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1-856-CODEAGE
- 1285 mg of vitamin C
- 15 mg of zinc
- Bioflavonoids:Ā this daily vitamin c formula features citrus bioflavonoids, including grapefruit, lemon, and orange powders
- Elderberry extract
- Quercetin
- Rose hips extract fruit
- Vegan
- Veggie capsules
- Milk, wheat & soy-free
- Paleo & keto friendly
- Non-GMO and gluten-free
- 2-month supply
- Manufactured in the USA in a cGMP facility
- Third-party tested
Amen Vitamin C+
Vitamin C, Zinc, And Citrus Bioflavonoids All-In-One
$22.99
Vitamin C Complex
Description
Product Details
Featured Ingredients
Vitamin C Complex
1285 mg
Citrus Bioflavonoids
Grapefruit, lemon and orange powders
Elderberry Powder
A source of vitamins
Quercetin
Flavonoid & plant pigment
Zinc
15 mg
2 months supply
Vegan and non-GMO Vitamin C capsule solution featuring citrus bioflavonoids, quercetin, rose hips, elderberry extracts, and zinc all-in-one.
Suggested use
Adults take 2 capsules daily with 8 ounces of water or your favorite beverage.Ā May be taken with or without food.
See caution
CAUTION: Do not exceed recommended dose. Please use caution if you have allergies or sensitivities to any of the listed ingredients. Pregnant or nursing mothers and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Use only as directed. If gastrointestinal discomfort (including bloating, cramps, diarrhea, or other digestive upset) or other sensitivity is experienced stop taking the product immediately. If you are pregnant, nursing, or have a medical condition, please consult with your physician before use. If you have any questions about consuming this dietary supplement, consult with your health care professional before using. If you use prescription drugs or over-the-counter medications, are unaware of your current medical condition or have a pre-existing medical condition(s), consult with your health care professional before using. Discontinue use immediately if you experience any adverse symptoms or reactions while taking this product. Discontinue use 2 weeks prior to surgery. Do not use if your health status is unknown. Do not use if safety seal is damaged or missing. Keep out of reach of children and pets. Store in a cool, dry place, away from heat moisture. Use this product as a food supplement only. Do not use for weight reduction.
Additional Details
2 months supply
Vegan and non-GMO Vitamin C capsule solution featuring citrus bioflavonoids, quercetin, rose hips, elderberry extracts, and zinc all-in-one.
See all ingredients
Ingredients:
Vitamin C (as Ascorbic Acid), Zinc (as Zinc Amino Acid Chelate), Citrus Bioflavonoid Complex: Grapefruit Powder (Fruit), Lemon Powder (Peel), Orange Powder (Fruit), Quercetin Dihydrate, Rose Hips Extract (Fruit), Elderberry Extract (Fruit; Std. to 5% Flavanoids). Other Ingredients: Methylcellulose Capsule.
Pairs With
References
Vitamin C Complex
Chambial S, Dwivedi S, Shukla KK, John PJ, Sharma P. Vitamin C in disease prevention and cure: an overview. Indian J Clin Biochem. 2013;28(4):314ā328. doi: 10.1007/s12291-013-0375-3
Traber MG, Stevens JF. Vitamins C and E: beneficial effects from a mechanistic perspective. Free Radic Biol Med. 2011;51(5):1000ā1013. doi: 10.1016/j.freeradbiomed.2011.05.017
See more
Padayatty, S. J., Katz, A., Wang, Y., Eck, P., Kwon, O., Lee, J. H., Chen, S., Corpe, C., Dutta, A., Dutta, S. K., & Levine, M. (2003). Vitamin C as an antioxidant: evaluation of its role in disease prevention. Journal of the American College of Nutrition, 22(1), 18ā35. DOI: 10.1080/07315724.2003.10719272
Pehlivan, Fadime. (2017). Vitamin C: An Antioxidant Agent. 10.5772/intechopen.69660. DOI: 10.5772/intechopen.69660
A. Bendich, L.J. Machlin, O. Scandurra, G.W. Burton, D.D.M. Wayner, The antioxidant role of vitamin C, Advances in Free Radical Biology & Medicine, Volume 2, Issue 2, 1986, 419-444, 8755-9668. https://doi.org/10.1016/S8755-9668(86)80021-7
Marc BĆ¼rzle, Matthias A. Hediger. Chapter Eleven: Functional and Physiological Role of Vitamin C Transporters. Mark O. Bevensee. Current Topics in Membranes. Academic Press. 70. 2012. 357-375. 1063-5823. 9780123943163. https://doi.org/10.1016/B978-0-12-394316-3.00011-9
Akbari, Abolfazl & Jelodar, Gholamali & Nazifi, Saeed & Sajedianfard, Javad. (2016). An Overview of The characteristics and Function of Vitamin C in Various Tissues: Relying on its Antioxidant Function. Zahedan Journal of Research in Medical Sciences. In Press. DOI: 10.17795/zjrms-4037
Chakraborthy, Aratirika & Ramani, Pratibha & Sherlin, Herald & Premkumar, Priya & Natesan, Anuja. (2014). Antioxidant and pro-oxidant activity of Vitamin C in oral environment. Indian journal of dental research : official publication of Indian Society for Dental Research. 25. 499-504. DOI: 10.4103/0970-9290.142547
Sirmali, Rana & GiniÅ, Zeynep & Sirmali, Mehmet & Solak, Okan & Åeliman, BengĆ¼ & AÄaƧkiran, Yetkin & DelibaÅ, Namık. (2014). Vitamin C as an antioxidant: evaluation of its role on pulmonary contusion experimental model. Turkish journal of medical sciences. 44. 905-13. DOI: 10.3906/sag-1309-139
Citrus Bioflavonoids
Stevens, Y., Rymenant, E. V., Grootaert, C., Camp, J. V., Possemiers, S., Masclee, A., & Jonkers, D. (2019). The Intestinal Fate of Citrus Flavanones and Their Effects on Gastrointestinal Health. Nutrients, 11(7), 1464. DOI: 10.3390/nu11071464
Testai L, Calderone V. Nutraceutical Value of Citrus Flavanones and Their Implications in Cardiovascular Disease. Nutrients. 2017;9(5):502. Published 2017 May 16. doi: 10.3390/nu9050502
Barreca, D., Gattuso, G., Bellocco, E., Calderaro, A., Trombetta, D., Smeriglio, A., LaganĆ , G., Daglia, M., Meneghini, S., & Nabavi, S. M. (2017). Flavanones: Citrus phytochemical with health-promoting properties. BioFactors (Oxford, England), 43(4), 495ā506. DOI: 10.1002/biof.1363
Sharma, M., Akhtar, N., Sambhav, K., Shete, G., Bansal, A. K., & Sharma, S. S. (2015). Emerging potential of citrus flavanones as an antioxidant in diabetes and its complications. Current topics in medicinal chemistry, 15(2), 187ā195. DOI: 10.2174/1568026615666141209163013
Chanet, A., Milenkovic, D., Manach, C., Mazur, A., & Morand, C. (2012). Citrus flavanones: what is their role in cardiovascular protection?. Journal of agricultural and food chemistry, 60(36), 8809ā8822. DOI: 10.1021/jf300669s
Zaidun, N. H., Thent, Z. C., & Latiff, A. A. (2018). Combating oxidative stress disorders with citrus flavonoid: Naringenin. Life sciences, 208, 111ā122. DOI: 10.1016/j.lfs.2018.07.017
Assini, J. M., Mulvihill, E. E., & Huff, M. W. (2013). Citrus flavonoids and lipid metabolism. Current opinion in lipidology, 24(1), 34ā40. DOI: 10.1097/MOL.0b013e32835c07fd
Asgary, S., Naderi, G., & Askari, N. (2005). Protective effect of flavonoids against red blood cell hemolysis by free radicals. Experimental and clinical cardiology, 10(2), 88ā90. PMCID: PMC2716227
Elderberry Powder
Sidor, Andrzej & Gramza Michalowska, Anna. (2014). Advanced research on the antioxidant and health benefit of elderberry (Sambucus nigra) in food ā a review. Journal of Functional Foods. 18. DOI: 10.1016/j.jff.2014.07.012
Porter, R. S., & Bode, R. F. (2017). A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products. Phytotherapy research : PTR, 31(4), 533ā554. DOI: 10.1002/ptr.5782
Zakay-Rones, Z., Thom, E., Wollan, T., & Wadstein, J. (2004). Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections. The Journal of international medical research, 32(2), 132ā140. DOI: 10.1177/147323000403200205
Barak, V., Halperin, T., & Kalickman, I. (2001). The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. European cytokine network, 12(2), 290ā296. PMID: 11399518
Hawkins, J., Baker, C., Cherry, L., & Dunne, E. (2019). Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials. Complementary therapies in medicine, 42, 361ā365. DOI: 10.1016/j.ctim.2018.12.004
Tiralongo E, Wee SS, Lea RA. Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial. Nutrients. 2016;8(4):182. Published 2016 Mar 24. doi: 10.3390/nu8040182
Porter, R. S., & Bode, R. F. (2017). A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products. Phytotherapy research : PTR, 31(4), 533ā554. DOI: 10.1002/ptr.5782
Quercetin
Selamoglu, Zeliha. (2016). Antioxidant Activity of Quercetin: A Mechanistic Review. Turkish Journal of Agriculture - Food Science and Technology. 4. 10.24925/turjaf.v4i12.1134-1138.1069. DOI: 10.24925/turjaf.v4i12.1134-1138.1069
Anand David AV, Arulmoli R, Parasuraman S. Overviews of Biological Importance of Quercetin: A Bioactive Flavonoid. Pharmacogn Rev. 2016;10(20):84ā89. doi: 10.4103/0973-7847.194044
Serban, M. C., Sahebkar, A., Zanchetti, A., Mikhailidis, D. P., Howard, G., Antal, D., Andrica, F., Ahmed, A., Aronow, W. S., Muntner, P., Lip, G. Y., Graham, I., Wong, N., Rysz, J., Banach, M., & Lipid and Blood Pressure Metaāanalysis Collaboration (LBPMC) Group (2016). Effects of Quercetin on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Journal of the American Heart Association, 5(7), e002713. DOI: 10.1161/JAHA.115.002713
Xu D, Hu MJ, Wang YQ, Cui YL. Antioxidant Activities of Quercetin and Its Complexes for Medicinal Application. Molecules. 2019;24(6):1123. Published 2019 Mar 21. doi: 10.3390/molecules24061123
AlĆa, M., Mateos, R., Ramos, S., Lecumberri, E., Bravo, L., & Goya, L. (2006). Influence of quercetin and rutin on growth and antioxidant defense system of a human hepatoma cell line (HepG2). European journal of nutrition, 45(1), 19ā28. DOI: 10.1007/s00394-005-0558-7
Robaszkiewicz, A., Balcerczyk, A., & Bartosz, G. (2007). Antioxidative and prooxidative effects of quercetin on A549 cells. Cell biology international, 31(10), 1245ā1250. DOI: 10.1016/j.cellbi.2007.04.009
Kim, G. N., & Jang, H. D. (2009). Protective mechanism of quercetin and rutin using glutathione metabolism on HO-induced oxidative stress in HepG2 cells. Annals of the New York Academy of Sciences, 1171, 530ā537. DOI: 10.1111/j.1749-6632.2009.04690.x
Baghel, Satyendra & Shrivastava, Nikhil & Baghel, PA & Rajput, Sarlesh. (2012). A review of quercetin: Antioxidant and anticancer properties. World J Pharm Pharmaceutical Sci. 1. 146 - 160.
Zinc
Kaltenberg, J., Plum, L. M., Ober-Blƶbaum, J. L., Hƶnscheid, A., Rink, L., & Haase, H. (2010). Zinc signals promote IL-2-dependent proliferation of T cells. European journal of immunology, 40(5), 1496ā1503. DOI: 10.1002/eji.200939574
Shankar, A. H., & Prasad, A. S. (1998). Zinc and immune function: the biological basis of altered resistance to infection. The American journal of clinical nutrition, 68(2 Suppl), 447Sā463S. DOI: 10.1093/ajcn/68.2.447S
Barnett, J. B., Dao, M. C., Hamer, D. H., Kandel, R., Brandeis, G., Wu, D., Dallal, G. E., Jacques, P. F., Schreiber, R., Kong, E., & Meydani, S. N. (2016). Effect of zinc supplementation on serum zinc concentration and T cell proliferation in nursing home elderly: a randomized, double-blind, placebo-controlled trial. The American journal of clinical nutrition, 103(3), 942ā951. DOI: 10.3945/ajcn.115.115188
Barnett JB, Hamer DH, Meydani SN. Low zinc status: a new risk factor for pneumonia in the elderly? Nutrition Reviews. 2010 Jan;68(1):30-37. DOI: 10.1111/j.1753-4887.2009.00253.x
Yasuda, Hiroshi. (2017). The Situation of Zinc Deficiency: Early Assessment and Intervention Are Essential. Biomedical Research on Trace Elements. 125-140. DOI: 10.11299/brte.27.125
HemilƤ H. Zinc lozenges may shorten the duration of colds: a systematic review. Open Respir Med J. 2011;5:51ā58. doi: 10.2174/1874306401105010051
Rerksuppaphol, S., & Rerksuppaphol, L. (2013). A randomized controlled trial of chelated zinc for prevention of the common cold in Thai school children. Paediatrics and international child health, 33(3), 145ā150. DOI: 10.1179/2046905513Y.0000000064
Supplement Facts
Ingredients
Suggested Use
References
Product Details
- 1285 mg of vitamin C
- 15 mg of zinc
- Bioflavonoids:Ā this daily vitamin c formula features citrus bioflavonoids, including grapefruit, lemon, and orange powders
- Elderberry extract
- Quercetin
- Rose hips extract fruit
- Vegan
- Veggie capsules
- Milk, wheat & soy-free
- Paleo & keto friendly
- Non-GMO and gluten-free
- 2-month supply
- Manufactured in the USA in a cGMP facility
- Third-party tested
Featured Ingredients
Vitamin C Complex
1285 mg
Citrus Bioflavonoids
Grapefruit, lemon and orange powders
Elderberry Powder
A source of vitamins
Quercetin
Flavonoid & plant pigment
Zinc
15 mg
2 months supply
Vegan and non-GMO Vitamin C capsule solution featuring citrus bioflavonoids, quercetin, rose hips, elderberry extracts, and zinc all-in-one.
Suggested use
Adults take 2 capsules daily with 8 ounces of water or your favorite beverage.Ā May be taken with or without food.
See caution
CAUTION: Do not exceed recommended dose. Please use caution if you have allergies or sensitivities to any of the listed ingredients. Pregnant or nursing mothers and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Use only as directed. If gastrointestinal discomfort (including bloating, cramps, diarrhea, or other digestive upset) or other sensitivity is experienced stop taking the product immediately. If you are pregnant, nursing, or have a medical condition, please consult with your physician before use. If you have any questions about consuming this dietary supplement, consult with your health care professional before using. If you use prescription drugs or over-the-counter medications, are unaware of your current medical condition or have a pre-existing medical condition(s), consult with your health care professional before using. Discontinue use immediately if you experience any adverse symptoms or reactions while taking this product. Discontinue use 2 weeks prior to surgery. Do not use if your health status is unknown. Do not use if safety seal is damaged or missing. Keep out of reach of children and pets. Store in a cool, dry place, away from heat moisture. Use this product as a food supplement only. Do not use for weight reduction.
Additional Details
2 months supply
Vegan and non-GMO Vitamin C capsule solution featuring citrus bioflavonoids, quercetin, rose hips, elderberry extracts, and zinc all-in-one.
See all ingredients
Ingredients:
Vitamin C (as Ascorbic Acid), Zinc (as Zinc Amino Acid Chelate), Citrus Bioflavonoid Complex: Grapefruit Powder (Fruit), Lemon Powder (Peel), Orange Powder (Fruit), Quercetin Dihydrate, Rose Hips Extract (Fruit), Elderberry Extract (Fruit; Std. to 5% Flavanoids). Other Ingredients: Methylcellulose Capsule.
Pairs With
References
Vitamin C Complex
Chambial S, Dwivedi S, Shukla KK, John PJ, Sharma P. Vitamin C in disease prevention and cure: an overview. Indian J Clin Biochem. 2013;28(4):314ā328. doi: 10.1007/s12291-013-0375-3
Traber MG, Stevens JF. Vitamins C and E: beneficial effects from a mechanistic perspective. Free Radic Biol Med. 2011;51(5):1000ā1013. doi: 10.1016/j.freeradbiomed.2011.05.017
See more
Padayatty, S. J., Katz, A., Wang, Y., Eck, P., Kwon, O., Lee, J. H., Chen, S., Corpe, C., Dutta, A., Dutta, S. K., & Levine, M. (2003). Vitamin C as an antioxidant: evaluation of its role in disease prevention. Journal of the American College of Nutrition, 22(1), 18ā35. DOI: 10.1080/07315724.2003.10719272
Pehlivan, Fadime. (2017). Vitamin C: An Antioxidant Agent. 10.5772/intechopen.69660. DOI: 10.5772/intechopen.69660
A. Bendich, L.J. Machlin, O. Scandurra, G.W. Burton, D.D.M. Wayner, The antioxidant role of vitamin C, Advances in Free Radical Biology & Medicine, Volume 2, Issue 2, 1986, 419-444, 8755-9668. https://doi.org/10.1016/S8755-9668(86)80021-7
Marc BĆ¼rzle, Matthias A. Hediger. Chapter Eleven: Functional and Physiological Role of Vitamin C Transporters. Mark O. Bevensee. Current Topics in Membranes. Academic Press. 70. 2012. 357-375. 1063-5823. 9780123943163. https://doi.org/10.1016/B978-0-12-394316-3.00011-9
Akbari, Abolfazl & Jelodar, Gholamali & Nazifi, Saeed & Sajedianfard, Javad. (2016). An Overview of The characteristics and Function of Vitamin C in Various Tissues: Relying on its Antioxidant Function. Zahedan Journal of Research in Medical Sciences. In Press. DOI: 10.17795/zjrms-4037
Chakraborthy, Aratirika & Ramani, Pratibha & Sherlin, Herald & Premkumar, Priya & Natesan, Anuja. (2014). Antioxidant and pro-oxidant activity of Vitamin C in oral environment. Indian journal of dental research : official publication of Indian Society for Dental Research. 25. 499-504. DOI: 10.4103/0970-9290.142547
Sirmali, Rana & GiniÅ, Zeynep & Sirmali, Mehmet & Solak, Okan & Åeliman, BengĆ¼ & AÄaƧkiran, Yetkin & DelibaÅ, Namık. (2014). Vitamin C as an antioxidant: evaluation of its role on pulmonary contusion experimental model. Turkish journal of medical sciences. 44. 905-13. DOI: 10.3906/sag-1309-139
Citrus Bioflavonoids
Stevens, Y., Rymenant, E. V., Grootaert, C., Camp, J. V., Possemiers, S., Masclee, A., & Jonkers, D. (2019). The Intestinal Fate of Citrus Flavanones and Their Effects on Gastrointestinal Health. Nutrients, 11(7), 1464. DOI: 10.3390/nu11071464
Testai L, Calderone V. Nutraceutical Value of Citrus Flavanones and Their Implications in Cardiovascular Disease. Nutrients. 2017;9(5):502. Published 2017 May 16. doi: 10.3390/nu9050502
Barreca, D., Gattuso, G., Bellocco, E., Calderaro, A., Trombetta, D., Smeriglio, A., LaganĆ , G., Daglia, M., Meneghini, S., & Nabavi, S. M. (2017). Flavanones: Citrus phytochemical with health-promoting properties. BioFactors (Oxford, England), 43(4), 495ā506. DOI: 10.1002/biof.1363
Sharma, M., Akhtar, N., Sambhav, K., Shete, G., Bansal, A. K., & Sharma, S. S. (2015). Emerging potential of citrus flavanones as an antioxidant in diabetes and its complications. Current topics in medicinal chemistry, 15(2), 187ā195. DOI: 10.2174/1568026615666141209163013
Chanet, A., Milenkovic, D., Manach, C., Mazur, A., & Morand, C. (2012). Citrus flavanones: what is their role in cardiovascular protection?. Journal of agricultural and food chemistry, 60(36), 8809ā8822. DOI: 10.1021/jf300669s
Zaidun, N. H., Thent, Z. C., & Latiff, A. A. (2018). Combating oxidative stress disorders with citrus flavonoid: Naringenin. Life sciences, 208, 111ā122. DOI: 10.1016/j.lfs.2018.07.017
Assini, J. M., Mulvihill, E. E., & Huff, M. W. (2013). Citrus flavonoids and lipid metabolism. Current opinion in lipidology, 24(1), 34ā40. DOI: 10.1097/MOL.0b013e32835c07fd
Asgary, S., Naderi, G., & Askari, N. (2005). Protective effect of flavonoids against red blood cell hemolysis by free radicals. Experimental and clinical cardiology, 10(2), 88ā90. PMCID: PMC2716227
Elderberry Powder
Sidor, Andrzej & Gramza Michalowska, Anna. (2014). Advanced research on the antioxidant and health benefit of elderberry (Sambucus nigra) in food ā a review. Journal of Functional Foods. 18. DOI: 10.1016/j.jff.2014.07.012
Porter, R. S., & Bode, R. F. (2017). A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products. Phytotherapy research : PTR, 31(4), 533ā554. DOI: 10.1002/ptr.5782
Zakay-Rones, Z., Thom, E., Wollan, T., & Wadstein, J. (2004). Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections. The Journal of international medical research, 32(2), 132ā140. DOI: 10.1177/147323000403200205
Barak, V., Halperin, T., & Kalickman, I. (2001). The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. European cytokine network, 12(2), 290ā296. PMID: 11399518
Hawkins, J., Baker, C., Cherry, L., & Dunne, E. (2019). Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials. Complementary therapies in medicine, 42, 361ā365. DOI: 10.1016/j.ctim.2018.12.004
Tiralongo E, Wee SS, Lea RA. Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial. Nutrients. 2016;8(4):182. Published 2016 Mar 24. doi: 10.3390/nu8040182
Porter, R. S., & Bode, R. F. (2017). A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products. Phytotherapy research : PTR, 31(4), 533ā554. DOI: 10.1002/ptr.5782
Quercetin
Selamoglu, Zeliha. (2016). Antioxidant Activity of Quercetin: A Mechanistic Review. Turkish Journal of Agriculture - Food Science and Technology. 4. 10.24925/turjaf.v4i12.1134-1138.1069. DOI: 10.24925/turjaf.v4i12.1134-1138.1069
Anand David AV, Arulmoli R, Parasuraman S. Overviews of Biological Importance of Quercetin: A Bioactive Flavonoid. Pharmacogn Rev. 2016;10(20):84ā89. doi: 10.4103/0973-7847.194044
Serban, M. C., Sahebkar, A., Zanchetti, A., Mikhailidis, D. P., Howard, G., Antal, D., Andrica, F., Ahmed, A., Aronow, W. S., Muntner, P., Lip, G. Y., Graham, I., Wong, N., Rysz, J., Banach, M., & Lipid and Blood Pressure Metaāanalysis Collaboration (LBPMC) Group (2016). Effects of Quercetin on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Journal of the American Heart Association, 5(7), e002713. DOI: 10.1161/JAHA.115.002713
Xu D, Hu MJ, Wang YQ, Cui YL. Antioxidant Activities of Quercetin and Its Complexes for Medicinal Application. Molecules. 2019;24(6):1123. Published 2019 Mar 21. doi: 10.3390/molecules24061123
AlĆa, M., Mateos, R., Ramos, S., Lecumberri, E., Bravo, L., & Goya, L. (2006). Influence of quercetin and rutin on growth and antioxidant defense system of a human hepatoma cell line (HepG2). European journal of nutrition, 45(1), 19ā28. DOI: 10.1007/s00394-005-0558-7
Robaszkiewicz, A., Balcerczyk, A., & Bartosz, G. (2007). Antioxidative and prooxidative effects of quercetin on A549 cells. Cell biology international, 31(10), 1245ā1250. DOI: 10.1016/j.cellbi.2007.04.009
Kim, G. N., & Jang, H. D. (2009). Protective mechanism of quercetin and rutin using glutathione metabolism on HO-induced oxidative stress in HepG2 cells. Annals of the New York Academy of Sciences, 1171, 530ā537. DOI: 10.1111/j.1749-6632.2009.04690.x
Baghel, Satyendra & Shrivastava, Nikhil & Baghel, PA & Rajput, Sarlesh. (2012). A review of quercetin: Antioxidant and anticancer properties. World J Pharm Pharmaceutical Sci. 1. 146 - 160.
Zinc
Kaltenberg, J., Plum, L. M., Ober-Blƶbaum, J. L., Hƶnscheid, A., Rink, L., & Haase, H. (2010). Zinc signals promote IL-2-dependent proliferation of T cells. European journal of immunology, 40(5), 1496ā1503. DOI: 10.1002/eji.200939574
Shankar, A. H., & Prasad, A. S. (1998). Zinc and immune function: the biological basis of altered resistance to infection. The American journal of clinical nutrition, 68(2 Suppl), 447Sā463S. DOI: 10.1093/ajcn/68.2.447S
Barnett, J. B., Dao, M. C., Hamer, D. H., Kandel, R., Brandeis, G., Wu, D., Dallal, G. E., Jacques, P. F., Schreiber, R., Kong, E., & Meydani, S. N. (2016). Effect of zinc supplementation on serum zinc concentration and T cell proliferation in nursing home elderly: a randomized, double-blind, placebo-controlled trial. The American journal of clinical nutrition, 103(3), 942ā951. DOI: 10.3945/ajcn.115.115188
Barnett JB, Hamer DH, Meydani SN. Low zinc status: a new risk factor for pneumonia in the elderly? Nutrition Reviews. 2010 Jan;68(1):30-37. DOI: 10.1111/j.1753-4887.2009.00253.x
Yasuda, Hiroshi. (2017). The Situation of Zinc Deficiency: Early Assessment and Intervention Are Essential. Biomedical Research on Trace Elements. 125-140. DOI: 10.11299/brte.27.125
HemilƤ H. Zinc lozenges may shorten the duration of colds: a systematic review. Open Respir Med J. 2011;5:51ā58. doi: 10.2174/1874306401105010051
Rerksuppaphol, S., & Rerksuppaphol, L. (2013). A randomized controlled trial of chelated zinc for prevention of the common cold in Thai school children. Paediatrics and international child health, 33(3), 145ā150. DOI: 10.1179/2046905513Y.0000000064
Vitamin C (as Ascorbic Acid), Zinc (as Zinc Amino Acid Chelate), Citrus Bioflavonoid Complex: Grapefruit Powder (Fruit), Lemon Powder (Peel), Orange Powder (Fruit), Quercetin Dihydrate, Rose Hips Extract (Fruit), Elderberry Extract (Fruit; Std. to 5% Flavanoids). Other Ingredients: Methylcellulose Capsule.
Adults take 2 capsules daily with 8 ounces of water or your favorite beverage.Ā May be taken with or without food.
CAUTION: Do not exceed recommended dose. Please use caution if you have allergies or sensitivities to any of the listed ingredients. Pregnant or nursing mothers and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Use only as directed. If gastrointestinal discomfort (including bloating, cramps, diarrhea, or other digestive upset) or other sensitivity is experienced stop taking the product immediately. If you are pregnant, nursing, or have a medical condition, please consult with your physician before use. If you have any questions about consuming this dietary supplement, consult with your health care professional before using. If you use prescription drugs or over-the-counter medications, are unaware of your current medical condition or have a pre-existing medical condition(s), consult with your health care professional before using. Discontinue use immediately if you experience any adverse symptoms or reactions while taking this product. Discontinue use 2 weeks prior to surgery. Do not use if your health status is unknown. Do not use if safety seal is damaged or missing. Keep out of reach of children and pets. Store in a cool, dry place, away from heat moisture. Use this product as a food supplement only. Do not use for weight reduction.
Vitamin C Complex
Chambial S, Dwivedi S, Shukla KK, John PJ, Sharma P. Vitamin C in disease prevention and cure: an overview. Indian J Clin Biochem. 2013;28(4):314ā328. doi: 10.1007/s12291-013-0375-3
Traber MG, Stevens JF. Vitamins C and E: beneficial effects from a mechanistic perspective. Free Radic Biol Med. 2011;51(5):1000ā1013. doi: 10.1016/j.freeradbiomed.2011.05.017
Padayatty, S. J., Katz, A., Wang, Y., Eck, P., Kwon, O., Lee, J. H., Chen, S., Corpe, C., Dutta, A., Dutta, S. K., & Levine, M. (2003). Vitamin C as an antioxidant: evaluation of its role in disease prevention. Journal of the American College of Nutrition, 22(1), 18ā35. DOI: 10.1080/07315724.2003.10719272
Pehlivan, Fadime. (2017). Vitamin C: An Antioxidant Agent. 10.5772/intechopen.69660. DOI: 10.5772/intechopen.69660
A. Bendich, L.J. Machlin, O. Scandurra, G.W. Burton, D.D.M. Wayner, The antioxidant role of vitamin C, Advances in Free Radical Biology & Medicine, Volume 2, Issue 2, 1986, 419-444, 8755-9668. https://doi.org/10.1016/S8755-9668(86)80021-7
Marc BĆ¼rzle, Matthias A. Hediger. Chapter Eleven: Functional and Physiological Role of Vitamin C Transporters. Mark O. Bevensee. Current Topics in Membranes. Academic Press. 70. 2012. 357-375. 1063-5823. 9780123943163. https://doi.org/10.1016/B978-0-12-394316-3.00011-9
Akbari, Abolfazl & Jelodar, Gholamali & Nazifi, Saeed & Sajedianfard, Javad. (2016). An Overview of The characteristics and Function of Vitamin C in Various Tissues: Relying on its Antioxidant Function. Zahedan Journal of Research in Medical Sciences. In Press. DOI: 10.17795/zjrms-4037
Chakraborthy, Aratirika & Ramani, Pratibha & Sherlin, Herald & Premkumar, Priya & Natesan, Anuja. (2014). Antioxidant and pro-oxidant activity of Vitamin C in oral environment. Indian journal of dental research : official publication of Indian Society for Dental Research. 25. 499-504. DOI: 10.4103/0970-9290.142547
Sirmali, Rana & GiniÅ, Zeynep & Sirmali, Mehmet & Solak, Okan & Åeliman, BengĆ¼ & AÄaƧkiran, Yetkin & DelibaÅ, Namık. (2014). Vitamin C as an antioxidant: evaluation of its role on pulmonary contusion experimental model. Turkish journal of medical sciences. 44. 905-13. DOI: 10.3906/sag-1309-139
Citrus Bioflavonoids
Stevens, Y., Rymenant, E. V., Grootaert, C., Camp, J. V., Possemiers, S., Masclee, A., & Jonkers, D. (2019). The Intestinal Fate of Citrus Flavanones and Their Effects on Gastrointestinal Health. Nutrients, 11(7), 1464. DOI: 10.3390/nu11071464
Testai L, Calderone V. Nutraceutical Value of Citrus Flavanones and Their Implications in Cardiovascular Disease. Nutrients. 2017;9(5):502. Published 2017 May 16. doi: 10.3390/nu9050502
Barreca, D., Gattuso, G., Bellocco, E., Calderaro, A., Trombetta, D., Smeriglio, A., LaganĆ , G., Daglia, M., Meneghini, S., & Nabavi, S. M. (2017). Flavanones: Citrus phytochemical with health-promoting properties. BioFactors (Oxford, England), 43(4), 495ā506. DOI: 10.1002/biof.1363
Sharma, M., Akhtar, N., Sambhav, K., Shete, G., Bansal, A. K., & Sharma, S. S. (2015). Emerging potential of citrus flavanones as an antioxidant in diabetes and its complications. Current topics in medicinal chemistry, 15(2), 187ā195. DOI: 10.2174/1568026615666141209163013
Chanet, A., Milenkovic, D., Manach, C., Mazur, A., & Morand, C. (2012). Citrus flavanones: what is their role in cardiovascular protection?. Journal of agricultural and food chemistry, 60(36), 8809ā8822. DOI: 10.1021/jf300669s
Zaidun, N. H., Thent, Z. C., & Latiff, A. A. (2018). Combating oxidative stress disorders with citrus flavonoid: Naringenin. Life sciences, 208, 111ā122. DOI: 10.1016/j.lfs.2018.07.017
Assini, J. M., Mulvihill, E. E., & Huff, M. W. (2013). Citrus flavonoids and lipid metabolism. Current opinion in lipidology, 24(1), 34ā40. DOI: 10.1097/MOL.0b013e32835c07fd
Asgary, S., Naderi, G., & Askari, N. (2005). Protective effect of flavonoids against red blood cell hemolysis by free radicals. Experimental and clinical cardiology, 10(2), 88ā90. PMCID: PMC2716227
Elderberry Powder
Sidor, Andrzej & Gramza Michalowska, Anna. (2014). Advanced research on the antioxidant and health benefit of elderberry (Sambucus nigra) in food ā a review. Journal of Functional Foods. 18. DOI: 10.1016/j.jff.2014.07.012
Porter, R. S., & Bode, R. F. (2017). A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products. Phytotherapy research : PTR, 31(4), 533ā554. DOI: 10.1002/ptr.5782
Zakay-Rones, Z., Thom, E., Wollan, T., & Wadstein, J. (2004). Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections. The Journal of international medical research, 32(2), 132ā140. DOI: 10.1177/147323000403200205
Barak, V., Halperin, T., & Kalickman, I. (2001). The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. European cytokine network, 12(2), 290ā296. PMID: 11399518
Hawkins, J., Baker, C., Cherry, L., & Dunne, E. (2019). Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials. Complementary therapies in medicine, 42, 361ā365. DOI: 10.1016/j.ctim.2018.12.004
Tiralongo E, Wee SS, Lea RA. Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial. Nutrients. 2016;8(4):182. Published 2016 Mar 24. doi: 10.3390/nu8040182
Porter, R. S., & Bode, R. F. (2017). A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products. Phytotherapy research : PTR, 31(4), 533ā554. DOI: 10.1002/ptr.5782
Quercetin
Selamoglu, Zeliha. (2016). Antioxidant Activity of Quercetin: A Mechanistic Review. Turkish Journal of Agriculture - Food Science and Technology. 4. 10.24925/turjaf.v4i12.1134-1138.1069. DOI: 10.24925/turjaf.v4i12.1134-1138.1069
Anand David AV, Arulmoli R, Parasuraman S. Overviews of Biological Importance of Quercetin: A Bioactive Flavonoid. Pharmacogn Rev. 2016;10(20):84ā89. doi: 10.4103/0973-7847.194044
Serban, M. C., Sahebkar, A., Zanchetti, A., Mikhailidis, D. P., Howard, G., Antal, D., Andrica, F., Ahmed, A., Aronow, W. S., Muntner, P., Lip, G. Y., Graham, I., Wong, N., Rysz, J., Banach, M., & Lipid and Blood Pressure Metaāanalysis Collaboration (LBPMC) Group (2016). Effects of Quercetin on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Journal of the American Heart Association, 5(7), e002713. DOI: 10.1161/JAHA.115.002713
Xu D, Hu MJ, Wang YQ, Cui YL. Antioxidant Activities of Quercetin and Its Complexes for Medicinal Application. Molecules. 2019;24(6):1123. Published 2019 Mar 21. doi: 10.3390/molecules24061123
AlĆa, M., Mateos, R., Ramos, S., Lecumberri, E., Bravo, L., & Goya, L. (2006). Influence of quercetin and rutin on growth and antioxidant defense system of a human hepatoma cell line (HepG2). European journal of nutrition, 45(1), 19ā28. DOI: 10.1007/s00394-005-0558-7
Robaszkiewicz, A., Balcerczyk, A., & Bartosz, G. (2007). Antioxidative and prooxidative effects of quercetin on A549 cells. Cell biology international, 31(10), 1245ā1250. DOI: 10.1016/j.cellbi.2007.04.009
Kim, G. N., & Jang, H. D. (2009). Protective mechanism of quercetin and rutin using glutathione metabolism on HO-induced oxidative stress in HepG2 cells. Annals of the New York Academy of Sciences, 1171, 530ā537. DOI: 10.1111/j.1749-6632.2009.04690.x
Baghel, Satyendra & Shrivastava, Nikhil & Baghel, PA & Rajput, Sarlesh. (2012). A review of quercetin: Antioxidant and anticancer properties. World J Pharm Pharmaceutical Sci. 1. 146 - 160.
Zinc
Kaltenberg, J., Plum, L. M., Ober-Blƶbaum, J. L., Hƶnscheid, A., Rink, L., & Haase, H. (2010). Zinc signals promote IL-2-dependent proliferation of T cells. European journal of immunology, 40(5), 1496ā1503. DOI: 10.1002/eji.200939574
Shankar, A. H., & Prasad, A. S. (1998). Zinc and immune function: the biological basis of altered resistance to infection. The American journal of clinical nutrition, 68(2 Suppl), 447Sā463S. DOI: 10.1093/ajcn/68.2.447S
Barnett, J. B., Dao, M. C., Hamer, D. H., Kandel, R., Brandeis, G., Wu, D., Dallal, G. E., Jacques, P. F., Schreiber, R., Kong, E., & Meydani, S. N. (2016). Effect of zinc supplementation on serum zinc concentration and T cell proliferation in nursing home elderly: a randomized, double-blind, placebo-controlled trial. The American journal of clinical nutrition, 103(3), 942ā951. DOI: 10.3945/ajcn.115.115188
Barnett JB, Hamer DH, Meydani SN. Low zinc status: a new risk factor for pneumonia in the elderly? Nutrition Reviews. 2010 Jan;68(1):30-37. DOI: 10.1111/j.1753-4887.2009.00253.x
Yasuda, Hiroshi. (2017). The Situation of Zinc Deficiency: Early Assessment and Intervention Are Essential. Biomedical Research on Trace Elements. 125-140. DOI: 10.11299/brte.27.125
HemilƤ H. Zinc lozenges may shorten the duration of colds: a systematic review. Open Respir Med J. 2011;5:51ā58. doi: 10.2174/1874306401105010051
Rerksuppaphol, S., & Rerksuppaphol, L. (2013). A randomized controlled trial of chelated zinc for prevention of the common cold in Thai school children. Paediatrics and international child health, 33(3), 145ā150. DOI: 10.1179/2046905513Y.0000000064
Customer Reviews
5.0 Based on 29 Reviews
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- Vitamin C
- Zinc
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E
01/26/2023
ESHA
United StatesComplete booster
It has everything! Vitamin C complex 1285mg, Elderberry, Quercetin and 15mg zinc. Just grab in the morning, will fresh for whole days. In my daily, I'm only consume 1 pills since I'm only need about 1000mg a day.
T
01/25/2023
tina
United StatesEasy to take
These are super easy to take with no after taste or stomach upset. I need the extra for my immunity system especially during winter months. These are non GMO, vegan and made in the USA. They have extra vitamins/minerals added for an extra boost.
M
01/24/2023
Miranda
United StatesAirborne substitute
I use this instead of airborne sometimes if Iām feeling under the weather
B
01/23/2023
Bonnie
United StatesImmunity boost!
This time of year, I like to add a little extra vitamin C to my day to help ward off some of the sicknesses going around. This one is great! So far, I really like it. It's easy to take, doesn't have any strange aftertaste, and seems to do the trick. I love when I can take a quick vitamin and not have to think about it the rest of the day.
DP
01/19/2023
Dawn P.
United StatesAwesome stuff!
After taking these I feel more productive during the day. Two tablets a day and that's all you need! Highly recommend.
