ, Sharma P. Vitamin C in disease prevention and cure: an overview. Indian J Clin Biochem. 2013;28(4):314328.  doi: 10.1007/s12291-013-0375-3

    Traber MG, Stevens JF. Vitamins C and E: beneficial effects from a mechanistic perspective. Free Radic Biol Med. 2011;51(5):10001013. doi: 10.1016/j.freeradbiomed.2011.05.017

    See more

    Padayatty, S. J., Katz, A., Wang, Y., Eck, P., Kwon, O., Lee, J. H., Chen, S., Corpe, C., Dutta, A., Dutta, S. K., & Levine, M. (2003). Vitamin C as an antioxidant: evaluation of its role in disease prevention. Journal of the American College of Nutrition, 22(1), 1835. DOI: 10.1080/07315724.2003.10719272

    Pehlivan, Fadime. (2017). Vitamin C: An Antioxidant Agent. 10.5772/intechopen.69660. DOI: 10.5772/intechopen.69660

    A. Bendich, L.J. Machlin, O. Scandurra, G.W. Burton, D.D.M. Wayner, The antioxidant role of vitamin C, Advances in Free Radical Biology & Medicine, Volume 2, Issue 2, 1986, 419-444, 8755-9668. https://doi.org/10.1016/S8755-9668(86)80021-7

    Marc Bürzle, Matthias A. Hediger. Chapter Eleven: Functional and Physiological Role of Vitamin C Transporters. Mark O. Bevensee. Current Topics in Membranes. Academic Press. 70. 2012. 357-375. 1063-5823. 9780123943163. https://doi.org/10.1016/B978-0-12-394316-3.00011-9

    Akbari, Abolfazl & Jelodar, Gholamali & Nazifi, Saeed & Sajedianfard, Javad. (2016). An Overview of The characteristics and Function of Vitamin C in Various Tissues: Relying on its Antioxidant Function. Zahedan Journal of Research in Medical Sciences. In Press. DOI: 10.17795/zjrms-4037

    Chakraborthy, Aratirika & Ramani, Pratibha & Sherlin, Herald & Premkumar, Priya & Natesan, Anuja. (2014). Antioxidant and pro-oxidant activity of Vitamin C in oral environment. Indian journal of dental research : official publication of Indian Society for Dental Research. 25. 499-504. DOI: 10.4103/0970-9290.142547

    Sirmali, Rana & Giniş, Zeynep & Sirmali, Mehmet & Solak, Okan & Şeliman, Bengü & Ağaçkiran, Yetkin & Delibaş, Namık. (2014). Vitamin C as an antioxidant: evaluation of its role on pulmonary contusion experimental model. Turkish journal of medical sciences. 44. 905-13. DOI: 10.3906/sag-1309-139

    Citrus Bioflavonoids

    Stevens, Y., Rymenant, E. V., Grootaert, C., Camp, J. V., Possemiers, S., Masclee, A., & Jonkers, D. (2019). The Intestinal Fate of Citrus Flavanones and Their Effects on Gastrointestinal Health. Nutrients, 11(7), 1464. DOI: 10.3390/nu11071464

    Testai L, Calderone V. Nutraceutical Value of Citrus Flavanones and Their Implications in Cardiovascular Disease. Nutrients. 2017;9(5):502. Published 2017 May 16. doi: 10.3390/nu9050502

    Barreca, D., Gattuso, G., Bellocco, E., Calderaro, A., Trombetta, D., Smeriglio, A., Laganà, G., Daglia, M., Meneghini, S., & Nabavi, S. M. (2017). Flavanones: Citrus phytochemical with health-promoting properties. BioFactors (Oxford, England), 43(4), 495506. DOI: 10.1002/biof.1363

    Sharma, M., Akhtar, N., Sambhav, K., Shete, G., Bansal, A. K., & Sharma, S. S. (2015). Emerging potential of citrus flavanones as an antioxidant in diabetes and its complications. Current topics in medicinal chemistry, 15(2), 187195. DOI: 10.2174/1568026615666141209163013

    Chanet, A., Milenkovic, D., Manach, C., Mazur, A., & Morand, C. (2012). Citrus flavanones: what is their role in cardiovascular protection?. Journal of agricultural and food chemistry, 60(36), 88098822. DOI: 10.1021/jf300669s

    Zaidun, N. H., Thent, Z. C., & Latiff, A. A. (2018). Combating oxidative stress disorders with citrus flavonoid: Naringenin. Life sciences, 208, 111122. DOI: 10.1016/j.lfs.2018.07.017

    Assini, J. M., Mulvihill, E. E., & Huff, M. W. (2013). Citrus flavonoids and lipid metabolism. Current opinion in lipidology, 24(1), 3440. DOI: 10.1097/MOL.0b013e32835c07fd

    Asgary, S., Naderi, G., & Askari, N. (2005). Protective effect of flavonoids against red blood cell hemolysis by free radicals. Experimental and clinical cardiology, 10(2), 8890. PMCID: PMC2716227

    Elderberry Powder

    Sidor, Andrzej & Gramza Michalowska, Anna. (2014). Advanced research on the antioxidant and health benefit of elderberry (Sambucus nigra) in food a review. Journal of Functional Foods. 18. DOI: 10.1016/j.jff.2014.07.012

    Porter, R. S., & Bode, R. F. (2017). A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products. Phytotherapy research : PTR, 31(4), 533554. DOI: 10.1002/ptr.5782

    Zakay-Rones, Z., Thom, E., Wollan, T., & Wadstein, J. (2004). Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections. The Journal of international medical research, 32(2), 132140. DOI: 10.1177/147323000403200205

    Barak, V., Halperin, T., & Kalickman, I. (2001). The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. European cytokine network, 12(2), 290296. PMID: 11399518

    Hawkins, J., Baker, C., Cherry, L., & Dunne, E. (2019). Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials. Complementary therapies in medicine, 42, 361365. DOI: 10.1016/j.ctim.2018.12.004

    Tiralongo E, Wee SS, Lea RA. Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial. Nutrients. 2016;8(4):182. Published 2016 Mar 24. doi: 10.3390/nu8040182

    Porter, R. S., & Bode, R. F. (2017). A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products. Phytotherapy research : PTR, 31(4), 533554. DOI: 10.1002/ptr.5782

    Quercetin

    Selamoglu, Zeliha. (2016). Antioxidant Activity of Quercetin: A Mechanistic Review. Turkish Journal of Agriculture - Food Science and Technology. 4. 10.24925/turjaf.v4i12.1134-1138.1069. DOI: 10.24925/turjaf.v4i12.1134-1138.1069

    Anand David AV, Arulmoli R, Parasuraman S. Overviews of Biological Importance of Quercetin: A Bioactive Flavonoid. Pharmacogn Rev. 2016;10(20):8489. doi: 10.4103/0973-7847.194044

    Serban, M. C., Sahebkar, A., Zanchetti, A., Mikhailidis, D. P., Howard, G., Antal, D., Andrica, F., Ahmed, A., Aronow, W. S., Muntner, P., Lip, G. Y., Graham, I., Wong, N., Rysz, J., Banach, M., & Lipid and Blood Pressure Metaanalysis Collaboration (LBPMC) Group (2016). Effects of Quercetin on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Journal of the American Heart Association, 5(7), e002713. DOI: 10.1161/JAHA.115.002713

    Xu D, Hu MJ, Wang YQ, Cui YL. Antioxidant Activities of Quercetin and Its Complexes for Medicinal Application. Molecules. 2019;24(6):1123. Published 2019 Mar 21. doi: 10.3390/molecules24061123

    Alía, M., Mateos, R., Ramos, S., Lecumberri, E., Bravo, L., & Goya, L. (2006). Influence of quercetin and rutin on growth and antioxidant defense system of a human hepatoma cell line (HepG2). European journal of nutrition, 45(1), 1928. DOI: 10.1007/s00394-005-0558-7

    Robaszkiewicz, A., Balcerczyk, A., & Bartosz, G. (2007). Antioxidative and prooxidative effects of quercetin on A549 cells. Cell biology international, 31(10), 12451250. DOI: 10.1016/j.cellbi.2007.04.009

    Kim, G. N., & Jang, H. D. (2009). Protective mechanism of quercetin and rutin using glutathione metabolism on HO-induced oxidative stress in HepG2 cells. Annals of the New York Academy of Sciences, 1171, 530537. DOI: 10.1111/j.1749-6632.2009.04690.x

    Baghel, Satyendra & Shrivastava, Nikhil & Baghel, PA & Rajput, Sarlesh. (2012). A review of quercetin: Antioxidant and anticancer properties. World J Pharm Pharmaceutical Sci. 1. 146 - 160.

    Zinc

    Kaltenberg, J., Plum, L. M., Ober-Blöbaum, J. L., Hönscheid, A., Rink, L., & Haase, H. (2010). Zinc signals promote IL-2-dependent proliferation of T cells. European journal of immunology, 40(5), 14961503. DOI: 10.1002/eji.200939574

    Shankar, A. H., & Prasad, A. S. (1998). Zinc and immune function: the biological basis of altered resistance to infection. The American journal of clinical nutrition, 68(2 Suppl), 447S463S. DOI: 10.1093/ajcn/68.2.447S

    Barnett, J. B., Dao, M. C., Hamer, D. H., Kandel, R., Brandeis, G., Wu, D., Dallal, G. E., Jacques, P. F., Schreiber, R., Kong, E., & Meydani, S. N. (2016). Effect of zinc supplementation on serum zinc concentration and T cell proliferation in nursing home elderly: a randomized, double-blind, placebo-controlled trial. The American journal of clinical nutrition, 103(3), 942951. DOI: 10.3945/ajcn.115.115188

    Barnett JB, Hamer DH, Meydani SN. Low zinc status: a new risk factor for pneumonia in the elderly? Nutrition Reviews. 2010 Jan;68(1):30-37. DOI: 10.1111/j.1753-4887.2009.00253.x 

    Yasuda, Hiroshi. (2017). The Situation of Zinc Deficiency: Early Assessment and Intervention Are Essential. Biomedical Research on Trace Elements. 125-140. DOI: 10.11299/brte.27.125

    Hemilä H. Zinc lozenges may shorten the duration of colds: a systematic review. Open Respir Med J. 2011;5:5158. doi: 10.2174/1874306401105010051

    Rerksuppaphol, S., & Rerksuppaphol, L. (2013). A randomized controlled trial of chelated zinc for prevention of the common cold in Thai school children. Paediatrics and international child health, 33(3), 145150. DOI: 10.1179/2046905513Y.0000000064

    Supplement Facts

    Ingredients

    Suggested Use

    References

    Product Details

    • 1285 mg of vitamin C
    • 15 mg of zinc
    • Bioflavonoids: this daily vitamin c formula features citrus bioflavonoids, including grapefruit, lemon, and orange powders
    • Elderberry extract
    • Quercetin
    • Rose hips extract fruit
    • Vegan
    • Veggie capsules
    • Milk, wheat & soy-free
    • Paleo & keto friendly
    • Non-GMO and gluten-free
    • 2-month supply
    • Manufactured in the USA in a cGMP facility
    • Third-party tested

    Featured Ingredients

    Vitamin C Complex

    1285 mg

    Citrus Bioflavonoids

    Grapefruit, lemon and orange powders

    Elderberry Powder

    A source of vitamins

    Quercetin

    Flavonoid & plant pigment

    Zinc

    15 mg

    2 months supply

    Vegan and non-GMO Vitamin C capsule solution featuring citrus bioflavonoids, quercetin, rose hips, elderberry extracts, and zinc all-in-one.

    Suggested use

    Adults take 2 capsules daily with 8 ounces of water or your favorite beverage.  May be taken with or without food.

    See caution

    CAUTION: Do not exceed recommended dose. Please use caution if you have allergies or sensitivities to any of the listed ingredients. Pregnant or nursing mothers and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Use only as directed. If gastrointestinal discomfort (including bloating, cramps, diarrhea, or other digestive upset) or other sensitivity is experienced stop taking the product immediately. If you are pregnant, nursing, or have a medical condition, please consult with your physician before use. If you have any questions about consuming this dietary supplement, consult with your health care professional before using. If you use prescription drugs or over-the-counter medications, are unaware of your current medical condition or have a pre-existing medical condition(s), consult with your health care professional before using. Discontinue use immediately if you experience any adverse symptoms or reactions while taking this product. Discontinue use 2 weeks prior to surgery. Do not use if your health status is unknown. Do not use if safety seal is damaged or missing. Keep out of reach of children and pets. Store in a cool, dry place, away from heat moisture. Use this product as a food supplement only. Do not use for weight reduction.

    Additional Details

    2 months supply

    Vegan and non-GMO Vitamin C capsule solution featuring citrus bioflavonoids, quercetin, rose hips, elderberry extracts, and zinc all-in-one.

    See all ingredients

    Ingredients:

    Vitamin C (as Ascorbic Acid), Zinc (as Zinc Amino Acid Chelate), Citrus Bioflavonoid Complex: Grapefruit Powder (Fruit), Lemon Powder (Peel), Orange Powder (Fruit), Quercetin Dihydrate, Rose Hips Extract (Fruit), Elderberry Extract (Fruit; Std. to 5% Flavanoids). Other Ingredients: Methylcellulose Capsule.

    Pairs With

    References

    Vitamin C Complex

    Chambial S, Dwivedi S, Shukla KK, John PJ, Sharma P. Vitamin C in disease prevention and cure: an overview. Indian J Clin Biochem. 2013;28(4):314328.  doi: 10.1007/s12291-013-0375-3

    Traber MG, Stevens JF. Vitamins C and E: beneficial effects from a mechanistic perspective. Free Radic Biol Med. 2011;51(5):10001013. doi: 10.1016/j.freeradbiomed.2011.05.017

    See more

    Padayatty, S. J., Katz, A., Wang, Y., Eck, P., Kwon, O., Lee, J. H., Chen, S., Corpe, C., Dutta, A., Dutta, S. K., & Levine, M. (2003). Vitamin C as an antioxidant: evaluation of its role in disease prevention. Journal of the American College of Nutrition, 22(1), 1835. DOI: 10.1080/07315724.2003.10719272

    Pehlivan, Fadime. (2017). Vitamin C: An Antioxidant Agent. 10.5772/intechopen.69660. DOI: 10.5772/intechopen.69660

    A. Bendich, L.J. Machlin, O. Scandurra, G.W. Burton, D.D.M. Wayner, The antioxidant role of vitamin C, Advances in Free Radical Biology & Medicine, Volume 2, Issue 2, 1986, 419-444, 8755-9668. https://doi.org/10.1016/S8755-9668(86)80021-7

    Marc Bürzle, Matthias A. Hediger. Chapter Eleven: Functional and Physiological Role of Vitamin C Transporters. Mark O. Bevensee. Current Topics in Membranes. Academic Press. 70. 2012. 357-375. 1063-5823. 9780123943163. https://doi.org/10.1016/B978-0-12-394316-3.00011-9

    Akbari, Abolfazl & Jelodar, Gholamali & Nazifi, Saeed & Sajedianfard, Javad. (2016). An Overview of The characteristics and Function of Vitamin C in Various Tissues: Relying on its Antioxidant Function. Zahedan Journal of Research in Medical Sciences. In Press. DOI: 10.17795/zjrms-4037

    Chakraborthy, Aratirika & Ramani, Pratibha & Sherlin, Herald & Premkumar, Priya & Natesan, Anuja. (2014). Antioxidant and pro-oxidant activity of Vitamin C in oral environment. Indian journal of dental research : official publication of Indian Society for Dental Research. 25. 499-504. DOI: 10.4103/0970-9290.142547

    Sirmali, Rana & Giniş, Zeynep & Sirmali, Mehmet & Solak, Okan & Şeliman, Bengü & Ağaçkiran, Yetkin & Delibaş, Namık. (2014). Vitamin C as an antioxidant: evaluation of its role on pulmonary contusion experimental model. Turkish journal of medical sciences. 44. 905-13. DOI: 10.3906/sag-1309-139

    Citrus Bioflavonoids

    Stevens, Y., Rymenant, E. V., Grootaert, C., Camp, J. V., Possemiers, S., Masclee, A., & Jonkers, D. (2019). The Intestinal Fate of Citrus Flavanones and Their Effects on Gastrointestinal Health. Nutrients, 11(7), 1464. DOI: 10.3390/nu11071464

    Testai L, Calderone V. Nutraceutical Value of Citrus Flavanones and Their Implications in Cardiovascular Disease. Nutrients. 2017;9(5):502. Published 2017 May 16. doi: 10.3390/nu9050502

    Barreca, D., Gattuso, G., Bellocco, E., Calderaro, A., Trombetta, D., Smeriglio, A., Laganà, G., Daglia, M., Meneghini, S., & Nabavi, S. M. (2017). Flavanones: Citrus phytochemical with health-promoting properties. BioFactors (Oxford, England), 43(4), 495506. DOI: 10.1002/biof.1363

    Sharma, M., Akhtar, N., Sambhav, K., Shete, G., Bansal, A. K., & Sharma, S. S. (2015). Emerging potential of citrus flavanones as an antioxidant in diabetes and its complications. Current topics in medicinal chemistry, 15(2), 187195. DOI: 10.2174/1568026615666141209163013

    Chanet, A., Milenkovic, D., Manach, C., Mazur, A., & Morand, C. (2012). Citrus flavanones: what is their role in cardiovascular protection?. Journal of agricultural and food chemistry, 60(36), 88098822. DOI: 10.1021/jf300669s

    Zaidun, N. H., Thent, Z. C., & Latiff, A. A. (2018). Combating oxidative stress disorders with citrus flavonoid: Naringenin. Life sciences, 208, 111122. DOI: 10.1016/j.lfs.2018.07.017

    Assini, J. M., Mulvihill, E. E., & Huff, M. W. (2013). Citrus flavonoids and lipid metabolism. Current opinion in lipidology, 24(1), 3440. DOI: 10.1097/MOL.0b013e32835c07fd

    Asgary, S., Naderi, G., & Askari, N. (2005). Protective effect of flavonoids against red blood cell hemolysis by free radicals. Experimental and clinical cardiology, 10(2), 8890. PMCID: PMC2716227

    Elderberry Powder

    Sidor, Andrzej & Gramza Michalowska, Anna. (2014). Advanced research on the antioxidant and health benefit of elderberry (Sambucus nigra) in food a review. Journal of Functional Foods. 18. DOI: 10.1016/j.jff.2014.07.012

    Porter, R. S., & Bode, R. F. (2017). A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products. Phytotherapy research : PTR, 31(4), 533554. DOI: 10.1002/ptr.5782

    Zakay-Rones, Z., Thom, E., Wollan, T., & Wadstein, J. (2004). Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections. The Journal of international medical research, 32(2), 132140. DOI: 10.1177/147323000403200205

    Barak, V., Halperin, T., & Kalickman, I. (2001). The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. European cytokine network, 12(2), 290296. PMID: 11399518

    Hawkins, J., Baker, C., Cherry, L., & Dunne, E. (2019). Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials. Complementary therapies in medicine, 42, 361365. DOI: 10.1016/j.ctim.2018.12.004

    Tiralongo E, Wee SS, Lea RA. Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial. Nutrients. 2016;8(4):182. Published 2016 Mar 24. doi: 10.3390/nu8040182

    Porter, R. S., & Bode, R. F. (2017). A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products. Phytotherapy research : PTR, 31(4), 533554. DOI: 10.1002/ptr.5782

    Quercetin

    Selamoglu, Zeliha. (2016). Antioxidant Activity of Quercetin: A Mechanistic Review. Turkish Journal of Agriculture - Food Science and Technology. 4. 10.24925/turjaf.v4i12.1134-1138.1069. DOI: 10.24925/turjaf.v4i12.1134-1138.1069

    Anand David AV, Arulmoli R, Parasuraman S. Overviews of Biological Importance of Quercetin: A Bioactive Flavonoid. Pharmacogn Rev. 2016;10(20):8489. doi: 10.4103/0973-7847.194044

    Serban, M. C., Sahebkar, A., Zanchetti, A., Mikhailidis, D. P., Howard, G., Antal, D., Andrica, F., Ahmed, A., Aronow, W. S., Muntner, P., Lip, G. Y., Graham, I., Wong, N., Rysz, J., Banach, M., & Lipid and Blood Pressure Metaanalysis Collaboration (LBPMC) Group (2016). Effects of Quercetin on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Journal of the American Heart Association, 5(7), e002713. DOI: 10.1161/JAHA.115.002713

    Xu D, Hu MJ, Wang YQ, Cui YL. Antioxidant Activities of Quercetin and Its Complexes for Medicinal Application. Molecules. 2019;24(6):1123. Published 2019 Mar 21. doi: 10.3390/molecules24061123

    Alía, M., Mateos, R., Ramos, S., Lecumberri, E., Bravo, L., & Goya, L. (2006). Influence of quercetin and rutin on growth and antioxidant defense system of a human hepatoma cell line (HepG2). European journal of nutrition, 45(1), 1928. DOI: 10.1007/s00394-005-0558-7

    Robaszkiewicz, A., Balcerczyk, A., & Bartosz, G. (2007). Antioxidative and prooxidative effects of quercetin on A549 cells. Cell biology international, 31(10), 12451250. DOI: 10.1016/j.cellbi.2007.04.009

    Kim, G. N., & Jang, H. D. (2009). Protective mechanism of quercetin and rutin using glutathione metabolism on HO-induced oxidative stress in HepG2 cells. Annals of the New York Academy of Sciences, 1171, 530537. DOI: 10.1111/j.1749-6632.2009.04690.x

    Baghel, Satyendra & Shrivastava, Nikhil & Baghel, PA & Rajput, Sarlesh. (2012). A review of quercetin: Antioxidant and anticancer properties. World J Pharm Pharmaceutical Sci. 1. 146 - 160.

    Zinc

    Kaltenberg, J., Plum, L. M., Ober-Blöbaum, J. L., Hönscheid, A., Rink, L., & Haase, H. (2010). Zinc signals promote IL-2-dependent proliferation of T cells. European journal of immunology, 40(5), 14961503. DOI: 10.1002/eji.200939574

    Shankar, A. H., & Prasad, A. S. (1998). Zinc and immune function: the biological basis of altered resistance to infection. The American journal of clinical nutrition, 68(2 Suppl), 447S463S. DOI: 10.1093/ajcn/68.2.447S

    Barnett, J. B., Dao, M. C., Hamer, D. H., Kandel, R., Brandeis, G., Wu, D., Dallal, G. E., Jacques, P. F., Schreiber, R., Kong, E., & Meydani, S. N. (2016). Effect of zinc supplementation on serum zinc concentration and T cell proliferation in nursing home elderly: a randomized, double-blind, placebo-controlled trial. The American journal of clinical nutrition, 103(3), 942951. DOI: 10.3945/ajcn.115.115188

    Barnett JB, Hamer DH, Meydani SN. Low zinc status: a new risk factor for pneumonia in the elderly? Nutrition Reviews. 2010 Jan;68(1):30-37. DOI: 10.1111/j.1753-4887.2009.00253.x 

    Yasuda, Hiroshi. (2017). The Situation of Zinc Deficiency: Early Assessment and Intervention Are Essential. Biomedical Research on Trace Elements. 125-140. DOI: 10.11299/brte.27.125

    Hemilä H. Zinc lozenges may shorten the duration of colds: a systematic review. Open Respir Med J. 2011;5:5158. doi: 10.2174/1874306401105010051

    Rerksuppaphol, S., & Rerksuppaphol, L. (2013). A randomized controlled trial of chelated zinc for prevention of the common cold in Thai school children. Paediatrics and international child health, 33(3), 145150. DOI: 10.1179/2046905513Y.0000000064

    Vitamin C (as Ascorbic Acid), Zinc (as Zinc Amino Acid Chelate), Citrus Bioflavonoid Complex: Grapefruit Powder (Fruit), Lemon Powder (Peel), Orange Powder (Fruit), Quercetin Dihydrate, Rose Hips Extract (Fruit), Elderberry Extract (Fruit; Std. to 5% Flavanoids). Other Ingredients: Methylcellulose Capsule.

    Adults take 2 capsules daily with 8 ounces of water or your favorite beverage.  May be taken with or without food.

    CAUTION: Do not exceed recommended dose. Please use caution if you have allergies or sensitivities to any of the listed ingredients. Pregnant or nursing mothers and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Use only as directed. If gastrointestinal discomfort (including bloating, cramps, diarrhea, or other digestive upset) or other sensitivity is experienced stop taking the product immediately. If you are pregnant, nursing, or have a medical condition, please consult with your physician before use. If you have any questions about consuming this dietary supplement, consult with your health care professional before using. If you use prescription drugs or over-the-counter medications, are unaware of your current medical condition or have a pre-existing medical condition(s), consult with your health care professional before using. Discontinue use immediately if you experience any adverse symptoms or reactions while taking this product. Discontinue use 2 weeks prior to surgery. Do not use if your health status is unknown. Do not use if safety seal is damaged or missing. Keep out of reach of children and pets. Store in a cool, dry place, away from heat moisture. Use this product as a food supplement only. Do not use for weight reduction.

    Vitamin C Complex

    Chambial S, Dwivedi S, Shukla KK, John PJ, Sharma P. Vitamin C in disease prevention and cure: an overview. Indian J Clin Biochem. 2013;28(4):314328.  doi: 10.1007/s12291-013-0375-3

    Traber MG, Stevens JF. Vitamins C and E: beneficial effects from a mechanistic perspective. Free Radic Biol Med. 2011;51(5):10001013. doi: 10.1016/j.freeradbiomed.2011.05.017

    Padayatty, S. J., Katz, A., Wang, Y., Eck, P., Kwon, O., Lee, J. H., Chen, S., Corpe, C., Dutta, A., Dutta, S. K., & Levine, M. (2003). Vitamin C as an antioxidant: evaluation of its role in disease prevention. Journal of the American College of Nutrition, 22(1), 1835. DOI: 10.1080/07315724.2003.10719272

    Pehlivan, Fadime. (2017). Vitamin C: An Antioxidant Agent. 10.5772/intechopen.69660. DOI: 10.5772/intechopen.69660

    A. Bendich, L.J. Machlin, O. Scandurra, G.W. Burton, D.D.M. Wayner, The antioxidant role of vitamin C, Advances in Free Radical Biology & Medicine, Volume 2, Issue 2, 1986, 419-444, 8755-9668. https://doi.org/10.1016/S8755-9668(86)80021-7

    Marc Bürzle, Matthias A. Hediger. Chapter Eleven: Functional and Physiological Role of Vitamin C Transporters. Mark O. Bevensee. Current Topics in Membranes. Academic Press. 70. 2012. 357-375. 1063-5823. 9780123943163. https://doi.org/10.1016/B978-0-12-394316-3.00011-9

    Akbari, Abolfazl & Jelodar, Gholamali & Nazifi, Saeed & Sajedianfard, Javad. (2016). An Overview of The characteristics and Function of Vitamin C in Various Tissues: Relying on its Antioxidant Function. Zahedan Journal of Research in Medical Sciences. In Press. DOI: 10.17795/zjrms-4037

    Chakraborthy, Aratirika & Ramani, Pratibha & Sherlin, Herald & Premkumar, Priya & Natesan, Anuja. (2014). Antioxidant and pro-oxidant activity of Vitamin C in oral environment. Indian journal of dental research : official publication of Indian Society for Dental Research. 25. 499-504. DOI: 10.4103/0970-9290.142547

    Sirmali, Rana & Giniş, Zeynep & Sirmali, Mehmet & Solak, Okan & Şeliman, Bengü & Ağaçkiran, Yetkin & Delibaş, Namık. (2014). Vitamin C as an antioxidant: evaluation of its role on pulmonary contusion experimental model. Turkish journal of medical sciences. 44. 905-13. DOI: 10.3906/sag-1309-139

    Citrus Bioflavonoids

    Stevens, Y., Rymenant, E. V., Grootaert, C., Camp, J. V., Possemiers, S., Masclee, A., & Jonkers, D. (2019). The Intestinal Fate of Citrus Flavanones and Their Effects on Gastrointestinal Health. Nutrients, 11(7), 1464. DOI: 10.3390/nu11071464

    Testai L, Calderone V. Nutraceutical Value of Citrus Flavanones and Their Implications in Cardiovascular Disease. Nutrients. 2017;9(5):502. Published 2017 May 16. doi: 10.3390/nu9050502

    Barreca, D., Gattuso, G., Bellocco, E., Calderaro, A., Trombetta, D., Smeriglio, A., Laganà, G., Daglia, M., Meneghini, S., & Nabavi, S. M. (2017). Flavanones: Citrus phytochemical with health-promoting properties. BioFactors (Oxford, England), 43(4), 495506. DOI: 10.1002/biof.1363

    Sharma, M., Akhtar, N., Sambhav, K., Shete, G., Bansal, A. K., & Sharma, S. S. (2015). Emerging potential of citrus flavanones as an antioxidant in diabetes and its complications. Current topics in medicinal chemistry, 15(2), 187195. DOI: 10.2174/1568026615666141209163013

    Chanet, A., Milenkovic, D., Manach, C., Mazur, A., & Morand, C. (2012). Citrus flavanones: what is their role in cardiovascular protection?. Journal of agricultural and food chemistry, 60(36), 88098822. DOI: 10.1021/jf300669s

    Zaidun, N. H., Thent, Z. C., & Latiff, A. A. (2018). Combating oxidative stress disorders with citrus flavonoid: Naringenin. Life sciences, 208, 111122. DOI: 10.1016/j.lfs.2018.07.017

    Assini, J. M., Mulvihill, E. E., & Huff, M. W. (2013). Citrus flavonoids and lipid metabolism. Current opinion in lipidology, 24(1), 3440. DOI: 10.1097/MOL.0b013e32835c07fd

    Asgary, S., Naderi, G., & Askari, N. (2005). Protective effect of flavonoids against red blood cell hemolysis by free radicals. Experimental and clinical cardiology, 10(2), 8890. PMCID: PMC2716227

    Elderberry Powder

    Sidor, Andrzej & Gramza Michalowska, Anna. (2014). Advanced research on the antioxidant and health benefit of elderberry (Sambucus nigra) in food a review. Journal of Functional Foods. 18. DOI: 10.1016/j.jff.2014.07.012

    Porter, R. S., & Bode, R. F. (2017). A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products. Phytotherapy research : PTR, 31(4), 533554. DOI: 10.1002/ptr.5782

    Zakay-Rones, Z., Thom, E., Wollan, T., & Wadstein, J. (2004). Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections. The Journal of international medical research, 32(2), 132140. DOI: 10.1177/147323000403200205

    Barak, V., Halperin, T., & Kalickman, I. (2001). The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. European cytokine network, 12(2), 290296. PMID: 11399518

    Hawkins, J., Baker, C., Cherry, L., & Dunne, E. (2019). Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials. Complementary therapies in medicine, 42, 361365. DOI: 10.1016/j.ctim.2018.12.004

    Tiralongo E, Wee SS, Lea RA. Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial. Nutrients. 2016;8(4):182. Published 2016 Mar 24. doi: 10.3390/nu8040182

    Porter, R. S., & Bode, R. F. (2017). A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products. Phytotherapy research : PTR, 31(4), 533554. DOI: 10.1002/ptr.5782

    Quercetin

    Selamoglu, Zeliha. (2016). Antioxidant Activity of Quercetin: A Mechanistic Review. Turkish Journal of Agriculture - Food Science and Technology. 4. 10.24925/turjaf.v4i12.1134-1138.1069. DOI: 10.24925/turjaf.v4i12.1134-1138.1069

    Anand David AV, Arulmoli R, Parasuraman S. Overviews of Biological Importance of Quercetin: A Bioactive Flavonoid. Pharmacogn Rev. 2016;10(20):8489. doi: 10.4103/0973-7847.194044

    Serban, M. C., Sahebkar, A., Zanchetti, A., Mikhailidis, D. P., Howard, G., Antal, D., Andrica, F., Ahmed, A., Aronow, W. S., Muntner, P., Lip, G. Y., Graham, I., Wong, N., Rysz, J., Banach, M., & Lipid and Blood Pressure Metaanalysis Collaboration (LBPMC) Group (2016). Effects of Quercetin on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Journal of the American Heart Association, 5(7), e002713. DOI: 10.1161/JAHA.115.002713

    Xu D, Hu MJ, Wang YQ, Cui YL. Antioxidant Activities of Quercetin and Its Complexes for Medicinal Application. Molecules. 2019;24(6):1123. Published 2019 Mar 21. doi: 10.3390/molecules24061123

    Alía, M., Mateos, R., Ramos, S., Lecumberri, E., Bravo, L., & Goya, L. (2006). Influence of quercetin and rutin on growth and antioxidant defense system of a human hepatoma cell line (HepG2). European journal of nutrition, 45(1), 1928. DOI: 10.1007/s00394-005-0558-7

    Robaszkiewicz, A., Balcerczyk, A., & Bartosz, G. (2007). Antioxidative and prooxidative effects of quercetin on A549 cells. Cell biology international, 31(10), 12451250. DOI: 10.1016/j.cellbi.2007.04.009

    Kim, G. N., & Jang, H. D. (2009). Protective mechanism of quercetin and rutin using glutathione metabolism on HO-induced oxidative stress in HepG2 cells. Annals of the New York Academy of Sciences, 1171, 530537. DOI: 10.1111/j.1749-6632.2009.04690.x

    Baghel, Satyendra & Shrivastava, Nikhil & Baghel, PA & Rajput, Sarlesh. (2012). A review of quercetin: Antioxidant and anticancer properties. World J Pharm Pharmaceutical Sci. 1. 146 - 160.

    Zinc

    Kaltenberg, J., Plum, L. M., Ober-Blöbaum, J. L., Hönscheid, A., Rink, L., & Haase, H. (2010). Zinc signals promote IL-2-dependent proliferation of T cells. European journal of immunology, 40(5), 14961503. DOI: 10.1002/eji.200939574

    Shankar, A. H., & Prasad, A. S. (1998). Zinc and immune function: the biological basis of altered resistance to infection. The American journal of clinical nutrition, 68(2 Suppl), 447S463S. DOI: 10.1093/ajcn/68.2.447S

    Barnett, J. B., Dao, M. C., Hamer, D. H., Kandel, R., Brandeis, G., Wu, D., Dallal, G. E., Jacques, P. F., Schreiber, R., Kong, E., & Meydani, S. N. (2016). Effect of zinc supplementation on serum zinc concentration and T cell proliferation in nursing home elderly: a randomized, double-blind, placebo-controlled trial. The American journal of clinical nutrition, 103(3), 942951. DOI: 10.3945/ajcn.115.115188

    Barnett JB, Hamer DH, Meydani SN. Low zinc status: a new risk factor for pneumonia in the elderly? Nutrition Reviews. 2010 Jan;68(1):30-37. DOI: 10.1111/j.1753-4887.2009.00253.x 

    Yasuda, Hiroshi. (2017). The Situation of Zinc Deficiency: Early Assessment and Intervention Are Essential. Biomedical Research on Trace Elements. 125-140. DOI: 10.11299/brte.27.125

    Hemilä H. Zinc lozenges may shorten the duration of colds: a systematic review. Open Respir Med J. 2011;5:5158. doi: 10.2174/1874306401105010051

    Rerksuppaphol, S., & Rerksuppaphol, L. (2013). A randomized controlled trial of chelated zinc for prevention of the common cold in Thai school children. Paediatrics and international child health, 33(3), 145150. DOI: 10.1179/2046905513Y.0000000064

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    Customer Reviews
    4.9 Based on 16 Reviews
    5 ★
    94% 
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    Your input is very much appreciated. Share it with your friends so they can enjoy it too!

    Filter Reviews:
    • Vitamin C
    • Zinc
    • Quercetin
    • immune system
    • pill
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    A
    11/07/2022
    Alex
    United States United States

    Good vitamin C

    Good vitamin C, I like that includes other good vitamins the immune system too. It is easy to take and no side effects.

    M
    11/03/2022
    Maria
    United States United States

    Excellent product

    Easy to swallow, no bitter after taste or upset stomach. Love that along with vitamin C there are additional supplements.

    JA
    10/31/2022
    Jacqueline A.
    United States United States

    Love it!

    My husband and I recently got very sick with a cold and I heard of this vitamins before so I bought it and immediately we started feeling better within the days ! So do not hesitate in buying this for you and your family during this cold days to come !

    MB
    10/29/2022
    Maria B.
    United States United States

    Easy to swallow and digest

    These were easy to take without bitter aftertaste and did not upset or make my stomach queasy. Excited to be able to take a vitamin C with no after effects throughout the day.

    DH
    10/26/2022
    Denise H.
    United States United States

    Great Immune Support

    Great product all in one for immune support!

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