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Amen Leaky Gut +

For Gut & Digestion
$22.99
50 reviews
Bestseller

Description

PRODUCT DETAILS

  • Zinc
  • Fermented organic botanical blend
  • Organic apple cider vinegar
  • Organic ginger root
  • Organic turmeric root
  • L-glutamine
  • Organic marshmallow root powder
  • Probiotic blend (10 billion CFUs)*
  • Licorice extract
  • Veggie capsules
  • Fermented
  • Vegan & non-GMO
  • Paleo friendly, gluten-free
  • 1 month supply
  • 30-day money-back guarantee
  • Manufactured in the USA in a cGMP certified facility
  • Third party tested

FEATURED INGREDIENTS

Zinc

15 mg

Organic Apple Cider Vinegar

Acetic acid

Organic Turmeric Root

From the ginger family

Deglycyrrhizinated Licorice Extract

Licorice contains flavonoids & phytoestrogens

L-Glutamine

An important amino acid

The right gut feeling

Our gut deserves a unique care. It’s an important building block to a healthy you. Amen Leaky Gut provides a combination of prebiotics, probiotics, zinc, and L-glutamine.

Support intestinal wellness from within*

Vegan. Non-GMO. Manufactured in a cGMP facility in the USA. 3rd party tested.

Supplement Facts

Ingredients

Suggested Use

References

PRODUCT DETAILS

  • Zinc
  • Fermented organic botanical blend
  • Organic apple cider vinegar
  • Organic ginger root
  • Organic turmeric root
  • L-glutamine
  • Organic marshmallow root powder
  • Probiotic blend (10 billion CFUs)*
  • Licorice extract
  • Veggie capsules
  • Fermented
  • Vegan & non-GMO
  • Paleo friendly, gluten-free
  • 1 month supply
  • 30-day money-back guarantee
  • Manufactured in the USA in a cGMP certified facility
  • Third party tested

FEATURED INGREDIENTS

Zinc

15 mg

Organic Apple Cider Vinegar

Acetic acid

Organic Turmeric Root

From the ginger family

Deglycyrrhizinated Licorice Extract

Licorice contains flavonoids & phytoestrogens

L-Glutamine

An important amino acid

The right gut feeling

Our gut deserves a unique care. It’s an important building block to a healthy you. Amen Leaky Gut provides a combination of prebiotics, probiotics, zinc, and L-glutamine.

Support intestinal wellness from within*

Vegan. Non-GMO. Manufactured in a cGMP facility in the USA. 3rd party tested.

Zinc (as Citrate), Fermented Organic Botanical Blend: Organic Apple Cider Vinegar, Organic Ginger Root (Zingiber officinale), Organic Turmeric Root (Curcuma longa), Deglycyrrhizinated Licorice Extract, L-Glutamine, Organic Marshmallow Root Powder, Probiotic Blend (10B CFU): B. clausii, B. coagulans, B. subtilis, S. boulardi.

*Formulated with 10 Billion CFUs at the time of manufacturing.

Take 3 capsules daily with 8 ounces of water or your favorite beverage. May be taken with or without food.

CAUTION: Do not exceed recommended dose. If you are allergic, or think you may be allergic to any of the listed ingredients, consult your primary healthcare physician before consuming. If you are pregnant, nursing, have a medical condition, or taking any medication, consult your doctor before using this product. If you experience an allergic reaction, please stop using the product immediately and contact your doctor. Do no exceed recommended dose. If your item appears to be damaged upon arrival, please contact us immediately. Additionally, if you experience any adverse reactions such as stomach pains, nausea, diarrhea, headache, rash, or others, please stop taking this product immediately and contact your doctor. Color and odor may vary from batch to batch. Contains no filler ingredients, artificial flavors, colors, sweeteners, or preservatives. Keep out of reach of children and pets. Use this product as a food supplement only. Do not use for weight reduction.

Zinc

Maggini S, Pierre A, Calder PC. Immune Function and Micronutrient Requirements Change over the Life Course. Nutrients. 2018;10(10):1531. Published 2018 Oct 17. doi: 10.3390/nu10101531

Gombart AF, Pierre A, Maggini S. A Review of Micronutrients and the Immune System-Working in Harmony to Reduce the Risk of Infection. Nutrients. 2020;12(1):236. Published 2020 Jan 16. doi: 10.3390/nu12010236

Prasad AS. Zinc in human health: effect of zinc on immune cells. Mol Med. 2008;14(5-6):353357. doi: 10.2119/2008-00033.Prasad

Melissa L. Zastrow and Vincent L. Pecoraro. Designing Hydrolytic Zinc Metalloenzymes. Biochemistry 2014 53 (6), 957-978. February 7, 2014. DOI: 10.1021/bi4016617

Technical University of Munich (TUM). "Diet lacking in zinc is detrimental to human, animal health: Even moderate zinc deficiency is bad for digestion." ScienceDaily. ScienceDaily, 9 June 2016.

Organic Apple Cider Vinegar

Johnston, C. S., & Gaas, C. A. (2006). Vinegar: medicinal uses and antiglycemic effect. MedGenMed : Medscape general medicine, 8(2), 61. PMID: 16926800

Beh, B. K., Mohamad, N. E., Yeap, S. K., Ky, H., Boo, S. Y., Chua, J., Tan, S. W., Ho, W. Y., Sharifuddin, S. A., Long, K., & Alitheen, N. B. (2017). Anti-obesity and anti-inflammatory effects of synthetic acetic acid vinegar and Nipa vinegar on high-fat-diet-induced obese mice. Scientific reports, 7(1), 6664. doi: 10.1038/s41598-017-06235-7

Santos, H. O., de Moraes, W., da Silva, G., Prestes, J., & Schoenfeld, B. J. (2019). Vinegar (acetic acid) intake on glucose metabolism: A narrative review. Clinical nutrition ESPEN, 32, 17. DOI: 10.1016/j.clnesp.2019.05.008

Ostman, E., Granfeldt, Y., Persson, L., & Björck, I. (2005). Vinegar supplementation lowers glucose and insulin responses and increases satiety after a bread meal in healthy subjects. European journal of clinical nutrition, 59(9), 983988. DOI: 10.1038/sj.ejcn.1602197

Shishehbor, F., Mansoori, A., & Shirani, F. (2017). Vinegar consumption can attenuate postprandial glucose and insulin responses; a systematic review and meta-analysis of clinical trials. Diabetes research and clinical practice, 127, 19. https://doi.org/10.1016/j.diabres.2017.01.021 DOI: 10.1016/j.diabres.2017.01.021

Lim, J., Henry, C. J., & Haldar, S. (2016). Vinegar as a functional ingredient to improve postprandial glycemic control-human intervention findings and molecular mechanisms. Molecular nutrition & food research, 60(8), 18371849. DOI: 10.1002/mnfr.201600121

Organic Turmeric Root

Hewlings SJ, Kalman DS. Curcumin: A Review of Its' Effects on Human Health. Foods. 2017;6(10):92. Published 2017 Oct 22. doi.org/10.3390/foods6100092.

Langhans, Sigrid. (2011). Therapeutic potential of curcumin in gastrointestinal diseases. World journal of gastrointestinal pathophysiology. 2. 1-14. DOI: 10.4291/wjgp.v2.i1.1

Adrian L Lopresti, The Problem of Curcumin and Its Bioavailability: Could Its Gastrointestinal Influence Contribute to Its Overall Health-Enhancing Effects?, Advances in Nutrition, Volume 9, Issue 1, January 2018, Pages 4150, https://doi.org/10.1093/advances/nmx011

Chainani-Wu N. (2003). Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa). Journal of alternative and complementary medicine (New York, N.Y.), 9(1), 161168. DOI: 10.1089/107555303321223035

Zdrojewicz, Z., Szyca, M., Popowicz, E., Michalik, T., & Śmieszniak, B. (2017). Kurkuma nie tylko przyprawa [Turmeric - not only spice]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 42(252), 227230. PMID: 28662006

Gupta, S. C., Sung, B., Kim, J. H., Prasad, S., Li, S., & Aggarwal, B. B. (2013). Multitargeting by turmeric, the golden spice: From kitchen to clinic. Molecular nutrition & food research, 57(9), 15101528. DOI: 10.1002/mnfr.201100741

Deglycyrrhizinated Licorice Extract

Hsu, Y. C., Chang, P. J., Tung, C. W., Shih, Y. H., Ni, W. C., Li, Y. C., Uto, T., Shoyama, Y., Ho, C., & Lin, C. L. (2020). De-Glycyrrhizinated Licorice Extract Attenuates High Glucose-Stimulated Renal Tubular Epithelial-Mesenchymal Transition via Suppressing the Notch2 Signaling Pathway. Cells, 9(1), 125. doi: 10.3390/cells9010125

Messier, C., Epifano, F., Genovese, S., & Grenier, D. (2012). Licorice and its potential beneficial effects in common oro-dental diseases. Oral diseases, 18(1), 3239. DOI: 10.1111/j.1601-0825.2011.01842.x

Dhiman, R. K., & Chawla, Y. K. (2005). Herbal medicines for liver diseases. Digestive diseases and sciences, 50(10), 18071812. DOI: 10.1007/s10620-005-2942-9

Sun, Z. G., Zhao, T. T., Lu, N., Yang, Y. A., & Zhu, H. L. (2019). Research Progress of Glycyrrhizic Acid on Antiviral Activity. Mini reviews in medicinal chemistry, 19(10), 826832. DOI: 10.2174/1389557519666190119111125

Raveendra, K. R., Jayachandra, Srinivasa, V., Sushma, K. R., Allan, J. J., Goudar, K. S., Shivaprasad, H. N., Venkateshwarlu, K., Geetharani, P., Sushma, G., & Agarwal, A. (2012). An Extract of Glycyrrhiza glabra (GutGard) Alleviates Symptoms of Functional Dyspepsia: A Randomized, Double-Blind, Placebo-Controlled Study. Evidence-based complementary and alternative medicine : eCAM, 2012, 216970. doi: 10.1155/2012/216970

L-Glutamine

Weschawalit S, Thongthip S, Phutrakool P, Asawanonda P. Glutathione and its antiaging and antimelanogenic effects. Clin Cosmet Investig Dermatol. 2017;10:147153. Published 2017 Apr 27. doi: 10.2147/CCID.S128339

Gaucher C, Boudier A, Bonetti J, Clarot I, Leroy P, Parent M. Glutathione: Antioxidant Properties Dedicated to Nanotechnologies. Antioxidants (Basel). 2018;7(5):62. Published 2018 Apr 27. doi: 10.3390/antiox7050062

Honda, Y., Kessoku, T., Sumida, Y., Kobayashi, T., Kato, T., Ogawa, Y., Tomeno, W., Imajo, K., Fujita, K., Yoneda, M., Kataoka, K., Taguri, M., Yamanaka, T., Seko, Y., Tanaka, S., Saito, S., Ono, M., Oeda, S., Eguchi, Y., Aoi, W., Nakajima, A. (2017). Efficacy of glutathione for the treatment of nonalcoholic fatty liver disease: an open-label, single-arm, multicenter, pilot study. BMC gastroenterology, 17(1), 96. DOI: 10.1186/s12876-017-0652-3

Perricone, C., De Carolis, C., & Perricone, R. (2009). Glutathione: a key player in autoimmunity. Autoimmunity reviews, 8(8), 697701. DOI: 10.1016/j.autrev.2009.02.020

Rose, S., Melnyk, S., Pavliv, O., Bai, S., Nick, T. G., Frye, R. E., & James, S. J. (2012). Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain. Translational psychiatry, 2(7), e134. DOI: 10.1038/tp.2012.61

Kerksick C, Willoughby D. The antioxidant role of glutathione and N-acetyl-cysteine supplements and exercise-induced oxidative stress. J Int Soc Sports Nutr. 2005;2(2):3844. Published 2005 Dec 9. doi: 10.1186/1550-2783-2-2-38Hakki Kalkan I, Suher M. The relationship between the level of glutathione, impairment of glucose metabolism and complications of diabetes mellitus. Pak J Med Sci. 2013;29(4):938942. doi: 10.12669/pjms.294.2859

Tessier F, Margaritis I, Richard MJ, Moynot C, Marconnet P. Selenium and training effects on the glutathione system and aerobic performance. Medicine and Science in Sports and Exercise. 1995 Mar;27(3):390-396. PMID: 7752866

Sacco, R., Eggenhoffner, R., & Giacomelli, L. (2016). Glutathione in the treatment of liver diseases: insights from clinical practice. Minerva gastroenterologica e dietologica, 62(4), 316324. PMID: 27603810

Gibson SA, Korade Ž, Shelton RC. Oxidative stress and glutathione response in tissue cultures from persons with major depression. J Psychiatr Res. 2012;46(10):13261332. doi: 10.1016/j.jpsychires.2012.06.008

Lapidus, K. A., Gabbay, V., Mao, X., Johnson, A., Murrough, J. W., Mathew, S. J., & Shungu, D. C. (2014). In vivo (1)H MRS study of potential associations between glutathione, oxidative stress and anhedonia in major depressive disorder. Neuroscience letters, 569, 7479. DOI: 10.1016/j.neulet.2014.03.056

Adeoye O, Olawumi J, Opeyemi A, Christiania O. Review on the role of glutathione on oxidative stress and infertility. JBRA Assisted Reproduction. 2018 Mar;22(1):61-66. DOI: 10.5935/1518-0557.20180003

Grucza, K., Chołbiński, P., Kwiatkowska, D., Szutowski, M.M., & Techasen, A. (2019). Effects of Supplementation with Glutathione and its Precursors on Athlete Performance. Biomedical Journal of Scientific and Technical Research, 12, 001-008. DOI: 10.26717/BJSTR.2019.12.002293

Aoi W, Ogaya Y, Takami M, et al. Glutathione supplementation suppresses muscle fatigue induced by prolonged exercise via improved aerobic metabolism. J Int Soc Sports Nutr. 2015;12:7. Published 2015 Feb 6. doi: 10.1186/s12970-015-0067-x

Buonocore D, Grosini M, Giardina S, et al. Bioavailability Study of an Innovative Orobuccal Formulation of Glutathione. Oxid Med Cell Longev. 2016;2016:3286365. doi: 10.1155/2016/3286365

Chiang GC, Mao X, Kang G, et al. Relationships among Cortical Glutathione Levels, Brain Amyloidosis, and Memory in Healthy Older Adults Investigated In Vivo with 1H-MRS and Pittsburgh Compound-B PET. AJNR Am J Neuroradiol. 2017;38(6):11301137. doi: 10.3174/ajnr.A5143

Dringen, R., & Hirrlinger, J. (2003). Glutathione pathways in the brain. Biological chemistry, 384(4), 505516. DOI: 10.1515/BC.2003.059

Dwivedi, D., Megha, K., Mishra, R., & Mandal, P. K. (2020). Glutathione in Brain: Overview of Its Conformations, Functions, Biochemical Characteristics, Quantitation and Potential Therapeutic Role in Brain Disorders. Neurochemical research, 10.1007/s11064-020-03030-1. Advance online publication. DOI: 10.1007/s11064-020-03030-1

Tong, J., Fitzmaurice, P. S., Moszczynska, A., Mattina, K., Ang, L. C., Boileau, I., Furukawa, Y., Sailasuta, N., & Kish, S. J. (2016). Do glutathione levels decline in aging human brain?. Free radical biology & medicine, 93, 110117. DOI: 10.1016/j.freeradbiomed.2016.01.029

Sekhar R, Kumar P, Liu C. REVERSING AGING: PREVENTING AGE-RELATED DECLINE IN GLUTATHIONE AND MITOCHONDRIAL FUNCTION INCREASES LONGEVITY. Innov Aging. 2018;2(Suppl 1):887. Published 2018 Nov 16. doi: 10.1093/geroni/igy031.3309

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Customer Reviews
4.8 Based on 50 Reviews
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SG
01/23/2022
Susan G.
United States United States

Good stuff

I have had acid reflux for years. I believe the Leaky Gut pill is helping along with low acidic foods and no dairy.

AW
01/16/2022
Arthur W.
United States United States

So far it has been the only thing that has made a difference. Will order again

JB
01/09/2022
Jaime B.
United States United States

Healed and Continues to Help

I am pretty sure this supplement along with removing wheat/gluten has helped me to heal my leaky gut. I continue to take it daily to help with bloating and pain. Will continue to use this supplement.

GT
01/07/2022
Gloria T.
United States United States

THE BEST

I have had issues with my stomach for over 40 years, it started as a child when I was 14. I was diagnosed with Gastritis as a teenager then diagnosed with (SIBO) a small intestinal bacteria overgrowth in my late twenties. I have tried probaly every stomach product on the market. The Gastrologist Specialist prescribed an antibiotic name Xifaxan, it actually worked for a few years. I would get a real bad flare up once a year and take them for 10 to 14 days but it stopped working. I was always so bloated, I couldn't eat but once day, and just felt miserable from the time I get up until bedtime. It seems like I've been bloated all my life and it prevented me from doing many things. I was watching the PBS channel one night and this show came on with Dr.Amen, he talked about what food you can eat to help with your ailments. I found it to be very interesting so I looked him up and started reading about him and came across LEAKY GUT. I am sooooo glad that I watched his show because I would have never found this. After a couple of weeks of taking this, the bloated feeling started to subside. I can now eat 3 times a day but not full meals yet. This is the best product I have ever had that actually works.

LD
12/23/2021
Linda D.
United States United States

The product works

Both my husband and I take this product. It has greatly helped our digestive problems.

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