Zoom Amen Leaky Gut Health Capsules Supplement  With Botanicals, Herbs & Zinc
Zoom Amen Leaky Gut Health Formula Botanicals and Probiotics Capsules Supplement

Amen Leaky Gut+

For Gut & Digestion Support*
    $22.99
    81 reviews
    Bestseller

    Description

    Product Details

    • L-glutamine
    • Zinc
    • Fermented organic botanical blend
    • Organic apple cider vinegar
    • Organic ginger root
    • Organic turmeric root
    • Organic marshmallow root powder
    • Probiotic blend (10 billion CFUs)*
    • Deglycyrrhizinated licorice extract - DGL
    • Veggie capsules
    • Fermented
    • Vegan & non-GMO
    • Dairy, soy, and gluten-free
    • Paleo and keto-friendly
    • 1 month supply
    • Third-party tested
    • Manufactured in the USA in a cGMP-certified facility
    • L-glutamine and glutamine are frequently used interchangeably. The enzyme glutamine synthetase (GS) is primarily responsible for producing glutamine, which is then hydrolyzed by the enzyme glutaminase (GLS)

    Featured Ingredients

    Zinc

    15 mg

    Organic Apple Cider Vinegar

    Acetic acid

    Organic Turmeric Root

    From the ginger family

    Deglycyrrhizinated Licorice Extract

    Licorice contains flavonoids & phytoestrogens

    L-Glutamine

    An important amino acid

    The right gut feeling

    Our gut deserves a unique care. It’s an important building block to a healthy you. Amen Leaky Gut provides a combination of prebiotics, probiotics, zinc, and L-glutamine.

    Suggested use

    Take 3 capsules daily with 8 ounces of water or your favorite beverage. May be taken with or without food.

    See caution

    CAUTION: Do not exceed recommended dose. If you are allergic, or think you may be allergic to any of the listed ingredients, consult your primary healthcare physician before consuming. If you are pregnant, nursing, have a medical condition, or taking any medication, consult your doctor before using this product. If you experience an allergic reaction, please stop using the product immediately and contact your doctor. Do no exceed recommended dose. If your item appears to be damaged upon arrival, please contact us immediately. Additionally, if you experience any adverse reactions such as stomach pains, nausea, diarrhea, headache, rash, or others, please stop taking this product immediately and contact your doctor. Color and odor may vary from batch to batch. Contains no filler ingredients, artificial flavors, colors, sweeteners, or preservatives. Keep out of reach of children and pets. Use this product as a food supplement only. Do not use for weight reduction.

    Additional Details

    The right gut feeling

    Our gut deserves a unique care. It’s an important building block to a healthy you. Amen Leaky Gut provides a combination of prebiotics, probiotics, zinc, and L-glutamine.

    See all ingredients

    Ingredients:

    Fermented Organic Botanical Blend: Organic Apple Cider Vinegar, Organic Ginger Root (Zingiber officinale), Organic Turmeric Root (Curcuma longa), Deglycyrrhizinated Licorice Extract, L-Glutamine, Organic Marshmallow Root Powder, Probiotic Blend (1OB CFU†): B. clausil, B. coagulans, B. subtilis, S. boularadii. Other Ingredients: Methylcellulose Capsule.

    †At time of manufacture.

    Pairs With

    References

    Zinc

    Maggini S, Pierre A, Calder PC. Immune Function and Micronutrient Requirements Change over the Life Course. Nutrients. 2018;10(10):1531. Published 2018 Oct 17. doi: 10.3390/nu10101531

    Gombart AF, Pierre A, Maggini S. A Review of Micronutrients and the Immune System-Working in Harmony to Reduce the Risk of Infection. Nutrients. 2020;12(1):236. Published 2020 Jan 16. doi: 10.3390/nu12010236

    See more

    Prasad AS. Zinc in human health: effect of zinc on immune cells. Mol Med. 2008;14(5-6):353357. doi: 10.2119/2008-00033.Prasad

    Melissa L. Zastrow and Vincent L. Pecoraro. Designing Hydrolytic Zinc Metalloenzymes. Biochemistry 2014 53 (6), 957-978. February 7, 2014. DOI: 10.1021/bi4016617

    Technical University of Munich (TUM). "Diet lacking in zinc is detrimental to human, animal health: Even moderate zinc deficiency is bad for digestion." ScienceDaily. ScienceDaily, 9 June 2016.

    Organic Apple Cider Vinegar

    Johnston, C. S., & Gaas, C. A. (2006). Vinegar: medicinal uses and antiglycemic effect. MedGenMed : Medscape general medicine, 8(2), 61. PMID: 16926800

    Beh, B. K., Mohamad, N. E., Yeap, S. K., Ky, H., Boo, S. Y., Chua, J., Tan, S. W., Ho, W. Y., Sharifuddin, S. A., Long, K., & Alitheen, N. B. (2017). Anti-obesity and anti-inflammatory effects of synthetic acetic acid vinegar and Nipa vinegar on high-fat-diet-induced obese mice. Scientific reports, 7(1), 6664. doi: 10.1038/s41598-017-06235-7

    Santos, H. O., de Moraes, W., da Silva, G., Prestes, J., & Schoenfeld, B. J. (2019). Vinegar (acetic acid) intake on glucose metabolism: A narrative review. Clinical nutrition ESPEN, 32, 17. DOI: 10.1016/j.clnesp.2019.05.008

    Ostman, E., Granfeldt, Y., Persson, L., & Björck, I. (2005). Vinegar supplementation lowers glucose and insulin responses and increases satiety after a bread meal in healthy subjects. European journal of clinical nutrition, 59(9), 983988. DOI: 10.1038/sj.ejcn.1602197

    Shishehbor, F., Mansoori, A., & Shirani, F. (2017). Vinegar consumption can attenuate postprandial glucose and insulin responses; a systematic review and meta-analysis of clinical trials. Diabetes research and clinical practice, 127, 19. https://doi.org/10.1016/j.diabres.2017.01.021 DOI: 10.1016/j.diabres.2017.01.021

    Lim, J., Henry, C. J., & Haldar, S. (2016). Vinegar as a functional ingredient to improve postprandial glycemic control-human intervention findings and molecular mechanisms. Molecular nutrition & food research, 60(8), 18371849. DOI: 10.1002/mnfr.201600121

    Organic Turmeric Root

    Hewlings SJ, Kalman DS. Curcumin: A Review of Its' Effects on Human Health. Foods. 2017;6(10):92. Published 2017 Oct 22. doi.org/10.3390/foods6100092.

    Langhans, Sigrid. (2011). Therapeutic potential of curcumin in gastrointestinal diseases. World journal of gastrointestinal pathophysiology. 2. 1-14. DOI: 10.4291/wjgp.v2.i1.1

    Adrian L Lopresti, The Problem of Curcumin and Its Bioavailability: Could Its Gastrointestinal Influence Contribute to Its Overall Health-Enhancing Effects?, Advances in Nutrition, Volume 9, Issue 1, January 2018, Pages 4150, https://doi.org/10.1093/advances/nmx011

    Chainani-Wu N. (2003). Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa). Journal of alternative and complementary medicine (New York, N.Y.), 9(1), 161168. DOI: 10.1089/107555303321223035

    Zdrojewicz, Z., Szyca, M., Popowicz, E., Michalik, T., & Śmieszniak, B. (2017). Kurkuma nie tylko przyprawa [Turmeric - not only spice]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 42(252), 227230. PMID: 28662006

    Gupta, S. C., Sung, B., Kim, J. H., Prasad, S., Li, S., & Aggarwal, B. B. (2013). Multitargeting by turmeric, the golden spice: From kitchen to clinic. Molecular nutrition & food research, 57(9), 15101528. DOI: 10.1002/mnfr.201100741

    Deglycyrrhizinated Licorice Extract

    Hsu, Y. C., Chang, P. J., Tung, C. W., Shih, Y. H., Ni, W. C., Li, Y. C., Uto, T., Shoyama, Y., Ho, C., & Lin, C. L. (2020). De-Glycyrrhizinated Licorice Extract Attenuates High Glucose-Stimulated Renal Tubular Epithelial-Mesenchymal Transition via Suppressing the Notch2 Signaling Pathway. Cells, 9(1), 125. doi: 10.3390/cells9010125

    Messier, C., Epifano, F., Genovese, S., & Grenier, D. (2012). Licorice and its potential beneficial effects in common oro-dental diseases. Oral diseases, 18(1), 3239. DOI: 10.1111/j.1601-0825.2011.01842.x

    Dhiman, R. K., & Chawla, Y. K. (2005). Herbal medicines for liver diseases. Digestive diseases and sciences, 50(10), 18071812. DOI: 10.1007/s10620-005-2942-9

    Sun, Z. G., Zhao, T. T., Lu, N., Yang, Y. A., & Zhu, H. L. (2019). Research Progress of Glycyrrhizic Acid on Antiviral Activity. Mini reviews in medicinal chemistry, 19(10), 826832. DOI: 10.2174/1389557519666190119111125

    Raveendra, K. R., Jayachandra, Srinivasa, V., Sushma, K. R., Allan, J. J., Goudar, K. S., Shivaprasad, H. N., Venkateshwarlu, K., Geetharani, P., Sushma, G., & Agarwal, A. (2012). An Extract of Glycyrrhiza glabra (GutGard) Alleviates Symptoms of Functional Dyspepsia: A Randomized, Double-Blind, Placebo-Controlled Study. Evidence-based complementary and alternative medicine : eCAM, 2012, 216970. doi: 10.1155/2012/216970

    L-Glutamine

    Weschawalit S, Thongthip S, Phutrakool P, Asawanonda P. Glutathione and its antiaging and antimelanogenic effects. Clin Cosmet Investig Dermatol. 2017;10:147153. Published 2017 Apr 27. doi: 10.2147/CCID.S128339

    Gaucher C, Boudier A, Bonetti J, Clarot I, Leroy P, Parent M. Glutathione: Antioxidant Properties Dedicated to Nanotechnologies. Antioxidants (Basel). 2018;7(5):62. Published 2018 Apr 27. doi: 10.3390/antiox7050062

    Honda, Y., Kessoku, T., Sumida, Y., Kobayashi, T., Kato, T., Ogawa, Y., Tomeno, W., Imajo, K., Fujita, K., Yoneda, M., Kataoka, K., Taguri, M., Yamanaka, T., Seko, Y., Tanaka, S., Saito, S., Ono, M., Oeda, S., Eguchi, Y., Aoi, W., Nakajima, A. (2017). Efficacy of glutathione for the treatment of nonalcoholic fatty liver disease: an open-label, single-arm, multicenter, pilot study. BMC gastroenterology, 17(1), 96. DOI: 10.1186/s12876-017-0652-3

    Perricone, C., De Carolis, C., & Perricone, R. (2009). Glutathione: a key player in autoimmunity. Autoimmunity reviews, 8(8), 697701. DOI: 10.1016/j.autrev.2009.02.020

    Rose, S., Melnyk, S., Pavliv, O., Bai, S., Nick, T. G., Frye, R. E., & James, S. J. (2012). Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain. Translational psychiatry, 2(7), e134. DOI: 10.1038/tp.2012.61

    Kerksick C, Willoughby D. The antioxidant role of glutathione and N-acetyl-cysteine supplements and exercise-induced oxidative stress. J Int Soc Sports Nutr. 2005;2(2):3844. Published 2005 Dec 9. doi: 10.1186/1550-2783-2-2-38Hakki Kalkan I, Suher M. The relationship between the level of glutathione, impairment of glucose metabolism and complications of diabetes mellitus. Pak J Med Sci. 2013;29(4):938942. doi: 10.12669/pjms.294.2859

    Tessier F, Margaritis I, Richard MJ, Moynot C, Marconnet P. Selenium and training effects on the glutathione system and aerobic performance. Medicine and Science in Sports and Exercise. 1995 Mar;27(3):390-396. PMID: 7752866

    Sacco, R., Eggenhoffner, R., & Giacomelli, L. (2016). Glutathione in the treatment of liver diseases: insights from clinical practice. Minerva gastroenterologica e dietologica, 62(4), 316324. PMID: 27603810

    Gibson SA, Korade Ž, Shelton RC. Oxidative stress and glutathione response in tissue cultures from persons with major depression. J Psychiatr Res. 2012;46(10):13261332. doi: 10.1016/j.jpsychires.2012.06.008

    Lapidus, K. A., Gabbay, V., Mao, X., Johnson, A., Murrough, J. W., Mathew, S. J., & Shungu, D. C. (2014). In vivo (1)H MRS study of potential associations between glutathione, oxidative stress and anhedonia in major depressive disorder. Neuroscience letters, 569, 7479. DOI: 10.1016/j.neulet.2014.03.056

    Adeoye O, Olawumi J, Opeyemi A, Christiania O. Review on the role of glutathione on oxidative stress and infertility. JBRA Assisted Reproduction. 2018 Mar;22(1):61-66. DOI: 10.5935/1518-0557.20180003

    Grucza, K., Chołbiński, P., Kwiatkowska, D., Szutowski, M.M., & Techasen, A. (2019). Effects of Supplementation with Glutathione and its Precursors on Athlete Performance. Biomedical Journal of Scientific and Technical Research, 12, 001-008. DOI: 10.26717/BJSTR.2019.12.002293

    Aoi W, Ogaya Y, Takami M, et al. Glutathione supplementation suppresses muscle fatigue induced by prolonged exercise via improved aerobic metabolism. J Int Soc Sports Nutr. 2015;12:7. Published 2015 Feb 6. doi: 10.1186/s12970-015-0067-x

    Buonocore D, Grosini M, Giardina S, et al. Bioavailability Study of an Innovative Orobuccal Formulation of Glutathione. Oxid Med Cell Longev. 2016;2016:3286365. doi: 10.1155/2016/3286365

    Chiang GC, Mao X, Kang G, et al. Relationships among Cortical Glutathione Levels, Brain Amyloidosis, and Memory in Healthy Older Adults Investigated In Vivo with 1H-MRS and Pittsburgh Compound-B PET. AJNR Am J Neuroradiol. 2017;38(6):11301137. doi: 10.3174/ajnr.A5143

    Dringen, R., & Hirrlinger, J. (2003). Glutathione pathways in the brain. Biological chemistry, 384(4), 505516. DOI: 10.1515/BC.2003.059

    Dwivedi, D., Megha, K., Mishra, R., & Mandal, P. K. (2020). Glutathione in Brain: Overview of Its Conformations, Functions, Biochemical Characteristics, Quantitation and Potential Therapeutic Role in Brain Disorders. Neurochemical research, 10.1007/s11064-020-03030-1. Advance online publication. DOI: 10.1007/s11064-020-03030-1

    Tong, J., Fitzmaurice, P. S., Moszczynska, A., Mattina, K., Ang, L. C., Boileau, I., Furukawa, Y., Sailasuta, N., & Kish, S. J. (2016). Do glutathione levels decline in aging human brain?. Free radical biology & medicine, 93, 110117. DOI: 10.1016/j.freeradbiomed.2016.01.029

    Sekhar R, Kumar P, Liu C. REVERSING AGING: PREVENTING AGE-RELATED DECLINE IN GLUTATHIONE AND MITOCHONDRIAL FUNCTION INCREASES LONGEVITY. Innov Aging. 2018;2(Suppl 1):887. Published 2018 Nov 16. doi: 10.1093/geroni/igy031.3309

    Supplement Facts

    Ingredients

    Suggested Use

    References

    Product Details

    • L-glutamine
    • Zinc
    • Fermented organic botanical blend
    • Organic apple cider vinegar
    • Organic ginger root
    • Organic turmeric root
    • Organic marshmallow root powder
    • Probiotic blend (10 billion CFUs)*
    • Deglycyrrhizinated licorice extract - DGL
    • Veggie capsules
    • Fermented
    • Vegan & non-GMO
    • Dairy, soy, and gluten-free
    • Paleo and keto-friendly
    • 1 month supply
    • Third-party tested
    • Manufactured in the USA in a cGMP-certified facility
    • L-glutamine and glutamine are frequently used interchangeably. The enzyme glutamine synthetase (GS) is primarily responsible for producing glutamine, which is then hydrolyzed by the enzyme glutaminase (GLS)

    Featured Ingredients

    Zinc

    15 mg

    Organic Apple Cider Vinegar

    Acetic acid

    Organic Turmeric Root

    From the ginger family

    Deglycyrrhizinated Licorice Extract

    Licorice contains flavonoids & phytoestrogens

    L-Glutamine

    An important amino acid

    The right gut feeling

    Our gut deserves a unique care. It’s an important building block to a healthy you. Amen Leaky Gut provides a combination of prebiotics, probiotics, zinc, and L-glutamine.

    Suggested use

    Take 3 capsules daily with 8 ounces of water or your favorite beverage. May be taken with or without food.

    See caution

    CAUTION: Do not exceed recommended dose. If you are allergic, or think you may be allergic to any of the listed ingredients, consult your primary healthcare physician before consuming. If you are pregnant, nursing, have a medical condition, or taking any medication, consult your doctor before using this product. If you experience an allergic reaction, please stop using the product immediately and contact your doctor. Do no exceed recommended dose. If your item appears to be damaged upon arrival, please contact us immediately. Additionally, if you experience any adverse reactions such as stomach pains, nausea, diarrhea, headache, rash, or others, please stop taking this product immediately and contact your doctor. Color and odor may vary from batch to batch. Contains no filler ingredients, artificial flavors, colors, sweeteners, or preservatives. Keep out of reach of children and pets. Use this product as a food supplement only. Do not use for weight reduction.

    Additional Details

    The right gut feeling

    Our gut deserves a unique care. It’s an important building block to a healthy you. Amen Leaky Gut provides a combination of prebiotics, probiotics, zinc, and L-glutamine.

    See all ingredients

    Ingredients:

    Fermented Organic Botanical Blend: Organic Apple Cider Vinegar, Organic Ginger Root (Zingiber officinale), Organic Turmeric Root (Curcuma longa), Deglycyrrhizinated Licorice Extract, L-Glutamine, Organic Marshmallow Root Powder, Probiotic Blend (1OB CFU†): B. clausil, B. coagulans, B. subtilis, S. boularadii. Other Ingredients: Methylcellulose Capsule.

    †At time of manufacture.

    Pairs With

    References

    Zinc

    Maggini S, Pierre A, Calder PC. Immune Function and Micronutrient Requirements Change over the Life Course. Nutrients. 2018;10(10):1531. Published 2018 Oct 17. doi: 10.3390/nu10101531

    Gombart AF, Pierre A, Maggini S. A Review of Micronutrients and the Immune System-Working in Harmony to Reduce the Risk of Infection. Nutrients. 2020;12(1):236. Published 2020 Jan 16. doi: 10.3390/nu12010236

    See more

    Prasad AS. Zinc in human health: effect of zinc on immune cells. Mol Med. 2008;14(5-6):353357. doi: 10.2119/2008-00033.Prasad

    Melissa L. Zastrow and Vincent L. Pecoraro. Designing Hydrolytic Zinc Metalloenzymes. Biochemistry 2014 53 (6), 957-978. February 7, 2014. DOI: 10.1021/bi4016617

    Technical University of Munich (TUM). "Diet lacking in zinc is detrimental to human, animal health: Even moderate zinc deficiency is bad for digestion." ScienceDaily. ScienceDaily, 9 June 2016.

    Organic Apple Cider Vinegar

    Johnston, C. S., & Gaas, C. A. (2006). Vinegar: medicinal uses and antiglycemic effect. MedGenMed : Medscape general medicine, 8(2), 61. PMID: 16926800

    Beh, B. K., Mohamad, N. E., Yeap, S. K., Ky, H., Boo, S. Y., Chua, J., Tan, S. W., Ho, W. Y., Sharifuddin, S. A., Long, K., & Alitheen, N. B. (2017). Anti-obesity and anti-inflammatory effects of synthetic acetic acid vinegar and Nipa vinegar on high-fat-diet-induced obese mice. Scientific reports, 7(1), 6664. doi: 10.1038/s41598-017-06235-7

    Santos, H. O., de Moraes, W., da Silva, G., Prestes, J., & Schoenfeld, B. J. (2019). Vinegar (acetic acid) intake on glucose metabolism: A narrative review. Clinical nutrition ESPEN, 32, 17. DOI: 10.1016/j.clnesp.2019.05.008

    Ostman, E., Granfeldt, Y., Persson, L., & Björck, I. (2005). Vinegar supplementation lowers glucose and insulin responses and increases satiety after a bread meal in healthy subjects. European journal of clinical nutrition, 59(9), 983988. DOI: 10.1038/sj.ejcn.1602197

    Shishehbor, F., Mansoori, A., & Shirani, F. (2017). Vinegar consumption can attenuate postprandial glucose and insulin responses; a systematic review and meta-analysis of clinical trials. Diabetes research and clinical practice, 127, 19. https://doi.org/10.1016/j.diabres.2017.01.021 DOI: 10.1016/j.diabres.2017.01.021

    Lim, J., Henry, C. J., & Haldar, S. (2016). Vinegar as a functional ingredient to improve postprandial glycemic control-human intervention findings and molecular mechanisms. Molecular nutrition & food research, 60(8), 18371849. DOI: 10.1002/mnfr.201600121

    Organic Turmeric Root

    Hewlings SJ, Kalman DS. Curcumin: A Review of Its' Effects on Human Health. Foods. 2017;6(10):92. Published 2017 Oct 22. doi.org/10.3390/foods6100092.

    Langhans, Sigrid. (2011). Therapeutic potential of curcumin in gastrointestinal diseases. World journal of gastrointestinal pathophysiology. 2. 1-14. DOI: 10.4291/wjgp.v2.i1.1

    Adrian L Lopresti, The Problem of Curcumin and Its Bioavailability: Could Its Gastrointestinal Influence Contribute to Its Overall Health-Enhancing Effects?, Advances in Nutrition, Volume 9, Issue 1, January 2018, Pages 4150, https://doi.org/10.1093/advances/nmx011

    Chainani-Wu N. (2003). Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa). Journal of alternative and complementary medicine (New York, N.Y.), 9(1), 161168. DOI: 10.1089/107555303321223035

    Zdrojewicz, Z., Szyca, M., Popowicz, E., Michalik, T., & Śmieszniak, B. (2017). Kurkuma nie tylko przyprawa [Turmeric - not only spice]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 42(252), 227230. PMID: 28662006

    Gupta, S. C., Sung, B., Kim, J. H., Prasad, S., Li, S., & Aggarwal, B. B. (2013). Multitargeting by turmeric, the golden spice: From kitchen to clinic. Molecular nutrition & food research, 57(9), 15101528. DOI: 10.1002/mnfr.201100741

    Deglycyrrhizinated Licorice Extract

    Hsu, Y. C., Chang, P. J., Tung, C. W., Shih, Y. H., Ni, W. C., Li, Y. C., Uto, T., Shoyama, Y., Ho, C., & Lin, C. L. (2020). De-Glycyrrhizinated Licorice Extract Attenuates High Glucose-Stimulated Renal Tubular Epithelial-Mesenchymal Transition via Suppressing the Notch2 Signaling Pathway. Cells, 9(1), 125. doi: 10.3390/cells9010125

    Messier, C., Epifano, F., Genovese, S., & Grenier, D. (2012). Licorice and its potential beneficial effects in common oro-dental diseases. Oral diseases, 18(1), 3239. DOI: 10.1111/j.1601-0825.2011.01842.x

    Dhiman, R. K., & Chawla, Y. K. (2005). Herbal medicines for liver diseases. Digestive diseases and sciences, 50(10), 18071812. DOI: 10.1007/s10620-005-2942-9

    Sun, Z. G., Zhao, T. T., Lu, N., Yang, Y. A., & Zhu, H. L. (2019). Research Progress of Glycyrrhizic Acid on Antiviral Activity. Mini reviews in medicinal chemistry, 19(10), 826832. DOI: 10.2174/1389557519666190119111125

    Raveendra, K. R., Jayachandra, Srinivasa, V., Sushma, K. R., Allan, J. J., Goudar, K. S., Shivaprasad, H. N., Venkateshwarlu, K., Geetharani, P., Sushma, G., & Agarwal, A. (2012). An Extract of Glycyrrhiza glabra (GutGard) Alleviates Symptoms of Functional Dyspepsia: A Randomized, Double-Blind, Placebo-Controlled Study. Evidence-based complementary and alternative medicine : eCAM, 2012, 216970. doi: 10.1155/2012/216970

    L-Glutamine

    Weschawalit S, Thongthip S, Phutrakool P, Asawanonda P. Glutathione and its antiaging and antimelanogenic effects. Clin Cosmet Investig Dermatol. 2017;10:147153. Published 2017 Apr 27. doi: 10.2147/CCID.S128339

    Gaucher C, Boudier A, Bonetti J, Clarot I, Leroy P, Parent M. Glutathione: Antioxidant Properties Dedicated to Nanotechnologies. Antioxidants (Basel). 2018;7(5):62. Published 2018 Apr 27. doi: 10.3390/antiox7050062

    Honda, Y., Kessoku, T., Sumida, Y., Kobayashi, T., Kato, T., Ogawa, Y., Tomeno, W., Imajo, K., Fujita, K., Yoneda, M., Kataoka, K., Taguri, M., Yamanaka, T., Seko, Y., Tanaka, S., Saito, S., Ono, M., Oeda, S., Eguchi, Y., Aoi, W., Nakajima, A. (2017). Efficacy of glutathione for the treatment of nonalcoholic fatty liver disease: an open-label, single-arm, multicenter, pilot study. BMC gastroenterology, 17(1), 96. DOI: 10.1186/s12876-017-0652-3

    Perricone, C., De Carolis, C., & Perricone, R. (2009). Glutathione: a key player in autoimmunity. Autoimmunity reviews, 8(8), 697701. DOI: 10.1016/j.autrev.2009.02.020

    Rose, S., Melnyk, S., Pavliv, O., Bai, S., Nick, T. G., Frye, R. E., & James, S. J. (2012). Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain. Translational psychiatry, 2(7), e134. DOI: 10.1038/tp.2012.61

    Kerksick C, Willoughby D. The antioxidant role of glutathione and N-acetyl-cysteine supplements and exercise-induced oxidative stress. J Int Soc Sports Nutr. 2005;2(2):3844. Published 2005 Dec 9. doi: 10.1186/1550-2783-2-2-38Hakki Kalkan I, Suher M. The relationship between the level of glutathione, impairment of glucose metabolism and complications of diabetes mellitus. Pak J Med Sci. 2013;29(4):938942. doi: 10.12669/pjms.294.2859

    Tessier F, Margaritis I, Richard MJ, Moynot C, Marconnet P. Selenium and training effects on the glutathione system and aerobic performance. Medicine and Science in Sports and Exercise. 1995 Mar;27(3):390-396. PMID: 7752866

    Sacco, R., Eggenhoffner, R., & Giacomelli, L. (2016). Glutathione in the treatment of liver diseases: insights from clinical practice. Minerva gastroenterologica e dietologica, 62(4), 316324. PMID: 27603810

    Gibson SA, Korade Ž, Shelton RC. Oxidative stress and glutathione response in tissue cultures from persons with major depression. J Psychiatr Res. 2012;46(10):13261332. doi: 10.1016/j.jpsychires.2012.06.008

    Lapidus, K. A., Gabbay, V., Mao, X., Johnson, A., Murrough, J. W., Mathew, S. J., & Shungu, D. C. (2014). In vivo (1)H MRS study of potential associations between glutathione, oxidative stress and anhedonia in major depressive disorder. Neuroscience letters, 569, 7479. DOI: 10.1016/j.neulet.2014.03.056

    Adeoye O, Olawumi J, Opeyemi A, Christiania O. Review on the role of glutathione on oxidative stress and infertility. JBRA Assisted Reproduction. 2018 Mar;22(1):61-66. DOI: 10.5935/1518-0557.20180003

    Grucza, K., Chołbiński, P., Kwiatkowska, D., Szutowski, M.M., & Techasen, A. (2019). Effects of Supplementation with Glutathione and its Precursors on Athlete Performance. Biomedical Journal of Scientific and Technical Research, 12, 001-008. DOI: 10.26717/BJSTR.2019.12.002293

    Aoi W, Ogaya Y, Takami M, et al. Glutathione supplementation suppresses muscle fatigue induced by prolonged exercise via improved aerobic metabolism. J Int Soc Sports Nutr. 2015;12:7. Published 2015 Feb 6. doi: 10.1186/s12970-015-0067-x

    Buonocore D, Grosini M, Giardina S, et al. Bioavailability Study of an Innovative Orobuccal Formulation of Glutathione. Oxid Med Cell Longev. 2016;2016:3286365. doi: 10.1155/2016/3286365

    Chiang GC, Mao X, Kang G, et al. Relationships among Cortical Glutathione Levels, Brain Amyloidosis, and Memory in Healthy Older Adults Investigated In Vivo with 1H-MRS and Pittsburgh Compound-B PET. AJNR Am J Neuroradiol. 2017;38(6):11301137. doi: 10.3174/ajnr.A5143

    Dringen, R., & Hirrlinger, J. (2003). Glutathione pathways in the brain. Biological chemistry, 384(4), 505516. DOI: 10.1515/BC.2003.059

    Dwivedi, D., Megha, K., Mishra, R., & Mandal, P. K. (2020). Glutathione in Brain: Overview of Its Conformations, Functions, Biochemical Characteristics, Quantitation and Potential Therapeutic Role in Brain Disorders. Neurochemical research, 10.1007/s11064-020-03030-1. Advance online publication. DOI: 10.1007/s11064-020-03030-1

    Tong, J., Fitzmaurice, P. S., Moszczynska, A., Mattina, K., Ang, L. C., Boileau, I., Furukawa, Y., Sailasuta, N., & Kish, S. J. (2016). Do glutathione levels decline in aging human brain?. Free radical biology & medicine, 93, 110117. DOI: 10.1016/j.freeradbiomed.2016.01.029

    Sekhar R, Kumar P, Liu C. REVERSING AGING: PREVENTING AGE-RELATED DECLINE IN GLUTATHIONE AND MITOCHONDRIAL FUNCTION INCREASES LONGEVITY. Innov Aging. 2018;2(Suppl 1):887. Published 2018 Nov 16. doi: 10.1093/geroni/igy031.3309

    Fermented Organic Botanical Blend: Organic Apple Cider Vinegar, Organic Ginger Root (Zingiber officinale), Organic Turmeric Root (Curcuma longa), Deglycyrrhizinated Licorice Extract, L-Glutamine, Organic Marshmallow Root Powder, Probiotic Blend (1OB CFU†): B. clausil, B. coagulans, B. subtilis, S. boularadii. Other Ingredients: Methylcellulose Capsule.

    †At time of manufacture.

    Take 3 capsules daily with 8 ounces of water or your favorite beverage. May be taken with or without food.

    CAUTION: Do not exceed recommended dose. If you are allergic, or think you may be allergic to any of the listed ingredients, consult your primary healthcare physician before consuming. If you are pregnant, nursing, have a medical condition, or taking any medication, consult your doctor before using this product. If you experience an allergic reaction, please stop using the product immediately and contact your doctor. Do no exceed recommended dose. If your item appears to be damaged upon arrival, please contact us immediately. Additionally, if you experience any adverse reactions such as stomach pains, nausea, diarrhea, headache, rash, or others, please stop taking this product immediately and contact your doctor. Color and odor may vary from batch to batch. Contains no filler ingredients, artificial flavors, colors, sweeteners, or preservatives. Keep out of reach of children and pets. Use this product as a food supplement only. Do not use for weight reduction.

    Zinc

    Maggini S, Pierre A, Calder PC. Immune Function and Micronutrient Requirements Change over the Life Course. Nutrients. 2018;10(10):1531. Published 2018 Oct 17. doi: 10.3390/nu10101531

    Gombart AF, Pierre A, Maggini S. A Review of Micronutrients and the Immune System-Working in Harmony to Reduce the Risk of Infection. Nutrients. 2020;12(1):236. Published 2020 Jan 16. doi: 10.3390/nu12010236

    Prasad AS. Zinc in human health: effect of zinc on immune cells. Mol Med. 2008;14(5-6):353357. doi: 10.2119/2008-00033.Prasad

    Melissa L. Zastrow and Vincent L. Pecoraro. Designing Hydrolytic Zinc Metalloenzymes. Biochemistry 2014 53 (6), 957-978. February 7, 2014. DOI: 10.1021/bi4016617

    Technical University of Munich (TUM). "Diet lacking in zinc is detrimental to human, animal health: Even moderate zinc deficiency is bad for digestion." ScienceDaily. ScienceDaily, 9 June 2016.

    Organic Apple Cider Vinegar

    Johnston, C. S., & Gaas, C. A. (2006). Vinegar: medicinal uses and antiglycemic effect. MedGenMed : Medscape general medicine, 8(2), 61. PMID: 16926800

    Beh, B. K., Mohamad, N. E., Yeap, S. K., Ky, H., Boo, S. Y., Chua, J., Tan, S. W., Ho, W. Y., Sharifuddin, S. A., Long, K., & Alitheen, N. B. (2017). Anti-obesity and anti-inflammatory effects of synthetic acetic acid vinegar and Nipa vinegar on high-fat-diet-induced obese mice. Scientific reports, 7(1), 6664. doi: 10.1038/s41598-017-06235-7

    Santos, H. O., de Moraes, W., da Silva, G., Prestes, J., & Schoenfeld, B. J. (2019). Vinegar (acetic acid) intake on glucose metabolism: A narrative review. Clinical nutrition ESPEN, 32, 17. DOI: 10.1016/j.clnesp.2019.05.008

    Ostman, E., Granfeldt, Y., Persson, L., & Björck, I. (2005). Vinegar supplementation lowers glucose and insulin responses and increases satiety after a bread meal in healthy subjects. European journal of clinical nutrition, 59(9), 983988. DOI: 10.1038/sj.ejcn.1602197

    Shishehbor, F., Mansoori, A., & Shirani, F. (2017). Vinegar consumption can attenuate postprandial glucose and insulin responses; a systematic review and meta-analysis of clinical trials. Diabetes research and clinical practice, 127, 19. https://doi.org/10.1016/j.diabres.2017.01.021 DOI: 10.1016/j.diabres.2017.01.021

    Lim, J., Henry, C. J., & Haldar, S. (2016). Vinegar as a functional ingredient to improve postprandial glycemic control-human intervention findings and molecular mechanisms. Molecular nutrition & food research, 60(8), 18371849. DOI: 10.1002/mnfr.201600121

    Organic Turmeric Root

    Hewlings SJ, Kalman DS. Curcumin: A Review of Its' Effects on Human Health. Foods. 2017;6(10):92. Published 2017 Oct 22. doi.org/10.3390/foods6100092.

    Langhans, Sigrid. (2011). Therapeutic potential of curcumin in gastrointestinal diseases. World journal of gastrointestinal pathophysiology. 2. 1-14. DOI: 10.4291/wjgp.v2.i1.1

    Adrian L Lopresti, The Problem of Curcumin and Its Bioavailability: Could Its Gastrointestinal Influence Contribute to Its Overall Health-Enhancing Effects?, Advances in Nutrition, Volume 9, Issue 1, January 2018, Pages 4150, https://doi.org/10.1093/advances/nmx011

    Chainani-Wu N. (2003). Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa). Journal of alternative and complementary medicine (New York, N.Y.), 9(1), 161168. DOI: 10.1089/107555303321223035

    Zdrojewicz, Z., Szyca, M., Popowicz, E., Michalik, T., & Śmieszniak, B. (2017). Kurkuma nie tylko przyprawa [Turmeric - not only spice]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 42(252), 227230. PMID: 28662006

    Gupta, S. C., Sung, B., Kim, J. H., Prasad, S., Li, S., & Aggarwal, B. B. (2013). Multitargeting by turmeric, the golden spice: From kitchen to clinic. Molecular nutrition & food research, 57(9), 15101528. DOI: 10.1002/mnfr.201100741

    Deglycyrrhizinated Licorice Extract

    Hsu, Y. C., Chang, P. J., Tung, C. W., Shih, Y. H., Ni, W. C., Li, Y. C., Uto, T., Shoyama, Y., Ho, C., & Lin, C. L. (2020). De-Glycyrrhizinated Licorice Extract Attenuates High Glucose-Stimulated Renal Tubular Epithelial-Mesenchymal Transition via Suppressing the Notch2 Signaling Pathway. Cells, 9(1), 125. doi: 10.3390/cells9010125

    Messier, C., Epifano, F., Genovese, S., & Grenier, D. (2012). Licorice and its potential beneficial effects in common oro-dental diseases. Oral diseases, 18(1), 3239. DOI: 10.1111/j.1601-0825.2011.01842.x

    Dhiman, R. K., & Chawla, Y. K. (2005). Herbal medicines for liver diseases. Digestive diseases and sciences, 50(10), 18071812. DOI: 10.1007/s10620-005-2942-9

    Sun, Z. G., Zhao, T. T., Lu, N., Yang, Y. A., & Zhu, H. L. (2019). Research Progress of Glycyrrhizic Acid on Antiviral Activity. Mini reviews in medicinal chemistry, 19(10), 826832. DOI: 10.2174/1389557519666190119111125

    Raveendra, K. R., Jayachandra, Srinivasa, V., Sushma, K. R., Allan, J. J., Goudar, K. S., Shivaprasad, H. N., Venkateshwarlu, K., Geetharani, P., Sushma, G., & Agarwal, A. (2012). An Extract of Glycyrrhiza glabra (GutGard) Alleviates Symptoms of Functional Dyspepsia: A Randomized, Double-Blind, Placebo-Controlled Study. Evidence-based complementary and alternative medicine : eCAM, 2012, 216970. doi: 10.1155/2012/216970

    L-Glutamine

    Weschawalit S, Thongthip S, Phutrakool P, Asawanonda P. Glutathione and its antiaging and antimelanogenic effects. Clin Cosmet Investig Dermatol. 2017;10:147153. Published 2017 Apr 27. doi: 10.2147/CCID.S128339

    Gaucher C, Boudier A, Bonetti J, Clarot I, Leroy P, Parent M. Glutathione: Antioxidant Properties Dedicated to Nanotechnologies. Antioxidants (Basel). 2018;7(5):62. Published 2018 Apr 27. doi: 10.3390/antiox7050062

    Honda, Y., Kessoku, T., Sumida, Y., Kobayashi, T., Kato, T., Ogawa, Y., Tomeno, W., Imajo, K., Fujita, K., Yoneda, M., Kataoka, K., Taguri, M., Yamanaka, T., Seko, Y., Tanaka, S., Saito, S., Ono, M., Oeda, S., Eguchi, Y., Aoi, W., Nakajima, A. (2017). Efficacy of glutathione for the treatment of nonalcoholic fatty liver disease: an open-label, single-arm, multicenter, pilot study. BMC gastroenterology, 17(1), 96. DOI: 10.1186/s12876-017-0652-3

    Perricone, C., De Carolis, C., & Perricone, R. (2009). Glutathione: a key player in autoimmunity. Autoimmunity reviews, 8(8), 697701. DOI: 10.1016/j.autrev.2009.02.020

    Rose, S., Melnyk, S., Pavliv, O., Bai, S., Nick, T. G., Frye, R. E., & James, S. J. (2012). Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain. Translational psychiatry, 2(7), e134. DOI: 10.1038/tp.2012.61

    Kerksick C, Willoughby D. The antioxidant role of glutathione and N-acetyl-cysteine supplements and exercise-induced oxidative stress. J Int Soc Sports Nutr. 2005;2(2):3844. Published 2005 Dec 9. doi: 10.1186/1550-2783-2-2-38Hakki Kalkan I, Suher M. The relationship between the level of glutathione, impairment of glucose metabolism and complications of diabetes mellitus. Pak J Med Sci. 2013;29(4):938942. doi: 10.12669/pjms.294.2859

    Tessier F, Margaritis I, Richard MJ, Moynot C, Marconnet P. Selenium and training effects on the glutathione system and aerobic performance. Medicine and Science in Sports and Exercise. 1995 Mar;27(3):390-396. PMID: 7752866

    Sacco, R., Eggenhoffner, R., & Giacomelli, L. (2016). Glutathione in the treatment of liver diseases: insights from clinical practice. Minerva gastroenterologica e dietologica, 62(4), 316324. PMID: 27603810

    Gibson SA, Korade Ž, Shelton RC. Oxidative stress and glutathione response in tissue cultures from persons with major depression. J Psychiatr Res. 2012;46(10):13261332. doi: 10.1016/j.jpsychires.2012.06.008

    Lapidus, K. A., Gabbay, V., Mao, X., Johnson, A., Murrough, J. W., Mathew, S. J., & Shungu, D. C. (2014). In vivo (1)H MRS study of potential associations between glutathione, oxidative stress and anhedonia in major depressive disorder. Neuroscience letters, 569, 7479. DOI: 10.1016/j.neulet.2014.03.056

    Adeoye O, Olawumi J, Opeyemi A, Christiania O. Review on the role of glutathione on oxidative stress and infertility. JBRA Assisted Reproduction. 2018 Mar;22(1):61-66. DOI: 10.5935/1518-0557.20180003

    Grucza, K., Chołbiński, P., Kwiatkowska, D., Szutowski, M.M., & Techasen, A. (2019). Effects of Supplementation with Glutathione and its Precursors on Athlete Performance. Biomedical Journal of Scientific and Technical Research, 12, 001-008. DOI: 10.26717/BJSTR.2019.12.002293

    Aoi W, Ogaya Y, Takami M, et al. Glutathione supplementation suppresses muscle fatigue induced by prolonged exercise via improved aerobic metabolism. J Int Soc Sports Nutr. 2015;12:7. Published 2015 Feb 6. doi: 10.1186/s12970-015-0067-x

    Buonocore D, Grosini M, Giardina S, et al. Bioavailability Study of an Innovative Orobuccal Formulation of Glutathione. Oxid Med Cell Longev. 2016;2016:3286365. doi: 10.1155/2016/3286365

    Chiang GC, Mao X, Kang G, et al. Relationships among Cortical Glutathione Levels, Brain Amyloidosis, and Memory in Healthy Older Adults Investigated In Vivo with 1H-MRS and Pittsburgh Compound-B PET. AJNR Am J Neuroradiol. 2017;38(6):11301137. doi: 10.3174/ajnr.A5143

    Dringen, R., & Hirrlinger, J. (2003). Glutathione pathways in the brain. Biological chemistry, 384(4), 505516. DOI: 10.1515/BC.2003.059

    Dwivedi, D., Megha, K., Mishra, R., & Mandal, P. K. (2020). Glutathione in Brain: Overview of Its Conformations, Functions, Biochemical Characteristics, Quantitation and Potential Therapeutic Role in Brain Disorders. Neurochemical research, 10.1007/s11064-020-03030-1. Advance online publication. DOI: 10.1007/s11064-020-03030-1

    Tong, J., Fitzmaurice, P. S., Moszczynska, A., Mattina, K., Ang, L. C., Boileau, I., Furukawa, Y., Sailasuta, N., & Kish, S. J. (2016). Do glutathione levels decline in aging human brain?. Free radical biology & medicine, 93, 110117. DOI: 10.1016/j.freeradbiomed.2016.01.029

    Sekhar R, Kumar P, Liu C. REVERSING AGING: PREVENTING AGE-RELATED DECLINE IN GLUTATHIONE AND MITOCHONDRIAL FUNCTION INCREASES LONGEVITY. Innov Aging. 2018;2(Suppl 1):887. Published 2018 Nov 16. doi: 10.1093/geroni/igy031.3309

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    Customer Reviews
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    SF
    12/08/2022
    Samantha F.
    United States

    Leaky gut pills

    These pills really have helped me and reduced my bloating

    BR
    10/09/2022
    Becky R.
    United States United States

    Amén Leaky Gut & Codeage Collagen

    Very good quality products. I was concerned about the price until I compared serving sizes and impact to other brands - turns out these are no more expensive because there are more servings per container. Made me a subscriber - for quality and serving sizes, I’m happy with the products. (For transparency, they did ask me for a review after my third bottle of the Amen Leaky Gut and offered a $5 coupon if I took the time to review. The did ask for a review in the collagen but i like that one too)

    TM
    09/28/2022
    Timothy M.
    United States United States

    Short and long term relief

    Don't let the name fool you. It brings short term relief while helping to heal deep seated issue over time.

    7W
    09/26/2022
    74 with bowel swings from constipation to diarrhea my entire life. This product resolved all problems within the first 48 hours. Gave up my prescription med for this supplement.

    Leaky gut is #1 for gut health

    Great product. Great site. Great price with subscription. Looking forward to the other benefits of this supplement like skin and mood swings. I highly recommend this supplement.

    LC
    09/15/2022
    Laura C.
    United States United States

    Digestive help

    Seems to help with digestive issues, along with diet changes. I still get bloating, but doesn’t seem as bad.

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